Angiotensin II increases neurogenic nitric oxide metabolism in mesenteric arteries from hypertensive rats

Life Sciences ◽  
2001 ◽  
Vol 68 (10) ◽  
pp. 1169-1179 ◽  
Author(s):  
Mercedes Ferrer ◽  
M Jesús Alonso ◽  
Mercedes Salaices ◽  
Jesús Marı́n ◽  
Gloria Balfagón
Keyword(s):  
Nitric Oxide ◽  
Angiotensin Ii ◽  
Mesenteric Arteries ◽  
Hypertensive Rats ◽  
Nitric Oxide Metabolism

Increase in Neurogenic Nitric Oxide Metabolism by Endothelin-1 in Mesenteric Arteries from Hypertensive Rats

2000 ◽  
Vol 36 (5) ◽  
pp. 541-547 ◽  
Author(s):  
Mercedes Ferrer ◽  
M Jesús Alonso ◽  
Mercedes Salaices ◽  
Jesús Marín ◽  
Gloria Balfagón
Keyword(s):  
Nitric Oxide ◽  
Mesenteric Arteries ◽  
Hypertensive Rats ◽  
Endothelin 1 ◽  
Nitric Oxide Metabolism

Catalase activity and expression are reduced in mesenteric arteries from angiotensin II‐infused hypertensive rats

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Kyu‐Tae Kang ◽  
Jennifer C. Sullivan ◽  
Danielle L. Cruthirds ◽  
Jennifer S. Pollock
Keyword(s):  
Angiotensin Ii ◽  
Catalase Activity ◽  
Mesenteric Arteries ◽  
Hypertensive Rats

Vasodilator effect of human adrenomedullin(13 – 52) on hypertensive rats

1995 ◽  
Vol 73 (7) ◽  
pp. 1065-1069 ◽  
Author(s):  
Q. Tian ◽  
D. Zhao ◽  
D. Y. Tan ◽  
Y. T. Zhao ◽  
Q. H. Li ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Angiotensin Ii ◽  
Molecular Mechanisms ◽  
Hypotensive Activity ◽  
Hypertensive Rats ◽  
Hypotensive Action ◽  
Spontaneously Hypertensive ◽  
Endothelin 1 ◽  
In Vitro Effects

Human adrenomedullin (hADM) is a newly isolated peptide with hypotensive activity in normotensive rats. The objective of this study was to investigate the effect of hADM(13–52) on hypertensive animals. hADM(13–52) induced a dose-dependent decrease in the blood pressure of spontaneously hypertensive rats and renal hypertensive rats. This result suggests that hADM is a novel antihypertensive peptide. In isolated rat aortic arteries, hADM(13–52) produced nitric oxide dependent relaxation and inhibited endothelin 1 and angiotensin II release. These in vitro effects may represent the molecular mechanisms underlying the hypotensive action of hADM in vivo.Key words: human adrenomedullin, nitric oxide, endothelin 1, angiotensin II, hypertension.

scholarly journals Upregulation of endothelium-derived hyperpolarizing factor compensates for the loss of nitric oxide in mesenteric arteries of dahl salt-sensitive hypertensive rats

2012 ◽  
Vol 35 (8) ◽  
pp. 849-854 ◽  
Author(s):  
Kenichi Goto ◽  
Yasuo Kansui ◽  
Hideyuki Oniki ◽  
Toshio Ohtsubo ◽  
Kiyoshi Matsumura ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Mesenteric Arteries ◽  
Hypertensive Rats
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