Poster #S224 CORTISOL LEVELS IN EARLY PSYCHOSIS: SYSTEMATIC REVIEW AND META-ANALYSIS

2014 ◽  
Vol 153 ◽  
pp. S170-S171
Author(s):  
Boris Chaumette ◽  
Oussama Kebir ◽  
Thérèse Jay ◽  
Marie-Odile Krebs
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Cortisol Levels

scholarly journals Pain and Cortisol in Patients with Fibromyalgia: Systematic Review and Meta-Analysis

Diagnostics ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 922
Author(s):  
Edurne Úbeda-D’Ocasar ◽  
Victor Jiménez Díaz-Benito ◽  
Gracia María Gallego-Sendarrubias ◽  
Juan Antonio Valera-Calero ◽  
Ángel Vicario-Merino ◽  
...  
Keyword(s):  
Systematic Review ◽  
Methodological Quality ◽  
Meta Analysis ◽  
Chronic Widespread Pain ◽  
Pain Tolerance ◽  
Therapeutic Interventions ◽  
Widespread Pain ◽  
Cortisol Reactivity ◽  
Pressure Pain Thresholds ◽  
Cortisol Levels

This systematic review and meta-analysis sought to gain further insight into the relationship between cortisol reactivity and chronic widespread pain in patients with fibromyalgia. The studies selected were those conducted in adults with fibromyalgia that were random controlled, non-controlled or observational. Studies were excluded if they examined diseases other than fibromyalgia or if they did not report on pain or cortisol. Twelve studies met inclusion criteria. Data were extracted into tabular format using predefined data fields by two reviewers and assessed for accuracy by a third reviewer. The methodological quality of the studies was assessed using the PEDro scale. Data Synthesis: Of 263 studies identified, 12 were selected for our review and 10 were finally included as their methodological quality was good. In the meta-analysis, we calculated effect sizes of interventions on pain indicators and cortisol levels in patients with fibromyalgia. A small overall effect of all the interventions was observed on pain tolerance and pressure pain thresholds, yet this effect lacked significance (ES = 0.150; 95%CI 0.932–1.550; p > 0.05). Conclusions: While some effects of individual nonpharmacological therapeutic interventions were observed on both cortisol levels and measures of pain, our results suggest much further work is needed to elucidate the true relationship between chronic widespread pain and cortisol levels in patients with fibromyalgia.

scholarly journals A characterization of cortisol level and adrenal reservation in human cardiopulmonary arrest: systematic review and meta-analysis

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Adeleh Sahebnasagh ◽  
Paria Soltani Nejad ◽  
Amin Salehi-Abargouei ◽  
Mohammad Hossein Dehghani ◽  
Fatemeh Saghafi
Keyword(s):  
Systematic Review ◽  
Cortisol Level ◽  
Cardiopulmonary Arrest ◽  
Meta Analysis ◽  
Serum Cortisol ◽  
Large Sample Size ◽  
Baseline Serum ◽  
Significance Level ◽  
Randomized Controlled Studies ◽  
Cortisol Levels

Abstract Background Cardiopulmonary arrest (CPA) is an urgency, which is associated with high mortality. This systematic review evaluated the relationship between baseline cortisol level and the outcome of resuscitated CPA patients. Methods We searched the following databases: PubMed, Scopus, ISI Web of Science, and Google Scholar. Relevant observational and controlled trials were explored from inception by April 2020. The quality of the articles was assessed using the Newcastle-Ottawa Scale (NOS). Results Finally, five cohort studies (n = 201 participants in total) were eligible for including in the meta-analysis. The results of this meta-analysis showed that although the baseline serum cortisol levels were higher in survivors of cardiac arrest compared with non-survivors, the differences between groups do not reach a significance level (Hedges’ g = 0.371, 95% CI, −0.727, 1.469, P value = 0.508). Between-study heterogeneity was statistically significant (Cochrane Q test: P value < 0.001, I2 = 89.323). Conclusions The result of the present meta-analysis was suggestive of a higher baseline serum cortisol levels in survivors of CPA. Future randomized controlled studies with a large sample size will determine the exact relationship between adrenal reservation and the eventual outcome of patients with CPA. Systematic review registration PROSPERO CRD42018085468

Basal cortisol levels and metabolic syndrome: A systematic review and meta-analysis of observational studies

2018 ◽  
Vol 95 ◽  
pp. 50-62 ◽  
Author(s):  
Anderson Garcez ◽  
Heloísa Marquardt Leite ◽  
Elisabete Weiderpass ◽  
Vera Maria Vieira Paniz ◽  
Guilherme Watte ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Observational Studies ◽  
Meta Analysis ◽  
Basal Cortisol ◽  
Cortisol Levels

scholarly journals Effects of parenting interventions on child and caregiver cortisol levels: systematic review and meta-analysis

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Rafaela Costa Martins ◽  
Cauane Blumenberg ◽  
Luciana Tovo-Rodrigues ◽  
Andrea Gonzalez ◽  
Joseph Murray
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Parenting Interventions ◽  
Cortisol Levels

The role of peripheral cortisol levels in suicide behavior: A systematic review and meta-analysis of 30 studies

2020 ◽  
Vol 293 ◽  
pp. 113448
Author(s):  
Yazmin Hernández-Díaz ◽  
Thelma Beatriz González-Castro ◽  
Carlos Alfonso Tovilla-Zárate ◽  
Isela Esther Juárez-Rojop ◽  
María Lilia López-Narváez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Suicide Behavior ◽  
Cortisol Levels

scholarly journals Cognitive Predictors of Social and Occupational Functioning in Early Psychosis: A Systematic Review and Meta-analysis of Cross-Sectional and Longitudinal Data

2021 ◽  
Author(s):  
Megan Cowman ◽  
Laurena Holleran ◽  
Edgar Lonergan ◽  
Karen O’Connor ◽  
Max Birchwood ◽  
...  
Keyword(s):  
Systematic Review ◽  
Social Cognition ◽  
Cognitive Performance ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Medium Effect ◽  
Cross Sectional ◽  
Psychosocial Function ◽  
Cognitive Domains ◽  
Cognitive Predictors

Abstract Many individuals with early psychosis experience impairments in social and occupational function. Identification of modifiable predictors of function such as cognitive performance has the potential to inform effective treatments. Our aim was to estimate the strength of the relationship between psychosocial function in early psychosis and different domains of cognitive and social cognitive performance. We conducted a systematic review and meta-analysis of peer-reviewed, cross-sectional, and longitudinal studies examining cognitive predictors of psychosocial function. Literature searches were conducted in PsycINFO, PubMed, and reference lists of relevant articles to identify studies for inclusion. Of the 2565 identified, 46 studies comprising 3767 participants met inclusion criteria. Separate meta-analyses were conducted for 9 cognitive domains. Pearson correlation values between cognitive variables and function were extracted. All cognitive domains were related to psychosocial function both cross-sectionally and longitudinally. Importantly, these associations remained significant even after the effects of symptom severity, duration of untreated psychosis, and length of illness were accounted for. Overall, general cognitive ability and social cognition were most strongly associated with both concurrent and long-term function. Associations demonstrated medium effect sizes. These findings suggest that treatments targeting cognitive deficits, in particular those focusing on social cognition, are likely to be important for improving functional outcomes in early psychosis.

scholarly journals Cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD): evidence from a systematic review with meta-analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jane Pei-Chen Chang ◽  
Kuan-Pin Su ◽  
Valeria Mondelli ◽  
Carmine M. Pariante
Keyword(s):  
Systematic Review ◽  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Meta Analysis ◽  
Blood Levels ◽  
Inflammatory Biomarker ◽  
Hyperactivity Disorder ◽  
Tnf Α ◽  
Cortisol Levels ◽  
Youth With Adhd

AbstractSeveral studies reported abnormal cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD), but the results have not been conclusive. We conducted a systematic review followed by a meta-analysis of case-control studies assessing blood or saliva cortisol levels and blood levels of inflammatory biomarkers in youth with ADHD. The effect sizes (ES) were synthesized by using a random-effects model. In the 19 studies on cortisol levels (totaling n = 916 youth with ADHD and n = 947 typically developing (TD), healthy youth), youth with ADHD have lower basal cortisol levels at any time-points during the day (effect size: .68; p = 0.004) and lower cumulative levels of cortisol (ES: .39, p = .008) throughout the day than TD youth. Moreover, morning cortisol levels were lower in ADHD youth when compared with TD youth (14 studies, n = 1679, ES: .84, p = 0.003), while there is no difference for the afternoon cortisol levels (p = 0.48). The meta-analysis on inflammation biomarker was conducted on 4 studies (totaling n = 404 youth) showed that Tumour Necrosis Factor-alpha (TNF-α) was lower in ADHD when compared with TD (3 studies, n = 257 youth, p = 0.004), while no differences for Interleukin-1β(IL-1β) (p = 0.21), IL-6 (p = 0.09) and IL-10 (p = 0.77). The lower cortisol in the context of low TNF-α levels may indicate a specific pattern of biomarkers in ADHD, and further investigation is warranted.

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