Automated Detection and Characterization of Multiple Sclerosis Lesions in Brain MR Images

1998 ◽  
Vol 16 (3) ◽  
pp. 311-318 ◽  
Author(s):  
D Goldberg-Zimring ◽  
A Achiron ◽  
S Miron ◽  
M Faibel ◽  
H Azhari
Author(s):  
Amina Merzoug ◽  
Nacéra Benamrane ◽  
Abdelmalik Taleb-Ahmed

This paper presents a segmentation method to detect multiple sclerosis (MS) lesions in brain MRI based on the artificial immune systems (AIS) and a support vector machines (SVM). In the first step, AIS is used to segment the three main brain tissues white matter, gray matter, and cerebrospinal fluid. Then the features were extracted and SVM is applied to detect the multiple sclerosis lesions based on SMO training algorithm. The experiments conducted on 3D brain MR images produce satisfying results.


2002 ◽  
Vol 58 (3) ◽  
pp. 399-405 ◽  
Author(s):  
RYUJIRO YOKOYAMA ◽  
YONGBUM LEE ◽  
TAKESHI HARA ◽  
HIROSHI FUJITA ◽  
TAKAHIKO ASANO ◽  
...  

2015 ◽  
Vol 15 (02) ◽  
pp. 1540024 ◽  
Author(s):  
M. KAYALVIZHI ◽  
K. R. ANANDH ◽  
G. KAVITHA ◽  
C. M. SUJATHA ◽  
S. RAMAKRISHNAN

In this work, an attempt is made to analyze anatomical regions of Alzheimer's brain MR images using level set and Minkowski functionals (MFs). The T1 weighted sagittal view of normal and abnormal images considered in this work, are obtained from MIRIAD database. The ventricle along with the hippocampus is segmented using Reaction Diffusion (RD) level set method and is subjected to further analysis using MFs. The prominent feature derived from the segmented region which contains ventricle and hippocampus is correlated with the Mini-Mental State Examination (MMSE) score. Results show that RD method is able to delineate the exact boundary of the ventricle along with hippocampus. It is observed that the MF-area of segmented region provides better discrimination of normal and abnormal subjects (p < 0.001) compared to the MF-perimeter and MF-Euler number. The correlation of the MMSE with prominent MF-area for normal, mild, moderate and severe are found to be 0.71, 0.82, 0.84 and 0.89, respectively. This suggests that characterization of brain structures using MFs improve the discrimination capability of brain disorders. Hence MF-area feature could be used for the study of progression in Alzheimer's disease (AD) like neurodegenerative disorders.


1991 ◽  
Vol 15 (3) ◽  
pp. 359-364 ◽  
Author(s):  
Guy Wilms ◽  
Guy Marchal ◽  
Eric Kersschot ◽  
Piet Vanhoenacker ◽  
Philippe Demaerel ◽  
...  

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