Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor. Role of conserved cysteines in receptor function.

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Receptor Function ◽

The Efficacy of LY293558 in Blocking Seizures and Associated Morphological, and Behavioral Alterations Induced by Soman in Immature Male Rats and the Role of the M1 Muscarinic Acetylcholine Receptor in Organophosphate Induced Seizures

10.21236/ad1012848 ◽

2015 ◽

Author(s):

Steven L. Miller

Keyword(s):

Acetylcholine Receptor ◽

Male Rats ◽

Behavioral Alterations ◽

Immature Male ◽

TYR381 in transmembrane domain six of the rat M1-muscarinic acetylcholine receptor plays a dual role in receptor function

Life Sciences ◽

10.1016/s0024-3205(99)90483-6 ◽

1999 ◽

Vol 64 (6-7) ◽

pp. 564 ◽

Cited By ~ 2

Author(s):

Stuart D.C. Ward ◽

Edward C. Hulme

Keyword(s):

Acetylcholine Receptor ◽

Transmembrane Domain ◽

Dual Role ◽

Receptor Function ◽

Alanine-Scanning Mutagenesis of Transmembrane Domain 6 of the M1 Muscarinic Acetylcholine Receptor Suggests that Tyr381 Plays Key Roles in Receptor Function

Molecular Pharmacology ◽

10.1124/mol.56.5.1031 ◽

1999 ◽

Vol 56 (5) ◽

pp. 1031-1041 ◽

Cited By ~ 49

Author(s):

Stuart D. C. Ward ◽

Carol A. M. Curtis ◽

Edward C. Hulme

Keyword(s):

Acetylcholine Receptor ◽

Transmembrane Domain ◽

Receptor Function ◽

Alanine Scanning Mutagenesis ◽

Alanine Scanning ◽

Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor. Analysis of the role of N-glycosylation in receptor expression and function.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)45299-9 ◽

1990 ◽

Vol 265 (34) ◽

pp. 20887-20892 ◽

Cited By ~ 3

Author(s):

C J van Koppen ◽

N M Nathanson

Keyword(s):

Acetylcholine Receptor ◽

Receptor Expression ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

And Function

5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated Galpha(q) signalling in patients with psychiatric disorders

10.26226/morressier.5b68175eb56e9b005965c3a3 ◽

2018 ◽

Author(s):

Yuji Odagaki

Keyword(s):

Psychiatric Disorders ◽

Acetylcholine Receptor ◽

5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated activation of Gαq/11 in postmortem dorsolateral prefrontal cortex of opiate addicts

Pharmacological Reports ◽

10.1007/s43440-021-00248-w ◽

2021 ◽

Author(s):

Yuji Odagaki ◽

Masakazu Kinoshita ◽

J. Javier Meana ◽

Luis F. Callado ◽

Jesús A. García-Sevilla

Keyword(s):

Prefrontal Cortex ◽

Acetylcholine Receptor ◽

Dorsolateral Prefrontal Cortex ◽

Dorsolateral Prefrontal ◽

Opiate Addicts ◽

Pharmacological Assessment of M1 Muscarinic Acetylcholine Receptor-Gq/11 Protein Coupling in Membranes Prepared from Postmortem Human Brain Tissue

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.108.137968 ◽

2008 ◽

Vol 325 (3) ◽

pp. 869-874 ◽

Cited By ~ 20

Author(s):

Hasib Salah-Uddin ◽

David R. Thomas ◽

Ceri H. Davies ◽

Jim J. Hagan ◽

Martyn D. Wood ◽

...

Keyword(s):

Human Brain ◽

Brain Tissue ◽

Acetylcholine Receptor ◽

Human Brain Tissue ◽

Postmortem Human Brain ◽

Protein Coupling ◽

Direct SUMOylation of M1 muscarinic acetylcholine receptor increases its ligand‐binding affinity and signal transduction

The FASEB Journal ◽

10.1096/fj.201800936r ◽

2018 ◽

Vol 33 (3) ◽

pp. 3237-3251 ◽

Cited By ~ 3

Author(s):

Jianrong Xu ◽

Panpan Tan ◽

Hui Li ◽

Yongyao Cui ◽

Yu Qiu ◽

...

Keyword(s):

Signal Transduction ◽

Ligand Binding ◽

Binding Affinity ◽

Acetylcholine Receptor ◽

The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity

The EMBO Journal ◽

10.1093/emboj/16.15.4597 ◽

1997 ◽

Vol 16 (15) ◽

pp. 4597-4605 ◽

Cited By ~ 144

Author(s):

W. Tsai

Keyword(s):

Ion Channel ◽

Acetylcholine Receptor ◽

Egf Receptor ◽

Channel Activity ◽

P2-317: Suvn-i1312004, a novel M1 muscarinic acetylcholine receptor-positive allosteric modulator: Potential for the treatment of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2015.06.859 ◽

2015 ◽

Vol 11 (7S_Part_13) ◽

pp. P615-P616

Author(s):

Renny Abraham ◽

Ramkumar Subramanian ◽

Rajesh Babu Medapati ◽

Ravirala Venkateshwarlu ◽

Sumanth Yathavakilla ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽