RESTRICTION ENZYME ANALYSIS OF HERPES SIMPLEX VIRUS ISOLATES FROM KNOWN CONTACTS OF PATIENTS WITH GENITAL HERPES

The Lancet ◽  
1985 ◽  
Vol 325 (8435) ◽  
pp. 979 ◽  
Author(s):  
IsobelW. Smith ◽  
BeverlyB.B. Barr ◽  
K. Slatford ◽  
D.H.H. Robertson
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Genital Herpes ◽  
Restriction Enzyme ◽  
Enzyme Analysis ◽  
Restriction Enzyme Analysis ◽  
Simplex Virus ◽  
Virus Isolates

Factors affecting recovery of latent herpes simplex virus from human trigeminal ganglia

1982 ◽  
Vol 28 (1) ◽  
pp. 123-129 ◽  
Author(s):  
M. E. Lewis ◽  
K. G. Warren ◽  
V. M. Jeffrey ◽  
T. K. Shnitka
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Surface Area ◽  
Enzyme Analysis ◽  
Restriction Enzyme Analysis ◽  
Trigeminal Ganglia ◽  
Factors Affecting ◽  
Two Factors ◽  
Simplex Virus

The rate of recovery of herpes simplex virus (HSV) from human trigeminal ganglia explant monolayers is affected by two factors: (1) time elapsed from the death of an individual to the establishment of in vitro culture of ganglia and (2) surface area onto which ganglia are explanted. Spontaneous reactivation of HSV from human trigeminal ganglia can be maximized when ganglia are obtained within 12 h of death and explanted onto a surface area of 250 cm2. Viruses isolated by explantation of human trigeminal ganglia were found to be uniformly HSV type 1 by restriction enzyme analysis.

Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management

1996 ◽  
Vol 7 (4) ◽  
pp. 229-232 ◽  
Author(s):  
S E Barton ◽  
P E Munday ◽  
R J Patel
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Genital Herpes ◽  
Genital Tract ◽  
Patient Management ◽  
Sexual Transmission ◽  
Supportive Counselling ◽  
History Of ◽  
Simplex Virus ◽  
The Relationship

A frequent component of the management of patients with genital herpes concerns the possibility of asymptomatic shedding and potential sexual transmission of the virus. Approaches intended to provide supportive counselling and reassurance of patients about these issues need now to be modified in the light of increasing data of the frequency of asymptomatic detection of virus and the effects of antiviral therapy on this phenomenon. Further studies to delineate the relationship between asymptomatic detection of HSV in the genital tract and the mechanism of sexual transmission of this virus need to be conducted before clinicians instigate antiviral suppressive treatment primarily to prevent sexual transmission of HSV. However, it is important that the new data and our greater understanding of the natural history of genital herpes is translated into accurate and comprehensible information for our patients.

Sign in / Sign up

Export Citation Format

Share Document