Probiotics in inflammatory bowel disease: New insight to pathogenesis or a possible therapeutic alternative?

1999 ◽  
Vol 116 (5) ◽  
pp. 1246-1249 ◽  
Author(s):  
Massimo Campieri ◽  
Paolo Gionchetti
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Therapeutic Alternative ◽  
Inflammatory Bowel

scholarly journals Sphingosine-1-Phosphate Lyase Inhibition Alters the S1P Gradient and Ameliorates Crohn’s-Like Ileitis by Suppressing Thymocyte Maturation

2019 ◽  
Vol 26 (2) ◽  
pp. 216-228 ◽  
Author(s):  
Thangaraj Karuppuchamy ◽  
Christopher J Tyler ◽  
Luke R Lundborg ◽  
Tamara Pérez-Jeldres ◽  
Abigail K Kimball ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Effective Alternative ◽  
Receptor Agonists ◽  
Therapeutic Alternative ◽  
Sphingosine 1 Phosphate ◽  
Inflammatory Bowel ◽  
S1p Receptor ◽  
S1p Lyase

Sphingosine-1-phosphate (S1P) receptor agonists are a promising therapeutic alternative to anti-integrin antibodies in inflammatory bowel disease. Here, we report that modulation of tissue S1P levels via inhibition of the S1P lyase might be an effective alternative, acting by interference with thymocyte maturation.

Detection of possible inflammatory bowel disease-related genes using microarray analysis

2001 ◽  
Vol 120 (5) ◽  
pp. A455-A455
Author(s):  
E MANNICK ◽  
M SERRANO ◽  
J BONOMOLO ◽  
M LAU ◽  
J UDALLJR ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Microarray Analysis ◽  
Bowel Disease ◽  
Inflammatory Bowel ◽  
Disease Related Genes
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