High-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography–tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(02)00480-6 ◽

2003 ◽

Vol 30 (5) ◽

pp. 1459-1467 ◽

Author(s):

Samuel A Testino ◽

Gabor Patonay

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Human Cytochrome ◽

Liquid Chromatography Tandem Mass

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A high-throughput inhibition screening of major human cytochrome P450 enzymes using anin vitrococktail and liquid chromatography-tandem mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.3003 ◽

2013 ◽

Vol 28 (2) ◽

pp. 197-203 ◽

Author(s):

Chong-Zhen Qin ◽

Xian Ren ◽

Zhi-Rong Tan ◽

Yao Chen ◽

Ji-Ye Yin ◽

...

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

High Throughput ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Human Cytochrome ◽

Liquid Chromatography Tandem Mass

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A High-Throughput Assay Using Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous In Vivo Phenotyping of 5 Major Cytochrome P450 Enzymes in Patients

Therapeutic Drug Monitoring ◽

10.1097/ftd.0b013e318197e1bf ◽

2009 ◽

Vol 31 (2) ◽

pp. 239-246 ◽

Author(s):

Sussan Ghassabian ◽

Manoranjenni Chetty ◽

Bruce N Tattam ◽

MRACI C Chem ◽

John Glen ◽

...

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

High Throughput Assay

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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development for screening of potential tamoxifen-drug/herb interaction via in vitro cytochrome P450 inhibition assay

Journal of Chromatography B ◽

10.1016/j.jchromb.2020.122148 ◽

2020 ◽

Vol 1148 ◽

pp. 122148

Author(s):

Y.F. Yong ◽

S.C. Tan ◽

Mervyn W.O. Liew ◽

N.S. Yaacob

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Method Development ◽

Tandem Mass ◽

Inhibition Assay ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography–tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2007.01.006 ◽

2007 ◽

Vol 852 (1-2) ◽

pp. 128-137 ◽

Author(s):

Xiaoyan Li ◽

Xiaoyan Chen ◽

Qiang Li ◽

Linling Wang ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Sub one minute inhibition assays for the major cytochrome P450 enzymes utilizing ultra-performance liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3465 ◽

2008 ◽

Vol 22 (9) ◽

pp. 1345-1350 ◽

Author(s):

Paul D. Rainville ◽

Jessalynn P. Wheaton ◽

Peter G. Alden ◽

Robert S. Plumb

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Ultra Performance Liquid Chromatography ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Validated liquid chromatography–tandem mass spectrometry method for determination of totally nine probe metabolites of cytochrome P450 enzymes and UDP-glucuronosyltransferases

Talanta ◽

10.1016/j.talanta.2012.12.023 ◽

2013 ◽

Vol 106 ◽

pp. 220-228 ◽

Author(s):

Jr-Ting Lee ◽

Li-Heng Pao ◽

Cheng-Huei Hsiong ◽

Pei-Wei Huang ◽

Tung-Yuan Shih ◽

...

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays

Drug Metabolism Letters ◽

10.2174/1872312810666161124143522 ◽

2017 ◽

Vol 10 (4) ◽

pp. 264-269 ◽

Author(s):

Siva Putluru ◽

Murali Matta ◽

Deepak Ahire ◽

Murali Subramanian ◽

Michael Sinz ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Enzyme Assays ◽

Tandem Mass ◽

Spectrometry Method ◽

Mass Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Precolumn derivatization of cysteine residues for quantitative analysis of five major cytochrome P450 isoenzymes by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3202 ◽

2007 ◽

Vol 21 (20) ◽

pp. 3234-3244 ◽

Author(s):

Xiaotao Duan ◽

Xiaoyan Chen ◽

Yiming Yang ◽

Dafang Zhong

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Quantitative Analysis ◽

Tandem Mass Spectrometry ◽

Cysteine Residues ◽

Precolumn Derivatization ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry

Chemical Research in Toxicology ◽

10.1021/acs.chemrestox.1c00346 ◽

2021 ◽

Author(s):

Kexin Li ◽

Zehua Li ◽

Jianfeng Wu ◽

Ying Gong ◽

Lei Guo ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Damage Effect ◽

Tandem Mass ◽

Nitrogen Mustards ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8060 ◽

2018 ◽

Vol 32 (6) ◽

pp. 480-488 ◽

Author(s):

Wenchao Sun ◽

Khoa Dinh Nguyen ◽

William L. Fitch ◽

Samuel D. Banister ◽

Hongxiang Tang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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