Determination of plasma and urinary levels of an analgesic anti-inflammatory α[4-(2-isoindolinyl)phenyl]propionic acid derivative by gas—liquid chromatography

1974 ◽  
Vol 92 (1) ◽  
pp. 61-68 ◽  
Author(s):  
G.P. Tosolini ◽  
A. Forgione ◽  
E. Moro ◽  
V. Mandelli
Keyword(s):  
Liquid Chromatography ◽  
Propionic Acid ◽  
Acid Derivative ◽  
Gas Liquid Chromatography ◽  
Phenyl Propionic Acid ◽  
Urinary Levels ◽  
Anti Inflammatory ◽  
Propionic Acid Derivative

Brufen in rheumatoid arthritis

1969 ◽  
Vol 7 (9) ◽  
pp. 35-36
Keyword(s):  
Rheumatoid Arthritis ◽  
Acetic Acid ◽  
Propionic Acid ◽  
Acid Derivative ◽  
Phenylalkanoic Acid ◽  
Anti Inflammatory ◽  
Propionic Acid Derivative

Ibuprofen (Brufen - Boots) is a propionic acid derivative of the group of anti-inflammatory compounds of the phenylalkanoic acid series.1 Ibufenac (Dytransin - Boots) which we reviewed in 19662 is an acetic acid member of the same series. Boots withdrew ibufenac in 1968 because it was suspected of causing jaundice.3

Simplified Method for the Determination of Propionates in Bread: Isolation by Micro diffusion

1972 ◽  
Vol 55 (1) ◽  
pp. 04-06
Author(s):  
A B Karasz ◽  
W Hallenbeck
Keyword(s):  
Liquid Chromatography ◽  
Elevated Temperature ◽  
Propionic Acid ◽  
Column Chromatography ◽  
Steam Distillation ◽  
Isolation Procedure ◽  
Gas Liquid Chromatography ◽  
Simultaneous Processing ◽  
Simplified Method

Abstract In the method presented, propionic acid is isolated from bread by microdiffusion at an elevated temperature in preparation for determination by gas-liquid chromatography. This isolation procedure is simple, utilizes inexpensive equipment, and permits the simultaneous processing of a large number of samplef. Results obtained by microdiffusion agree closely with those obtained by steam distillation according to AOAC 14.089. After isolation by either microdiffusion or steam distillation, propionic acid in all samples was determined by gas-liquid chromatography as described in 18.038 rather than partition column chromatography as described in 14.090-14.091. An average of 98% of the propionic acid found by using steam distillation was found by using the microdiffusion technique.

scholarly journals Enhanced Dissolution Rate of Tiaprofenic Acid Using Gelucire®44/14*

2002 ◽  
Vol 70 (3) ◽  
pp. 295-307 ◽  
Author(s):  
Saygh M. S. ◽  
Uzunkaya G. ◽  
Özsoy Y. ◽  
Araman A.
Keyword(s):  
Dissolution Rate ◽  
Propionic Acid ◽  
Acid Derivative ◽  
Tiaprofenic Acid ◽  
Inflammatory Drug ◽  
Enhanced Dissolution ◽  
Anti Inflammatory ◽  
Propionic Acid Derivative

Tiaprofenic acid (TA), racemic (5-benzoyl-2-thieny1)-propionic acid (Fig. 1) is a 2-aryl propionic acid derivative nonsteroidal anti-inflammatory drug (1) [...]

GASCHROMATOGRAPHIC DETERMINATION OF STEROIDS IN THE URINE OF PATIENTS WITH CUSHING'S SYNDROME

1971 ◽  
Vol 67 (2) ◽  
pp. 303-315 ◽  
Author(s):  
A. J. Moolenaar ◽  
A. P. van Seters
Keyword(s):  
Liquid Chromatography ◽  
Cushing’S Syndrome ◽  
Normal Subjects ◽  
Diagnostic Value ◽  
Cushing's Syndrome ◽  
Gas Liquid Chromatography ◽  
Obese Subjects

ABSTRACT The 17-oxosteroids were estimated in the urine of 27 patients with Cushing's syndrome by gas-liquid chromatography (G. L. C.). The values of the various steroid fractions are compared with those of normal subjects, patients with thyrotoxicosis and obese subjects. The effect of the age of the patients on the diagnostic value of the invidual 17-oxosteroids and their ratios is discussed.

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