Delineation of contiguous determinants essential for biological functions of the pre-S sequence of the hepatitis B virus envelope protein: Its antigenicity, immunogenicity and cell-receptor recognition

1988 ◽  
Vol 139 ◽  
pp. 13-38 ◽  
Author(s):  
A.R. Neurath ◽  
S.B.H. Kent ◽  
N. Strick ◽  
K. Parker
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Envelope Protein ◽  
Cell Receptor ◽  
Biological Functions ◽  
Virus Envelope ◽  
B Virus ◽  
Receptor Recognition ◽  
Virus Envelope Protein

Role of Glycan Processing in Hepatitis B Virus Envelope Protein Trafficking

1998 ◽  
pp. 207-216 ◽  
Author(s):  
Timothy M. Block ◽  
Xuanyong Lu ◽  
Anand Mehta ◽  
Jason Park ◽  
Baruch S. Blumberg ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Protein Trafficking ◽  
Envelope Protein ◽  
Virus Envelope ◽  
B Virus ◽  
Virus Envelope Protein

scholarly journals Determination of the Minimal Distance between the Matrix and Transmembrane Domains of the Large Hepatitis B Virus Envelope Protein

2005 ◽  
Vol 79 (12) ◽  
pp. 7918-7921 ◽  
Author(s):  
Britta Kluge ◽  
Michaela Schläger ◽  
Alexander Pairan ◽  
Volker Bruss
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Envelope Protein ◽  
Transmembrane Domain ◽  
Minimal Distance ◽  
Virus Envelope ◽  
B Virus ◽  
The Matrix ◽  
Virus Envelope Protein ◽  
Virion Formation

ABSTRACT The cytosolic matrix domain (MD) located between amino acids (aa) 103 and 124 of the large hepatitis B virus envelope protein L is essential for virion formation. We reduced the distance between MD and the transmembrane domain (TD; aa 254 to 272) by deletions starting at aa 132. Six mutants with deletions of up to aa 234 were wild type, and four mutants with slightly larger deletions were blocked with respect to virion morphogenesis. Thus, the minimal distance between MD and TD was around 26 aa. This spacer might be required by MD to reach contact sites on the capsid.

Characterization of monoclonal antibodies specific for the pre-S2 region of the hepatitis B virus envelope protein

1986 ◽  
Vol 23 (9) ◽  
pp. 991-997 ◽  
Author(s):  
A.R. Neurath ◽  
P. Adamowicz ◽  
S.B.H. Kent ◽  
M.M. Riottot ◽  
N. Strick ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Envelope Protein ◽  
Virus Envelope ◽  
B Virus ◽  
Virus Envelope Protein
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