627 Potential role of cytokine gene polymorphisms in hepatitis B infection outcome

2005 ◽  
Vol 42 ◽  
pp. 230
Gene ◽  
2014 ◽  
Vol 544 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Dongxiang Pan ◽  
Xiaoyun Zeng ◽  
Hongping Yu ◽  
Yan Yang ◽  
Chunhua Bei ◽  
...  

2003 ◽  
Vol 98 (1) ◽  
pp. 144-150 ◽  
Author(s):  
Ziv Ben-Ari ◽  
Eytan Mor ◽  
Orit Papo ◽  
Batia Kfir ◽  
Jaqueline Sulkes ◽  
...  

2008 ◽  
Vol 23 (5) ◽  
pp. 783-789 ◽  
Author(s):  
Henry L-Y Chan ◽  
Ada M-L Tse ◽  
Angel M-L Chim ◽  
Vincent W-S Wong ◽  
Paul C-L Choi ◽  
...  

2007 ◽  
Vol 13 (2) ◽  
pp. 253-255 ◽  
Author(s):  
A Amirzargar ◽  
F Khosravi ◽  
S Dianat ◽  
F Hushmand ◽  
P Maryousef ◽  
...  

Background Cytokine gene polymorphisms have been extensively studied in association with different diseases. The role of cytokine gene polymorphisms in multiple sclerosis (MS), as a chronic immune-mediated neurodegenerative disease, has been previously reported. Materials and methods DNA samples were collected from 44 patients with relapsing-remitting multiple sclerosis (RRMS) and 140 unrelated healthy subjects. All participants in this study were matched for ethnicity. Cytokine gene SNPs were determined using the PCR-SSP method. Results and discussion We found no significant differences between MS patients and controls in most of the studied cytokine genes. Remarkable results were obtained for IL-2 GG —330 genotype (P = 0.06), IL-6 C —174 allele (P = 0.06), CG and GG genotypes (P < 0.001), and GG (P = 0.02) and CG (P < 0.001) haplotypes, and TNF-α A —238 allele (P < 0.001), GG (P = 0.003) and GA (P < 0.001) haplotypes. These results suggest that polymorphic variations of these pro-inflammatory cytokines play an important role in susceptibility to MS. Multiple Sclerosis 2007; 13: 253–255. http://msj.sagepub.com


2001 ◽  
Vol 7 (3) ◽  
pp. 255-263 ◽  
Author(s):  
Julie R. Jonsson ◽  
Cui Hong ◽  
David M. Purdie ◽  
Carmel Hawley ◽  
Nicky Isbel ◽  
...  

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