Monoclonal antibody BR 96 and chemeric monoclonal antibodies having the variable region of MAB BR96 with bind to a variant of LEY antigen on human carcinoma cells

1997 ◽  
Vol 20 (6) ◽  
pp. 480
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
Variable Region ◽  
Carcinoma Cells ◽  
Human Carcinoma ◽  
Ley Antigen

scholarly journals A granulocyte reactive monoclonal antibody, 1G10, identifies the Gal beta 1-4 (Fuc alpha 1-3)GlcNAc (X determinant) expressed in HL-60 cells on both glycolipid and glycoprotein molecules

Blood ◽  
1983 ◽  
Vol 62 (5) ◽  
pp. 1022-1026 ◽  
Author(s):  
DL Urdal ◽  
TA Brentnall ◽  
ID Bernstein ◽  
SI Hakomori
Keyword(s):  
Monoclonal Antibody ◽  
Leukemia Cell ◽  
Promyelocytic Leukemia ◽  
Carcinoma Cells ◽  
Leukemia Cell Line ◽  
Differentiation Antigen ◽  
Human Carcinoma ◽  
Human Granulocytes ◽  
Normal Human ◽  
Promyelocytic Leukemia Cell Line

Abstract 1G10, a monoclonal IgM antibody that identifies a differentiation antigen on human granulocytes and a subpopulation of monocytes, was found to react specifically with glycosphingolipids bearing the Gal beta 1–4(Fuc alpha 1–3)GlcNAc hapten (X determinant). This carbohydrate determinant was found on both glycolipid and glycoprotein molecules isolated from HL-60 cells (a promyelocytic leukemia cell line). Thus, this highly conserved carbohydrate-defined determinant previously described on mouse embryonic and mouse and human carcinoma cells is also expressed as a tissue-specific differentiation antigen on normal human granulocytes.

Ricin A Chain Conjugated With Monoclonal Antibodies Selectively Killing Human Carcinoma Cells In Vitro2

1985 ◽  
Vol 75 (5) ◽  
pp. 831-839 ◽  
Author(s):  
Silvana Canevari ◽  
Rosaria Orlandi ◽  
Marina Ripamonti ◽  
Elda Tagliabue ◽  
Salvatore Aguanno ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Carcinoma Cells ◽  
Ricin A Chain ◽  
Human Carcinoma ◽  
A Chain ◽  
Ricin A

scholarly journals A granulocyte reactive monoclonal antibody, 1G10, identifies the Gal beta 1-4 (Fuc alpha 1-3)GlcNAc (X determinant) expressed in HL-60 cells on both glycolipid and glycoprotein molecules

Blood ◽  
1983 ◽  
Vol 62 (5) ◽  
pp. 1022-1026
Author(s):  
DL Urdal ◽  
TA Brentnall ◽  
ID Bernstein ◽  
SI Hakomori
Keyword(s):  
Monoclonal Antibody ◽  
Leukemia Cell ◽  
Promyelocytic Leukemia ◽  
Carcinoma Cells ◽  
Leukemia Cell Line ◽  
Differentiation Antigen ◽  
Human Carcinoma ◽  
Human Granulocytes ◽  
Normal Human ◽  
Promyelocytic Leukemia Cell Line

1G10, a monoclonal IgM antibody that identifies a differentiation antigen on human granulocytes and a subpopulation of monocytes, was found to react specifically with glycosphingolipids bearing the Gal beta 1–4(Fuc alpha 1–3)GlcNAc hapten (X determinant). This carbohydrate determinant was found on both glycolipid and glycoprotein molecules isolated from HL-60 cells (a promyelocytic leukemia cell line). Thus, this highly conserved carbohydrate-defined determinant previously described on mouse embryonic and mouse and human carcinoma cells is also expressed as a tissue-specific differentiation antigen on normal human granulocytes.

scholarly journals The Aspergillus toxin restrictocin is a suitable cytotoxic agent for generation of immunoconjugates with monoclonal antibodies directed against human carcinoma cells

1989 ◽  
Vol 178 (3) ◽  
pp. 795-802 ◽  
Author(s):  
Francisco P. CONDE ◽  
Rosaria ORLANDI ◽  
Silvana CANEVARI ◽  
Delia MEZZANZANICA ◽  
Marina RIPAMONTI ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Carcinoma Cells ◽  
Cytotoxic Agent ◽  
Human Carcinoma

Delivery of Ricin and Abrin A-Chains to Human Carcinoma Cells in Culture following Covalent Linkage to Monoclonal Antibody LICR-LOND-Fib 75

1984 ◽  
Vol 1 (4) ◽  
pp. 283-292 ◽  
Author(s):  
J.A. FORRESTER ◽  
D.P. McINTOSH ◽  
A.J. CUMBER ◽  
G.D. PARNELL ◽  
W.C.J. ROSS
Keyword(s):  
Monoclonal Antibody ◽  
Carcinoma Cells ◽  
Human Carcinoma ◽  
Covalent Linkage ◽  
Cells In Culture

scholarly journals An IL-15 Superagonist, ALT-803, Enhances Antibody-Dependent Cell-Mediated Cytotoxicity Elicited by the Monoclonal Antibody NEO-201 Against Human Carcinoma Cells

2019 ◽  
Vol 34 (3) ◽  
pp. 147-159 ◽  
Author(s):  
Massimo Fantini ◽  
Justin M. David ◽  
Hing C. Wong ◽  
Christina M. Annunziata ◽  
Philip M. Arlen ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Carcinoma Cells ◽  
Human Carcinoma ◽  
Dependent Cell

Generation and characterization of monoclonal antibodies against plasmin receptor from human carcinoma cells

1994 ◽  
Vol 8 ◽  
pp. 54 ◽  
Author(s):  
R. Lopez-Alemany ◽  
F. Mirshahi ◽  
P. Burtin ◽  
C. Soria ◽  
N. Soria ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Carcinoma Cells ◽  
Human Carcinoma

Mitogenic response of human carcinoma cells to the liver-derived hormone FGF21

2016 ◽  
Vol 11 (03) ◽  
Author(s):  
L Berti ◽  
B Rädle ◽  
HU Häring ◽  
M Hrab((ebrevis)) de Angelis ◽  
H Staiger
Keyword(s):  
Carcinoma Cells ◽  
Mitogenic Response ◽  
Human Carcinoma

Rapid quantification and in situ detection of nitrifying bacteria in biofilms by monoclonal antibody method

2000 ◽  
Vol 41 (4-5) ◽  
pp. 301-308 ◽  
Author(s):  
N. Noda ◽  
H. Ikuta ◽  
Y. Ebie ◽  
A. Hirata ◽  
S. Tsuneda ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Monoclonal Antibodies ◽  
Fluorescent Antibody ◽  
Nitrifying Bacteria ◽  
Fluorescent Antibody Technique ◽  
Antibody Technique ◽  
Antibody Method ◽  
In Situ Detection ◽  
Rapid Quantification

Fluorescent antibody technique by the monoclonal antibody method is very useful and helpful for the rapid quantification and in situ detection of the specific bacteria like nitrifiers in a mixed baxterial habitat such as a biofilm. In this study, twelve monoclonal antibodies against Nitrosomonas europaea (IFO14298) and sixteen against Nitrobacter winogradskyi (IFO14297) were raised from splenocytes of mice (BALB/c). It was found that these antibodies exhibited little cross reactivity against various kinds of heterotrophic bacteria. The direct cell count method using monoclonal antibodies could exactly detect and rapidly quantify N. europaea and N. winogradskyi. Moreover, the distribution of N. europaea and N. winogradskyi in a biofilm could be examined by in situ fluorescent antibody technique. It was shown that most of N. winogradskyi existed near the surface part and most of N. europaea existed at the inner part of the polyethylene glycol (PEG) gel pellet, which had entrapped activated sludge and used in a landfill leachate treatment reactor. It was suggested that this monoclonal antibody method was utilized for estimating and controlling the population of nitrifying bacteria as a quick and favorable tool.

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