Chapter 11 Multiple chemical messengers in hypothalamic magnocellular neurons

1986 ◽  
pp. 161-168 ◽  
Author(s):  
Michael J. Brownstein ◽  
Éva Mezey
Physiology ◽  
1988 ◽  
Vol 3 (1) ◽  
pp. 1-5 ◽  
Author(s):  
DE Millhorn ◽  
T Hokfelt

The original concept of chemical neural transmission was based on the assumed principle that individual neurons utilize only one type of neurotransmitter. There is now histological evidence that single nerve cells in both the central and the peripheral nervous system often contain multiple chemical messengers. This article describes the evidence for and the functional significance of multiple messengers in synaptic transmission.


Author(s):  
J. Anthony VanDuzer

SummaryRecently, there has been a proliferation of international agreements imposing minimum standards on states in respect of their treatment of foreign investors and allowing investors to initiate dispute settlement proceedings where a state violates these standards. Of greatest significance to Canada is Chapter 11 of the North American Free Trade Agreement, which provides both standards for state behaviour and the right to initiate binding arbitration. Since 1996, four cases have been brought under Chapter 11. This note describes the Chapter 11 process and suggests some of the issues that may arise as it is increasingly resorted to by investors.


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
T Michel ◽  
A Termentzi ◽  
E Gikas ◽  
M Halabalaki ◽  
AB Smith ◽  
...  

2002 ◽  
Vol 41 (06) ◽  
pp. 233-239 ◽  
Author(s):  
C. Hausteiner ◽  
A. Drzezga ◽  
P. Bartenstein ◽  
M. Schwaiger ◽  
H. Förstl ◽  
...  

SummaryAim: Multiple chemical sensitivity (MCS) is a controversially discussed symptom complex. Patients afflicted by MCS react to very low and generally nontoxic concentrations of environmental chemicals. It has been suggested that MCS leads to neurotoxic damage or neuroimmunological alteration in the brain detectable by positron emission tomography (PET) and single photon emission computer tomography (SPECT). These methods are often applied to MCS patients for diagnosis, although they never proved appropriate. Method: We scanned 12 MCS patients with PET, hypothesizing that it would reveal abnormal findings. Results: Mild glucose hypometabolism was present in one patient. In comparison with normal controls, the patient group showed no significant functional brain changes. Conclusion: This first systematic PET study in MCS patients revealed no hint of neurotoxic or neuroimmuno-logical brain changes of functional significance.


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