Functional scoliosis as a long-term complication of surgical ligation for patent ductus arteriosus in premature infants

1986 ◽  
Vol 21 (10) ◽  
pp. 855-857 ◽  
Author(s):  
Jean E. Shelton ◽  
Rosemary Julian ◽  
Eric Walburgh ◽  
Elaine Schneider
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Ductus Arteriosus ◽  
Surgical Ligation ◽  
Patent Ductus

Renal Calcifications: A Complication of Long-Term Furosemide Therapy in Preterm Infants

PEDIATRICS ◽  
1982 ◽  
Vol 70 (3) ◽  
pp. 360-363 ◽  
Author(s):  
Karen G. Hufnagle ◽  
Shadid N. Khan ◽  
Duna Penn ◽  
Alexander Cacciarelli ◽  
Paul Williams
Keyword(s):  
Calcium Phosphate ◽  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Chronic Lung Disease ◽  
Stone Formation ◽  
Ductus Arteriosus ◽  
Probable Mechanism ◽  
Calcium Excretion ◽  
Patent Ductus

During the last four years ten premature infants developed renal calcifications while receiving long-term furosemide therapy. The drug was used in infants with patent ductus arteriosus and later in the same infants with chronic lung disease. They had received furosemide in a dose of at least 2 mg/kg/day for at least 12 days before calcifications were noted on abdominal roentgenograms. Calcifications included small flecks, isolated stones, staghorn calculi, and nephrocalcinosis. Analysis of stones received from four infants showed calcium oxalate and calcium phosphate. Infants who were not receiving furosemide had no calcifications. The infants with renal calcifications had rates of calcium excretion ten to 20 times that of normal, age-matched premature infants in our nursery. When chlorothiazide was given to the infants, in addition to furosemide, a four- to 15-fold decrease in calcium excretion and a radiologic dissolution of the renal calcifications were documented. It is concluded that furosemide, in doses of at least 2 mg/kg/day for at least 12 days can be associated with renal calcifications. The probable mechanism of the stone formation is hypercalciuria, primarily caused by furosemide.

Patent Ductus Arteriosus and Short- and Long-Term Respiratory Outcomes

2016 ◽  
Vol 33 (11) ◽  
pp. 1055-1057 ◽  
Author(s):  
Eduardo Bancalari
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Pulmonary Blood Flow ◽  
Ductus Arteriosus ◽  
Lung Damage ◽  
Early Closure ◽  
Short And Long Term ◽  
Respiratory Outcomes ◽  
Patent Ductus

The patency of the ductus arteriosus is very common in extremely premature infants. The increased pulmonary blood flow that results from left-to-right ductal shunting can produce an acute deterioration in lung function and some data suggest that it may increase the risk of chronic lung damage. However, there is no clear evidence that prophylactic or early closure of the patent ductus arteriosus (PDA) results in a clear reduction in bronchopulmonary dysplasia. For this reason, and because of the side effects of the available therapies to close the ductus, there is a wide variation in the approach to the PDA in this population and most clinicians will intervene to close the ductus only in cases of significant shunt with hemodynamic decompensation.

scholarly journals Long-term Results of Ligation of Patent Ductus Arteriosus in Premature Infants.

1992 ◽  
Vol 21 (1) ◽  
pp. 35-40
Author(s):  
Tohru SAKURADA ◽  
Ryosei KURIBAYASHI ◽  
Satoshi SEKINE ◽  
Hiroaki AIDA ◽  
Keiji SEKI ◽  
...  
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Ductus Arteriosus ◽  
Long Term Results ◽  
Patent Ductus

scholarly journals Management of Patent Ductus Arteriosus in Premature Infants in 2020

2021 ◽  
Vol 8 ◽  
Author(s):  
Sarah Parkerson ◽  
Ranjit Philip ◽  
Ajay Talati ◽  
Shyam Sathanandam
Keyword(s):  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Paradigm Shift ◽  
Ductus Arteriosus ◽  
Cardiac Condition ◽  
Practice Variations ◽  
Patent Ductus

The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in neonates. While there have been several studies and thousands of publications on the topic, the decision to treat the PDA is still strongly debated among cardiologists, surgeons, and neonatologists. This is in part due to the shortage of long-term benefits with the interventions studied. Practice variations still exist within sub-specialties and centers. This article briefly summarizes the history, embryology and histology of the PDA. It also succinctly discusses the hemodynamic significance of a PDA which builds the framework to review all the available literature on PDA closure in premature infants, though not a paradigm shift just yet; it introduces transcatheter PDA closure (TCPC) as a possible armament to the clinician for this age-old problem.

Recurrence of Patency of the Ductus Arteriosus After Surgical Ligation in Premature Infants

PEDIATRICS ◽  
1984 ◽  
Vol 73 (1) ◽  
pp. 56-58
Author(s):  
Stephen R. Daniels ◽  
Mark D. Reller ◽  
Samuel Kaplan
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Patent Ductus Arteriosus ◽  
Premature Infants ◽  
Ductus Arteriosus ◽  
Clinical Signs ◽  
Surgical Ligation ◽  
Echocardiographic Evidence ◽  
Patent Ductus

Two premature infants who had surgical ligation of their patent ductus arteriosus are described. These infants initially did well postoperatively but then developed congestive heart failure. Both infants had echocardiographic evidence of recurrence of their patent ductus arteriosus. One of the infants required a repeat ligation procedure. It is important to continue to monitor premature infants for the return of clinical signs of a patent ductus arteriosus after surgical ligation.

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