Damaged interlobular bile ducts in primary biliary cirrhosis show reduced expression of glutathione-S-transferase-pi and aberrant expression of 4-hydroxynonenal

2002 ◽  
Vol 37 (2) ◽  
pp. 176-183 ◽  
Author(s):  
Koichi Tsuneyama ◽  
Kenichi Harada ◽  
Naoko Kono ◽  
Motoko Sasaki ◽  
Takahito Saito ◽  
...  
1999 ◽  
Vol 54 (5) ◽  
pp. 165-168 ◽  
Author(s):  
Bruno Cupertino Migueletto ◽  
Abrahão Elias Hallack Neto ◽  
Elaine Zamora Domingues ◽  
Pedro Paulo Neves de Castro ◽  
Hartmut Stocker ◽  
...  

Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases.


1981 ◽  
Vol 12 (9) ◽  
pp. 782-793 ◽  
Author(s):  
Dominique Bernuau ◽  
Gérard Feldmann ◽  
Claude Degott ◽  
Christian Gisselbrecht

2005 ◽  
Vol 205 (4) ◽  
pp. 451-459 ◽  
Author(s):  
Motoko Sasaki ◽  
Hiroko Ikeda ◽  
Hironori Haga ◽  
Toshiaki Manabe ◽  
Yasuni Nakanuma

2010 ◽  
Vol 138 (5) ◽  
pp. S-807
Author(s):  
Toru Takahashi ◽  
Tomofumi Miura ◽  
Junichiro Nakamura ◽  
Satoshi Yamada ◽  
Tsutomu Miura ◽  
...  

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