scholarly journals Substantial increase of the inhibitory activity of Mirabilis antiviral protein by an elimination of the disulfide bond with genetic engineering.

1991 ◽  
Vol 266 (35) ◽  
pp. 23558-23560
Author(s):  
N. Habuka ◽  
M. Miyano ◽  
J. Kataoka ◽  
H. Tsuge ◽  
H. Ago ◽  
...  
1985 ◽  
Vol 33 (1) ◽  
pp. 74-83 ◽  
Author(s):  
EISHIN KATO ◽  
KOJI YAMAMOTO ◽  
TOSHIO BABA ◽  
TOSHIO WATANABE ◽  
YOICHI KAWASHIMA ◽  
...  

Biochemistry ◽  
1991 ◽  
Vol 30 (21) ◽  
pp. 5225-5229 ◽  
Author(s):  
Juan J. Calvete ◽  
Wolfram Schaefer ◽  
Tomasz Soszka ◽  
Weiqu Lu ◽  
Jacquelynn Cook ◽  
...  

Plant Disease ◽  
1999 ◽  
Vol 83 (12) ◽  
pp. 1116-1121 ◽  
Author(s):  
Jorge M. Vivanco ◽  
Maddalena Querci ◽  
Luis F. Salazar

Extracts of Mirabilis jalapa (Nyctaginaceae), containing a ribosome inactivating protein (RIP) called Mirabilis antiviral protein (MAP), were tested against infection by potato virus X, potato virus Y, potato leaf roll virus, and potato spindle tuber viroid. Root extracts of M. jalapa sprayed on test plants 24 h before virus or viroid inoculation inhibited infection by almost 100%, as corroborated by infectivity assays and the nucleic acid spot hybridization test. Antiviral activity of MAP extracts was observed against mechanically transmitted viruses but not against aphid-transmitted viruses. Purified MAP showed the same antiviral effect as the crude extracts.


1992 ◽  
Vol 267 (11) ◽  
pp. 7758-7760
Author(s):  
N Habuka ◽  
M Miyano ◽  
J Kataoka ◽  
H Tsuge ◽  
M Noma

1992 ◽  
Vol 226 (1) ◽  
pp. 281-283 ◽  
Author(s):  
Masashi Miyano ◽  
Krzystof Appelt ◽  
Masatoshi Arita ◽  
Noriyuki Habuka ◽  
Jiro Kataoka ◽  
...  

1985 ◽  
Vol 16 (26) ◽  
Author(s):  
E. KATO ◽  
K. YAMAMOTO ◽  
T. BABA ◽  
T. WATANABE ◽  
Y. KAWASHIMA ◽  
...  

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