SP-0628: What is our target after complex skin reconstruction?

2020 ◽  
Vol 152 ◽  
pp. S352
Keyword(s):  
2007 ◽  
Vol 121 (6) ◽  
pp. 511-515 ◽  
Author(s):  
P. Lefèvre ◽  
S. Van Sint Jan ◽  
J. P. Beauthier ◽  
M. Rooze
Keyword(s):  

2019 ◽  
Vol 5 (2) ◽  
pp. 4-8
Author(s):  
Humberto Miguel Pontillo ◽  
◽  
Jhorbet C. Rodríguez Castillo ◽  
Tolentino Dos Santos ◽  

!Objective: The penile cancer is a rare entity in the developed countries and its incidence increases in the developing countries, achieving up to 10% of the malignancies in men. There is a crucial association with the HPV, in the same way it relates to inadequate hygiene habits and the phimosis. The objective of the surgical treatment is resection with adequate margins, and the inguinal lymph node dissection when indicated. The restore skin coverage in these lesions is a challenge for the surgeon, as it seeks to achieve a phallus almost normal appearance, and restore the patient's tactile and the erogenous function, with the fewest possible interventions, trying to minimize the psychological trauma. Previously, many of these patients were considered inoperable and were recommended to radiation therapy to cure the injury. The evolution of the plastic surgical techniques using skin or the myocutaneous flaps, have provided the surgeon another option to keep the local oncological control with acceptable morbidity. Clinical Case: The aim of this paper is to present the case of a 56 years old male patient with diagnostic of squamous cell cancer of the penis stage II, who underwent the penile stripping, with bilateral inguinal lymphadenectomy; and rotation flap reconstruction of the scrotal skin. We found no published paper about the skin reconstruction of penile skin flap from scrotum for cancer patients, hence the importance of this work. Keywords: Cancer, Penile, HPV, Reconstruction, Faloplastia.


2014 ◽  
Vol 10 (3) ◽  
pp. 87-91
Author(s):  
Fathy Shoeib ◽  
Sleiman Gebran ◽  
Muna Alshihi ◽  
Mokhtar Hassan ◽  
Shahid Abdulrashid ◽  
...  

Author(s):  
Inge J. Veldhuizen ◽  
Philip Brouwer ◽  
Abdullah Aleisa ◽  
Nicholas R. Kurtansky ◽  
Stephen W. Dusza ◽  
...  

2019 ◽  
Vol 11 ◽  
pp. 81-87 ◽  
Author(s):  
Hajime Matsumine ◽  
Hiroshi Fujimaki ◽  
Mika Takagi ◽  
Satoko Mori ◽  
Tomohiro Iwata ◽  
...  

2018 ◽  
Vol 59 (3-4) ◽  
pp. 242-254 ◽  
Author(s):  
Florian S.  Frueh ◽  
Nadia Sanchez-Macedo ◽  
Maurizio Calcagni ◽  
Pietro Giovanoli ◽  
Nicole Lindenblatt

Background: The treatment of extensive skin defects and bradytrophic wounds remains a challenge in clinical practice. Despite emerging tissue engineering approaches, skin grafts and dermal substitutes are still the routine procedure for the majority of skin defects. Here, we review the role of vascularization and lymphangiogenesis for skin grafting and dermal substitutes from the clinician’s perspective. Summary: Graft revascularization is a dynamic combination of inosculation, angiogenesis, and vasculogenesis. The majority of a graft’s microvasculature regresses and is replaced by ingrowing microvessels from the wound bed, finally resulting in a chimeric microvascular network. After inosculation within 48–72 h, the graft is re-oxygenated. In contrast to skin grafts, the vascularization of dermal substitutes is slow and dependent on the ingrowth of vessel-forming angiogenic cells. Preclinical angiogenic strategies with adipose tissue-derived isolates are appealing for the treatment of difficult wounds and may markedly accelerate skin reconstruction in the future. However, their translation from bench to bedside is still restricted by major regulatory restrictions. Finally, the lymphatic system contributes to edema reduction and the removal of local wound debris. Therapeutic lymphangiogenesis is an emerging field of research in skin reconstruction. Key Messages: For the successful engraftment of skin grafts and dermal substitutes, the rapid formation of a microvascular network is of pivotal importance. Hence, to understand the biological processes behind revascularization of skin substitutes and to implement this knowledge into clinical practice is a prerequisite when treating skin defects. Furthermore, a functional lymphatic drainage crucially contributes to the engraftment of skin substitutes.


2019 ◽  
Vol 14 (6) ◽  
pp. 065005 ◽  
Author(s):  
Yuliya Nashchekina ◽  
Igor Samusenko ◽  
Ivan Zorin ◽  
Lubov Kukhareva ◽  
Alexander Bilibin ◽  
...  

2003 ◽  
Vol 16 (04) ◽  
pp. 255-259 ◽  
Author(s):  
M. A. Stanley ◽  
R. A. S. White ◽  
D. M. Anderson

SummaryA seven month old female Yorkshire Terrier was admitted with severe contracture and scarring of the ventral abdomen, thorax and limbs, after a scald injury. Surgical management consisted of multiple releasing and reconstruction skin flaps. Keratinocytes, harvested from a 1 cm2 full thickness skin biopsy, were cultured on a lawn of irradiated feeder cells, and used as a cultured epithelial autograft on the remaining skin deficits. Epithelialisation of the deficits was complete at the first dressing change, five days after application. This is the first report of successful culture of canine keratinocytes suitable for use in skin reconstruction in a clinical case.


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