THE PREVENTION OF SPREAD DURING PULMONARY RESECTION BY THE USE OF A DOUBLE-LUMEN CATHETER

We anesthetized, paralyzed, and ventilated 32 dogs. In 16 dogs we measured total pulmonary resistance (RL) during inhalation of acetylcholine (ACh), serotonin (5-HT), and histamine (Hist) aerosols. Cooling both cervical vagi reduced the bronchoconstriction caused by 5-HT 64% (P = 0.001), reduced Hist-induced bronchoconstriction 17% (P = 0.003), and did not significantly reduce bronchoconstriction due to ACh. In seven dogs, we ventilated both lungs separately through a double-lumen catheter. Application of 5-HT to one lung increased the transpulmonary pressure amplitude in the homolateral but not in the contralateral lung. Cooling the homolateral vagus reduced this response 32% (P = 0.02). In nine dogs, we stimulated the peripheral ends of both cut cervical vagi before and during aerosol application of ACh, 5-HT, and Hist. ACh and Hist increased baseline RL 97 and 134%, respectively, without increasing the effect of vagal stimulation. 5-HT increased baseline RL only 27% but greatly augmented the effect of vagal stimulation (mean increase, 271%, P = 0.001). We conclude that 5-HT acts to potentiate vagal effects on airway smooth muscle via the efferent vagal pathway.

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Korelasi antara Letak Ujung Kateter Lumen Ganda Femoralis Jangka Pendek Non-tunneling dengan Laju Aliran darah pada Saat Hemodialisis di RSUP Prof Dr. R. D. Kandou

JURNAL BIOMEDIK (JBM) ◽

10.35790/jbm.10.2.2018.20088 ◽

2018 ◽

Vol 10 (2) ◽

Author(s):

Fery Purba ◽

Richard Sumangkut ◽

Djoni E. Tjandra

Keyword(s):

Renal Failure ◽

Positive Relationship ◽

Scatter Plot ◽

Short Term ◽

Double Lumen ◽

End Stage Renal Failure ◽

Double Lumen Catheter ◽

Lumen Catheter ◽

Tip Position ◽

End Stage

Abstract: Patients with end-stage renal failure are unable to survive without dialysis or renal transplantation. To achieve effective dialysis using a double lumen catheter, placement of the catheter tip plays an important role because it may affect blood flow/Quick of Blood (QB). The selection of femoral vein access is more favorable in critical patients. This study was aimed to obtain the correlation between the tip position of the non-tunneling short-term femoral double lumen catheter (DLC) and QB at the time of hemodialysis. This was an analytical correlative and prospective study with a cross-sectional design in patients with end-stage renal failure undergoing hemodialysis using a non-tunneling short-term femoral DLC. This study was conducted at the Hemodialysis Installation of Prof. Dr. R. D. Kandou Hospital Manado. Data were analyzed by using the Pearson's r test. The results showed that there were 31 patients enrolled in this study. The Pearson’s r test obtained an r of 0.147 (statistically weak) and Sig (2-tailed) of 0.430 which showed no correlation but the scatter plot showed a tendency of a weak positive relationship. Conclusion: There was no significant correlation between Qb and the tip position of DLC, albeit, there was a tendency of a weak positive relationship. Increasing the number of samples will more accurately predict the presence or absence of the correlation between Qb and the tip position of the DLC.Keywords: DLC, QB, hemodialysisAbstrak: Pasien dengan penyakit ginjal stadium akhir tidak dapat mempertahankan hidup tanpa dukungan terapi pengganti ginjal yaitu dialisis atau transplantasi ginjal. Untuk mencapai dialisis yang efektif dengan menggunakan kateter lumen ganda, penempatan kateter berperan penting karena dapat memengaruhi aliran darah/Quick of Blood (QB). Pemilihan akses vena femoralis lebih menguntungkan pada pasien kritis. Penelitian ini bertujuan untuk mengetahui korelasi letak ujung kateter lumen ganda femoralis jangka pendek (DLC) dengan QB pada saat hemodialisis. Jenis penelitian ialah analitik korelatif dan prospektif dengan desain potong lintang. Subyek penelitian ialah pasien dengan gagal ginjal tahap akhir yang menjalani hemodialisis menggunakan kateter lumen ganda femoralis jangka pendek non-tunneling. Penelitian dilakukan di Instalasi Hemodialisis RSUP Prof. Dr. R. D. Kandou, Manado. Data dianalisis menggunakan koefisien korelasi Pearson. Hasil penelitian mendapatkan 31 pasien sebagai subyek. Hasil analisis koefisien Pearson terhadap korelasi antara letak ujung DLC dan QB memperlihatkan hubungan statistik lemah (r = 0,147) dengan Sig (2-tailed) 0,430 yang menunjukkan tidak terdapat hubungan bermakna tetapi pada scatter plot terlihat adanya kecenderungan hubungan positif lemah. Simpulan: Tidak terdapat korelasi bermakna antara Qb dan letak ujung DLC tetapi terdapat kecenderungan hubungan positif lemah. Menambah jumlah sampel akan lebih akurat untuk memrediksi ada tidaknya hubungan antara Qb dan letak ujung DLC. Kata kunci: DLC, laju aliran dara (QB), hemodialisis

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Risk Factors of Catheter-Related Infection in Patients Undergoing Hemodialysis Using Double Lumen Catheter at Dr. M. Djamil Hospital Padang

BioScientia Medicina ◽

10.37275/bsm.v6i1.436 ◽

2021 ◽

Vol 6 (1) ◽

pp. 1292-1299

Author(s):

Muhammad Iqbal ◽

Raflis Rustam ◽

Vendry Rivaldy

Keyword(s):

Risk Factors ◽

Pseudomonas Aeruginosa ◽

Clinical Manifestations ◽

Bloodstream Infections ◽

Sampling Technique ◽

Exit Site ◽

Double Lumen ◽

Exit Site Infection ◽

Double Lumen Catheter ◽

Lumen Catheter

Background. Chronic kidney disease (CKD) is a terminal disease requiring hemodialysis. Hemodialysis requires vascular access using a double lumen catheter (DLC). However, the use of DLC may increase complications mainly infection, either infection of exit site or bloodstream. This study is aimed to seek risk factors contributing to the incidence of central catheter-related infections in CKD patients with DLC undergoing HD at Dr. M. Djamil Hospital, Padang. Methods. This study is a prospective study on patients undergoing HD at Dr. M. Djamil Hospital, Padang. This study using consecutive sampling technique. Data were analyzed using SPSS version 25.0. Results. This study involved 40 CKD patients undergoing HD. Majority of the samples had bloodstream infections (67.5%). Clinical manifestations of purulent secretion, duration of catheter used, and hypoalbuminemia had significant differences in the incidence of DLC infection based on bloodstream infection and exit site infection (p<0.05). The most common bacterial found was Pseudomonas aeruginosa (22.5%) which was sensitive to ceftazidime, cefepime, meropenem, amikacin, gentamicin, ciprofloxacin. Conclusion. Factors contributing to the incidence of DLC-related infections at Dr. M. Djamil Hospital are duration of catheter use and hypoalbuminemia. Pseudomonas aeruginosa is the most common cause of DLC-related infections.

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24.Blood AccessとしてのDouble Lumen Catheterの有効性 : その基礎的検討

JAPANES JOURNAL OF MEDICAL INSTRUMENTATION ◽

10.4286/ikakikaigaku.55.4_196_1 ◽

1985 ◽

Vol 55 (4) ◽

pp. 196

Keyword(s):

Double Lumen ◽

Double Lumen Catheter ◽

Lumen Catheter

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Experimental study on factors affecting the occurrence of malpositioning of the tip of a double lumen catheter against the vessel wall

Nihon Toseki Igakkai Zasshi ◽

10.4009/jsdt.40.851 ◽

2007 ◽

Vol 40 (10) ◽

pp. 851-858

Author(s):

Takehiro Musashi

Keyword(s):

Experimental Study ◽

Vessel Wall ◽

Double Lumen ◽

Factors Affecting ◽

Double Lumen Catheter ◽

Lumen Catheter

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Effect of regional inhomogeneity on collateral airway resistance

Journal of Applied Physiology ◽

10.1152/jappl.1984.57.1.254 ◽

1984 ◽

Vol 57 (1) ◽

pp. 254-261 ◽

Cited By ~ 3

Author(s):

S. D. Fuller ◽

N. E. Robinson

Keyword(s):

Airway Resistance ◽

Transpulmonary Pressure ◽

Double Lumen ◽

Double Lumen Catheter ◽

Lung Segment ◽

Peripheral Airway ◽

Lumen Catheter ◽

Anesthetized Dogs ◽

Relationship Of ◽

Regional Inhomogeneity

We studied the interaction of transpulmonary pressure (Pao) and the pressure in an isolated sublobar lung segment (Ps) on collateral resistance (Rcoll) in excised dog lungs. A double-lumen catheter was advanced through the trachea and wedged in a peripheral airway. Gas flowed through the outer lumenof the catheter (Vcoll) to enter the segment while Ps was measured by the inner lumen. Collateral resistance was calculated as Rcoll = (Ps - Pao)/Vcoll. At constant Ps, raising Pao sharply decreased Rcoll, but at constant Pao, raising Ps increased Rcoll. Replotting these data showed that Rcoll was related to the pressure difference between the segment and the remainder of the lobe (Ps - Pao), such that raising Ps - Pao caused no change in Rcoll at lower Pao but increased Rcoll at higher Pao. Similarfindings occurred in the lungs of closed-chest anesthetized dogs. We propose that this technique measures the sum of resistances of airways and collateral channels found in the segment body (Rs) and of those passing through the segment-lobar parenchymal interface (Ri). Raising Ps - Pao decreases Rs because of the volume dependency of airway resistance and increases Ri due to tissue distortion at the interface occurring as a result of inhomogeneous segment inflation. The net change in measured Rcoll depends on which of its components change in greatest magnitude. This effect varies with Pao due to thehyperbolic relationship of Pao with airway and collateral resistance.

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