Salvage brachytherapy for local recurrence after radical prostatectomy and subsequent external beam radiotherapy

Urology ◽  
2003 ◽  
Vol 62 (6) ◽  
pp. 1068-1072 ◽  
Author(s):  
Andrea Losa ◽  
Luciano Dante Nava ◽  
Nadia Di Muzio ◽  
Paola Mangili ◽  
Barbara Longobardi ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Local Recurrence ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Salvage Brachytherapy

scholarly journals Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Shogo Hosogoe ◽  
Osamu Soma ◽  
Teppei Matsumoto ◽  
Atsushi Imai ◽  
Shingo Hatakeyama ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Local Recurrence ◽  
Ct Scan ◽  
External Beam Radiotherapy ◽  
External Beam Radiation ◽  
External Beam ◽  
Beam Radiation ◽  
Old Japanese ◽  
Salvage Brachytherapy

A 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of prostate cancer and he received postoperative external beam radiation therapy (EBRT) (70 Gy). By May 2008, the PSA dropped to 0.33 ng/mL, and a CT scan showed that the mass had disappeared. On April 2012, the PSA once again rose to 3.1 ng/mL. CT scan and MRI revealed a mass in the prostatic bed. We diagnosed local recurrence of prostate cancer. We underwent salvage low-dose brachytherapy after obtaining informed consent. The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. PSA level rapidly decreased to 0.66 ng/mL by 6 months after seed implantation. No adverse events were seen during the follow-up period.

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