scholarly journals Polymorphic forms of human apolipoprotein[a]: inheritance and relationship of their molecular weights to plasma levels of lipoprotein[a].

1990 ◽  
Vol 31 (4) ◽  
pp. 603-613
Author(s):  
JW Gaubatz ◽  
KI Ghanem ◽  
J Guevara ◽  
ML Nava ◽  
W Patsch ◽  
...  
1994 ◽  
Vol 71 (04) ◽  
pp. 424-427 ◽  
Author(s):  
Masahide Yamazaki ◽  
Hidesaku Asakura ◽  
Hiroshi Jokaji ◽  
Masanori Saito ◽  
Chika Uotani ◽  
...  

SummaryThe mechanisms underlying clinical abnormalities associated with the antiphospholipid antibody syndrome (APAS) have not been elucidated. We measured plasma levels of lipoprotein(a) [Lp(a)], the active form of plasminogen activator inhibitor (active PAI), thrombin-antithrombin III complex (TAT) and soluble thrombomodulin (TM), to investigate the relationship of these factors to thrombotic events in APAS. Mean plasma levels of Lp(a), TAT, active PAI and TM were all significantly higher in patients with aPL than in a control group of subjects. Plasma levels of Lp(a) and active PAI were significantly higher in patients with aPL and arterial thromboses than in patients with aPL but only venous thromboses. There was a significant correlation between plasma levels of Lp(a) and active PAI in patients with aPL. These findings suggest that patients with aPL are in hypercoagulable state. High levels of Lp(a) in plasma may impair the fibrinolytic system resulting in thromboses, especially in the arterial system.


2018 ◽  
Vol 12 (5) ◽  
pp. 1313-1323 ◽  
Author(s):  
Sotirios Tsimikas ◽  
Sergio Fazio ◽  
Nicholas J. Viney ◽  
Shuting Xia ◽  
Joseph L. Witztum ◽  
...  

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
E A Klesareva ◽  
O I Afanasieva ◽  
O A Razova ◽  
E A Utkina ◽  
M I Afanasieva ◽  
...  

2006 ◽  
Vol 902 (1) ◽  
pp. 347-351 ◽  
Author(s):  
JIANGLIN FAN ◽  
MIREILLE CHALLAH ◽  
HIROAKI SHIMOYAMADA ◽  
TERUO WATANABE

1999 ◽  
Vol 255 (3) ◽  
pp. 639-644 ◽  
Author(s):  
Jianglin Fan ◽  
Masahiro Araki ◽  
Lihua Wu ◽  
Mireille Challah ◽  
Hiroaki Shimoyamada ◽  
...  

2005 ◽  
Vol 6 (1) ◽  
pp. 59
Author(s):  
B. Todorova ◽  
K. Tosheska ◽  
D. Labudovic ◽  
S. Alabakovska ◽  
H. Todorov

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