scholarly journals The presence of cholecystokinin B receptors in rat pituitary gland and GH3, a rat anterior pituitary tumor cell line.

1991 ◽  
Vol 55 ◽  
pp. 355
Author(s):  
Mari Takamiya ◽  
Hiroyuki Yoshizaki ◽  
Atsuko Hanayama ◽  
Hiromi Nagase ◽  
Tsutomu Kudoh ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Pituitary Gland ◽  
Cell Line ◽  
Pituitary Tumor ◽  
Anterior Pituitary ◽  
Tumor Cell Line ◽  
Rat Pituitary ◽  
Pituitary Tumor Cell

Bihormonal Cells Producing Gonadotropins and Prolactin in a Rat Pituitary Tumor Cell Line (RC-4B/C)

1991 ◽  
Vol 54 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Jolanta Polkowska ◽  
Annette Bérault ◽  
Ilse Hurbain-Kosmath ◽  
Gilles Jolly ◽  
Marian Jutisz
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Pituitary Tumor ◽  
Tumor Cell Line ◽  
Rat Pituitary ◽  
Pituitary Tumor Cell

scholarly journals Sorting and secretion of adrenocorticotropin in a pituitary tumor cell line after perturbation of the level of a secretory granule-specific proteoglycan.

1984 ◽  
Vol 99 (6) ◽  
pp. 2223-2230 ◽  
Author(s):  
T L Burgess ◽  
R B Kelly
Keyword(s):  
Tumor Cell ◽  
Thin Layer ◽  
Chondroitin Sulfate ◽  
Cell Line ◽  
Secretory Granule ◽  
Pituitary Tumor ◽  
Anterior Pituitary ◽  
Tumor Cell Line ◽  
Pituitary Tumor Cell

A mouse anterior pituitary tumor cell line (AtT-20) that secretes adrenocorticotropin and beta endorphin sorts the proteins it transports to the surface into two exocytotic pathways. AtT-20 cells also synthesize a secretory granule-specific sulfated molecule and secrete it on stimulation (Moore, H.-P., B. Gumbiner, and R. B. Kelly, 1983, J. Cell Biol., 97:810-817). We show here that this molecule is sensitive to proteolysis and that the residual sulfated material co-migrates with a chondroitin sulfate standard on thin-layer electrophoresis. Furthermore, this sulfated molecule is completely sensitive to chondroitinase ABC digestion. Thus the secretory granule-specific sulfated molecule is a proteoglycan with chondroitin sulfate side chains. We examined the role of proteoglycans in the sorting and secretion of adrenocorticotropin in AtT-20 cells by severely decreasing the amount of this vesicle-specific proteoglycan in two ways. First, a xyloside was used to inhibit proteoglycan biosynthesis; second, a variant of the AtT-20 cell line was isolated that synthesized little of the sulfated proteoglycan. In neither case was the sorting or secretion of adrenocorticotropin detectably altered, suggesting that the proteoglycan is not required for these processes.

scholarly journals Effect of cholecystokinin-8 on the intracellular Ca2+ concentration in GH3, a rat anterior pituitary tumor cell line.

1991 ◽  
Vol 55 ◽  
pp. 115
Author(s):  
Hiromi Nagase ◽  
Toshikazu Kuwahara ◽  
Tsutomu Kudoh ◽  
Hiroyuki Yoshizaki ◽  
Mari Takamiya ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Pituitary Tumor ◽  
Anterior Pituitary ◽  
Tumor Cell Line ◽  
Pituitary Tumor Cell

Gonadotropes in a novel rat pituitary tumor cell line, RC-4B/C. Establishment and partial characterization of the cell line

1990 ◽  
Vol 26 (5) ◽  
pp. 431-440 ◽  
Author(s):  
Ilse Hurbain-Kosmath ◽  
Annette Berault ◽  
Nadine Noel ◽  
Jolanta Polkowska ◽  
Anne Bohin ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Pituitary Tumor ◽  
Tumor Cell Line ◽  
Partial Characterization ◽  
Rat Pituitary ◽  
Pituitary Tumor Cell

Effects of TGFβ1 on gene expression in the HP75 human pituitary tumor cell line identified by gene expression profiling

Endocrine ◽  
2008 ◽  
Vol 33 (1) ◽  
pp. 62-76 ◽  
Author(s):  
Katharina H. Ruebel ◽  
Alexey A. Leontovich ◽  
Yoshinori Tanizaki ◽  
Long Jin ◽  
Gail A. Stilling ◽  
...  
Keyword(s):  
Gene Expression ◽  
Tumor Cell ◽  
Gene Expression Profiling ◽  
Cell Line ◽  
Expression Profiling ◽  
Pituitary Tumor ◽  
Tumor Cell Line ◽  
Human Pituitary ◽  
Human Pituitary Tumor ◽  
Pituitary Tumor Cell
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