The μ-opioid receptor gene-dose dependent reductions in G-protein activation in the pons/medulla and antinociception induced by endomorphins in μ-opioid receptor knockout mice

Neuroscience ◽  
1999 ◽  
Vol 94 (1) ◽  
pp. 203-207 ◽  
Author(s):  
H Mizoguchi ◽  
M Narita ◽  
D.E Oji ◽  
C Suganuma ◽  
H Nagase ◽  
...  
Keyword(s):  
G Protein ◽  
Opioid Receptor ◽  
Knockout Mice ◽  
Receptor Gene ◽  
Protein Activation ◽  
Gene Dose ◽  
G Protein Activation ◽  
Μ Opioid Receptor ◽  
Pons Medulla ◽  
Dose Dependent

Loss of μ-opioid receptor-mediated G-protein activation in the pons/medulla of mice lacking the exons 2 and 3 of μ-opioid receptor gene

2002 ◽  
Vol 335 (2) ◽  
pp. 91-94 ◽  
Author(s):  
Hirokazu Mizoguchi ◽  
Hsiang-En Wu ◽  
Minoru Narita ◽  
Horace H. Loh ◽  
Hiroshi Nagase ◽  
...  
Keyword(s):  
G Protein ◽  
Opioid Receptor ◽  
Receptor Gene ◽  
Protein Activation ◽  
G Protein Activation ◽  
Μ Opioid Receptor ◽  
Pons Medulla

scholarly journals Absence of G-protein activation by μ-opioid receptor agonists in the spinal cord of μ-opioid receptor knockout mice

1999 ◽  
Vol 126 (2) ◽  
pp. 451-456 ◽  
Author(s):  
Minoru Narita ◽  
Hirokazu Mizoguchi ◽  
Michiko Narita ◽  
Ichiro Sora ◽  
George R Uhl ◽  
...  
Keyword(s):  
Spinal Cord ◽  
G Protein ◽  
Opioid Receptor ◽  
Knockout Mice ◽  
Protein Activation ◽  
Receptor Agonists ◽  
G Protein Activation ◽  
Μ Opioid Receptor ◽  
Opioid Receptor Agonists

Up-regulation of μ-opioid receptor-mediated G-protein activation in protein kinase Cγ knockout mice following repeated naloxone treatment

2003 ◽  
Vol 338 (2) ◽  
pp. 103-106 ◽  
Author(s):  
Minoru Narita ◽  
Masami Suzuki ◽  
Hirokazu Mizoguchi ◽  
Michiko Narita ◽  
Yoshinori Yajima ◽  
...  
Keyword(s):  
Protein Kinase ◽  
G Protein ◽  
Opioid Receptor ◽  
Knockout Mice ◽  
Protein Activation ◽  
G Protein Activation ◽  
Μ Opioid Receptor ◽  
Naloxone Treatment

scholarly journals Live Cell Monitoring of μ-Opioid Receptor-mediated G-protein Activation Reveals Strong Biological Activity of Close Morphine Biosynthetic Precursors

2007 ◽  
Vol 282 (37) ◽  
pp. 27126-27132 ◽  
Author(s):  
Viacheslav O. Nikolaev ◽  
Chotima Boettcher ◽  
Christian Dees ◽  
Moritz Bünemann ◽  
Martin J. Lohse ◽  
...  
Keyword(s):  
Biological Activity ◽  
G Protein ◽  
Opioid Receptor ◽  
Live Cell ◽  
Protein Activation ◽  
G Protein Activation ◽  
Cell Monitoring ◽  
Μ Opioid Receptor

Blockade of μ-opioid receptor-mediated G-protein activation and antinociception by TRK-820 in mice

2003 ◽  
Vol 461 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Hirokazu Mizoguchi ◽  
Kuei-chun Hung ◽  
Randy Leitermann ◽  
Minoru Narita ◽  
Hiroshi Nagase ◽  
...  
Keyword(s):  
G Protein ◽  
Opioid Receptor ◽  
Protein Activation ◽  
G Protein Activation ◽  
Μ Opioid Receptor

Agonists determine the pattern of G-protein activation in μ-opioid receptor-mediated supraspinal analgesia

2001 ◽  
Vol 54 (2) ◽  
pp. 229-235 ◽  
Author(s):  
Pilar Sánchez-Blázquez ◽  
Pilar Gómez-Serranillos ◽  
Javier Garzón
Keyword(s):  
G Protein ◽  
Opioid Receptor ◽  
Protein Activation ◽  
G Protein Activation ◽  
Μ Opioid Receptor
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