Preservation and inducibility of xenobiotic metabolism in long-term cultures of adult rat liver cell aggregates

1997 ◽  
Vol 11 (1-2) ◽  
pp. 43-56 ◽  
Author(s):  
P. Ammann ◽  
P. Maier
1985 ◽  
Vol 26 (9) ◽  
pp. 1112-1119
Author(s):  
M Rasmussen ◽  
R Blomhoff ◽  
P Helgerud ◽  
L A Solberg ◽  
T Berg ◽  
...  

1990 ◽  
Vol 189 (1) ◽  
pp. 87-92 ◽  
Author(s):  
Jian Zhong Tong ◽  
Olivier Bernard ◽  
Fernando Alvarez

1961 ◽  
Vol 10 (1) ◽  
pp. 95-104 ◽  
Author(s):  
T. S. Leeson ◽  
H. Kalant

A method of in situ perfusion of rat liver via the portal vein is described, by which osmiumtetroxide fixative can be introduced rapidly and uniformly to all parts of the tissue. Previous perfusion with balanced physiological saline solution, under the conditions described, of itself causes minimal change in the liver cell and liver architecture. Perfusion with a chelating agent causes no further detectable alteration within the liver cell but results in separation of the cells, even to the extent of producing a free cell suspension. The separation of cells is not accompanied by any recognizable damage to the plasma membrane but there is a striking tendency to pseudopod formation on the newly exposed surface. These findings provide direct evidence to support the classical concept of the importance of calcium to the adhesiveness of the plasma membrane in the tissues of the adult rat.


2019 ◽  
Vol 4 (1) ◽  
pp. 21-37
Author(s):  
Junichi Kino ◽  
Norihisa Ichinohe ◽  
Masayuki Ishii ◽  
Hiromu Suzuki ◽  
Toru Mizuguchi ◽  
...  

Nature ◽  
1977 ◽  
Vol 267 (5606) ◽  
pp. 58-61 ◽  
Author(s):  
H. L. LEFFERT ◽  
T. MORAN ◽  
R. BOORSTEIN ◽  
K. S. KOCH

2011 ◽  
Vol 112 (5) ◽  
pp. 485-490 ◽  
Author(s):  
Kevin Montagne ◽  
Hongyun Huang ◽  
Keikou Ohara ◽  
Kunio Matsumoto ◽  
Atsushi Mizuno ◽  
...  

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