scholarly journals A NOVEL SCORING SYSTEM FOR PREDICTION OF CARDIAC SYNDROME X IN WOMEN WITH TYPICAL ANGINA AND POSITIVE EXERCISE TOLERANCE TEST: IMPLICATIONS FOR NON-INVASIVE IMAGING

2015 ◽  
Vol 65 (10) ◽  
pp. A1621 ◽  
Author(s):  
Farzad Masoudkabir ◽  
Ali Vasheghani-Farahani ◽  
Seyed Ebrahim Kassaian
Keyword(s):  
Scoring System ◽  
Exercise Tolerance ◽  
Tolerance Test ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Non Invasive ◽  
Exercise Tolerance Test ◽  
Cardiac Syndrome

scholarly journals Cardiac syndrome X – a challenge for Cardiologist

1970 ◽  
Vol 6 (1) ◽  
pp. 32-34
Author(s):  
Nilufar Fatema ◽  
KMHS Sirajul Haque ◽  
Md Abu Siddique ◽  
Sajal Banerjee ◽  
Fazlur Rahman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Angina Pectoris ◽  
Coronary Arteries ◽  
Exercise Tolerance ◽  
Tolerance Test ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Exercise Tolerance Test ◽  
Cardiac Syndrome

Cardiac syndrome X is a multifactorial disorder. A triad of angina pectoris, positive exercise tolerance test (ETT) and angiographically normal epicardial coronary arteries, is called Cardiac syndrome X. Though the normal epicardial coronary arteries, patients present with debilitating chest pain which increases morbidity and poor quality of life. The particular cause of Cardiac syndrome X is still unknown. Many large trails are on going to detect exact pathogenesis of this condition. A multiple treatment regimens may reduce the morbidity and improve the quality of life of these patients. Key words: Angina pectoris; exercise tolerance test. DOI: 10.3329/uhj.v6i1.7188University Heart Journal Vol.6(1) 2010 pp.32-34

scholarly journals Novel Scoring System for Prediction of Cardiac Syndrome X in Women with Typical Angina and a Positive Exercise Tolerance Test

2018 ◽  
Vol 45 (1) ◽  
pp. 5-10 ◽  
Author(s):  
Farzad Masoudkabir ◽  
Ali Vasheghani-Farahani ◽  
Elham Hakki ◽  
Hamidreza Poorhosseini ◽  
Saeed Sadeghian ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Scoring System ◽  
Degrees Of Freedom ◽  
Obstructive Coronary Artery Disease ◽  
Area Under The Curve ◽  
Tolerance Test ◽  
Exercise Tolerance Test ◽  
Cardiac Syndrome ◽  
Artery Disease

A major diagnostic challenge for cardiologists is to distinguish cardiac syndrome X (CSX) from obstructive coronary artery disease in women with typical angina and a positive exercise tolerance test (ETT). We performed this study to develop a scoring system that more accurately predicts CSX in this patient population. Data on 976 women with typical angina and a positive ETT who underwent coronary angiography at our center were randomly divided into derivation and validation datasets. We developed a backward stepwise logistic regression model that predicted the presence of CSX, and a scoring system was derived from it. The derivation dataset (809 patients) was calibrated by uing a Hosmer-Lemeshow goodness-of-fit test (8 degrees of freedom; χ2=12.9; P=0.115), and the area under the curve was 0.758. The validation dataset (167 patients) was calibrated in the same way (8 degrees of freedom; χ2=9.0; P=0.339), and the area under the curve was 0.782. Independent predictors of CSX were age <55 years; negative histories of smoking, diabetes mellitus, hyperlipidemia, hypertension, or familial premature coronary artery disease; and highly positive ETTs. A total score >9.5 was the optimal cutoff point for differentiating CSX from obstructive coronary artery disease. Our proposed scoring system is a simple, objective, and accurate system for distinguishing CSX from obstructive coronary artery disease in women with typical angina and positive ETTs. It may help determine which of these patients need invasive coronary angiograms or noninvasive tests like computed tomographic coronary angiography.

EXERCISE TOLERANCE TESTS IN THE DIAGNOSIS OF CORONARY HEART DISEASE, TESTING OF PATIENTS WITH MYOCARDIAL INFARCTION AND REVASCULARIZATION

2021 ◽  
Vol 5 (1) ◽  
pp. 1247-1256
Author(s):  
L. Ushakova ◽  
◽  
E. Vertinsky ◽  
M. Shtonda ◽  
I. Semenenkov ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Exercise Tolerance ◽  
Tolerance Test ◽  
Bicycle Ergometry ◽  
Non Invasive ◽  
Exercise Tolerance Test ◽  
Disease Testing

Exercise tolerance test is one of the most commonly used non-invasive cardiac tests used to diagnose coronary heart disease, determine prognosis, and evaluate treatment. Treadmill test or bicycle ergometry allows determining how much more expensive and complex follow-up examination is necessary for the patient: myocardial perfusion scintigraphy with stress, stress echocardiography, multispiral computed tomography, as well as defining more clearly the indications for coronary angiography. The article presents modern ideas about a differentiated approach to performing exercise tolerance tests in patients with coronary heart disease, myocardial infarction, and revascularization.

Serum bilirubin predicts long-term clinical outcomes in patients with cardiac syndrome X

Heart ◽  
2010 ◽  
Vol 96 (15) ◽  
pp. 1227-1232 ◽  
Author(s):  
S.-S. Huang ◽  
P.-H. Huang ◽  
H.-B. Leu ◽  
T.-C. Wu ◽  
S.-J. Lin ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Serum Bilirubin ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome

Effects of combination of statin and calcium channel blocker in patients with cardiac syndrome X

2014 ◽  
Vol 25 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Xinling Zhang ◽  
Qiang Li ◽  
Jing Zhao ◽  
Xiangting Li ◽  
Xiaofei Sun ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blocker ◽  
Channel Blocker ◽  
Syndrome X ◽  
Cardiac Syndrome X ◽  
Cardiac Syndrome

scholarly journals Relationship Between High Sensitivity C-reactive Protein and CagA Positive Helicobacter pylori in Cardiac Syndrome X

2013 ◽  
Vol 5 (3) ◽  
pp. 527-533
Author(s):  
Y. Rasmi ◽  
M. H. Seyed-Mohammadzad ◽  
S. Raeisi
Keyword(s):  
High Sensitivity ◽  
Syndrome X ◽  
C Reactive Protein ◽  
Cardiac Syndrome X ◽  
Elisa Method ◽  
Reactive Protein ◽  
Cardiac Syndrome ◽  
Cytotoxin Associated Gene A ◽  
Hs Crp ◽  
Caga Status

Cytotoxin-associated gene A (CagA) may induce a persistent systemic inflammatory response in cardiac syndrome X (CSX). We aimed to evaluate relationship of CagA status and high sensitivity C-reactive protein (hs-CRP) in CSX patients. Sixty CSX patients and 60 gender matched controls were enrolled. Plasma samples were tested in terms of the presence of IgG antibody to Helicobacterpylori (anti-H. pylori) and CagA (anti-CagA) using ELISA method. Also, plasma level of hs-CRP was measured by ELISA method. CSX patients were detected to have significantly higher plasma hs-CRP level in comparison with the control ones (3.64 ± 3.07 vs. 0.54 ± 0.49, µg/ml, P = 0.0001). Plasma levels of hs-CRP in CSX patients with anti-CagA+ were significantly higher than those in anti-CagA(-) (CSX: 4.66±3.63 vs. 2.58±1.95 µg/ml, P = 0.011). Also, plasma levels of hs-CRP in the controls with anti-CagA+ were significantly higher than those in anti-CagA- (1.05±0.68 vs. 0.32±0.31 µg/ml, respectively, P = 0.004). The present data suggested that CagA status was probably associated with susceptibility to severe CSX by causing inflammation. The evidence for this hypothesis indicated that levels of hs-CRP increased in anti-CagA+ patients compared to the anti-CagA- ones. Keywords: Cardiac syndrome X; Helicobacter pylori; Inflammation ; hs-CRP, Cytotoxin-associated gene A. © 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v5i3.14171 J. Sci. Res. 5 (3), 527-533 (2013)

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