Localization of human herpesvirus type 8 (HHV-8) in the Kaposi's sarcoma tissues and the semen specimens of HIV-1 infected and uninfected individuals by utilizing in situ polymerase chain reaction

1998 ◽  
Vol 41 (1-2) ◽  
pp. 149-160 ◽  
Author(s):  
Lisa Bobroski ◽  
Alexander U. Bagasra ◽  
Deepa Patel ◽  
P. Saikumari ◽  
Matthew Memoli ◽  
...  
1995 ◽  
Vol 47 (1) ◽  
pp. 65-69 ◽  
Author(s):  
F. Wilborn ◽  
C. A. Schmidt ◽  
F. Lorenz ◽  
R. Peng ◽  
H. Gelderblom ◽  
...  

1996 ◽  
Vol 61 (4) ◽  
pp. 662-664 ◽  
Author(s):  
Christian Andreas Schmidt ◽  
Freimut Wilborn ◽  
Katja Weiss ◽  
Volker Brinkmann ◽  
Helmut Oettle ◽  
...  

AIDS ◽  
2000 ◽  
Vol 14 (8) ◽  
pp. 913-919 ◽  
Author(s):  
Marina Núñez ◽  
Ana Machuca ◽  
Vincent Soriano ◽  
Daniel Podzamczer ◽  
Juan González-Lahoz

2013 ◽  
Vol 88 (2) ◽  
pp. 243-246 ◽  
Author(s):  
Patricia Fonseca Pereira ◽  
Tullia Cuzzi ◽  
Maria Clara Gutierrez Galhardo

Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis. The aim of this study is to confirm that immunohistochemistry is a valuable tool for differentiating KS from its simulators in skin biopsies of HIV patients. Immunohistochemical and histological analyses were performed in 49 Kaposi's sarcoma skin biopsies and 60 of its histological simulators. Positivity was present in the 49 Kaposi's sarcoma skin biopsies and no staining was observed in the 60 simulators analyzed, resulting in sensibility and specificity of 100%. HHV-8 immunohistochemical detection is an effective tool for diagnosing Kaposi's sarcoma, especially in early lesions in which neoplastic features are not evident. It also contributes to its histological differential diagnosis.


1992 ◽  
Vol 6 (3) ◽  
pp. 215-221 ◽  
Author(s):  
B. Delord ◽  
M. Ottmann ◽  
M.-H. Schrive ◽  
J.-M. Ragnaud ◽  
J.-M. Seigneurin ◽  
...  

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