Comparison of three treatment regimens with liposomal amphotericin B (AmBisome®) for visceral leishmaniasis in India: a randomized dose-finding study

Author(s):  
C.P. Thakur ◽  
A.K. Pandey ◽  
G.P. Sinha ◽  
Sobhic Roy ◽  
K. Behbehani ◽  
...  
2021 ◽  
Vol 8 (5) ◽  
pp. 69-72
Author(s):  
Pavankumar Narapaka ◽  
Kalpana Katikala

The complication of visceral leishmaniasis is post-kala-azar dermal leishmaniasis (PKDL). PKDL typically occurs as a result of treatment failure or parasite resistance to treatment regimens, as well as poor patient follow-up. In the treatment of visceral leishmaniasis and post-kala-azar dermal leishmaniasis, Liposomal Amphotericin B is considering as first-line therapy. We're going to show you a case where Liposomal Amphotericin B was used to treat it. Keywords: visceral leishmaniasis, post-kala-azar dermal leishmaniasis, PKDL, kala-azar


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
K. Grabmeier-Pfistershammer ◽  
W. Poeppl ◽  
P. M. Brunner ◽  
K. Rappersberger ◽  
A. Rieger

We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regimens including liposomal amphotericin B, liposomal amphotericin B with miltefosine, liposomal amphotericin B with interferon, and pentamidine combined fluconazole and allopurinol were applied until Leishmania PCR from blood turned negative. This case supports the necessity of multidrug combinational and sequential therapy over a very prolonged period of time in severely immunosuppressed patients infected with Leishmania and highlights the tremendous individual but also economic burden of this disease.


2019 ◽  
Vol 72 ◽  
pp. 101934 ◽  
Author(s):  
Mahmoud Khodabandeh ◽  
Ali Rostami ◽  
Katayoun Borhani ◽  
H. Ray Gamble ◽  
Mohsen Mohammadi

1997 ◽  
Vol 131 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Lucio di Martino ◽  
Robert N. Davidson ◽  
Raffella Giacchino ◽  
Silvestro Scotti ◽  
Francesco Raimondi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document