scholarly journals Do Family Interventions Improve Outcomes in Early Psychosis? A Systematic Review and Meta-Analysis

2017 ◽  
Vol 8 ◽  
Author(s):  
Melanie Claxton ◽  
Juliana Onwumere ◽  
Miriam Fornells-Ambrojo
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Family Interventions

scholarly journals Cognitive Predictors of Social and Occupational Functioning in Early Psychosis: A Systematic Review and Meta-analysis of Cross-Sectional and Longitudinal Data

2021 ◽  
Author(s):  
Megan Cowman ◽  
Laurena Holleran ◽  
Edgar Lonergan ◽  
Karen O’Connor ◽  
Max Birchwood ◽  
...  
Keyword(s):  
Systematic Review ◽  
Social Cognition ◽  
Cognitive Performance ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Medium Effect ◽  
Cross Sectional ◽  
Psychosocial Function ◽  
Cognitive Domains ◽  
Cognitive Predictors

Abstract Many individuals with early psychosis experience impairments in social and occupational function. Identification of modifiable predictors of function such as cognitive performance has the potential to inform effective treatments. Our aim was to estimate the strength of the relationship between psychosocial function in early psychosis and different domains of cognitive and social cognitive performance. We conducted a systematic review and meta-analysis of peer-reviewed, cross-sectional, and longitudinal studies examining cognitive predictors of psychosocial function. Literature searches were conducted in PsycINFO, PubMed, and reference lists of relevant articles to identify studies for inclusion. Of the 2565 identified, 46 studies comprising 3767 participants met inclusion criteria. Separate meta-analyses were conducted for 9 cognitive domains. Pearson correlation values between cognitive variables and function were extracted. All cognitive domains were related to psychosocial function both cross-sectionally and longitudinally. Importantly, these associations remained significant even after the effects of symptom severity, duration of untreated psychosis, and length of illness were accounted for. Overall, general cognitive ability and social cognition were most strongly associated with both concurrent and long-term function. Associations demonstrated medium effect sizes. These findings suggest that treatments targeting cognitive deficits, in particular those focusing on social cognition, are likely to be important for improving functional outcomes in early psychosis.

scholarly journals Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review

2014 ◽  
Vol 24 (5) ◽  
pp. 446-457 ◽  
Author(s):  
G. R. Bond ◽  
R. E. Drake ◽  
A. Luciano
Keyword(s):  
Systematic Review ◽  
Early Intervention ◽  
Educational Outcomes ◽  
Supported Employment ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Empirical Literature ◽  
Employment Rate ◽  
Education Outcomes ◽  
Vocational Services

Aims.Young adults with early psychosis want to pursue normal roles – education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes.Methods.We conducted a systematic review of employment/education outcomes for early intervention programmes, distinguishing three programme types: (1) those providing supported employment, (2) those providing unspecified vocational services and (3) those without vocational services. We summarised findings for 28 studies.Results.Eleven studies evaluated early intervention programmes providing supported employment. In eight studies that reported employment outcomes separately from education outcomes, the employment rate during follow-up for supported employment patients was 49%, compared with 29% for patients receiving usual services. The two groups did not differ on enrolment in education. In four controlled studies, meta-analysis showed that the employment rate for supported employment participants was significantly higher than for control participants, odds ratio = 3.66 [1.93–6.93],p < 0.0001. Five studies (four descriptive and one quasi-experimental) of early intervention programmes evaluating unspecified vocational services were inconclusive. Twelve studies of early intervention programmes without vocational services were methodologically heterogeneous, using diverse methods for evaluating vocational/educational outcomes and precluding a satisfactory meta-analytic synthesis. Among studies with comparison groups, 7 of 11 (64%) reported significant vocational/education outcomes favouring early intervention over usual services.Conclusions.In early intervention programmes, supported employment moderately increases employment rates but not rates of enrolment in education. These improvements are in addition to the modest effects early programmes alone have on vocational/educational outcomes compared with usual services.

Aripiprazole in young people with early psychosis: a systematic review and meta-analysis of weight gain

2022 ◽  
pp. 103985622110373
Author(s):  
Arti Parmar ◽  
Donald Hulme ◽  
Daniel Hacking ◽  
Gordon Shymko ◽  
Milan Dragovic ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Gain ◽  
Young People ◽  
Effect Size ◽  
Weight Change ◽  
Patient Monitoring ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Inclusion Criteria ◽  
Early Implementation

Objective: Aripiprazole is often prescribed to young people, although there remain unanswered questions about its effects on weight gain. This study undertook a meta-analysis of weight gain occurring in young people with early psychosis who were prescribed aripiprazole. Method: A systematic search was conducted for studies reporting on aripiprazole and weight change in young people with a psychotic disorder. A meta-analysis integrated the data into an estimate of effect size. Results: Eleven studies met the inclusion criteria amounting to 886 participants (mean age 18 years). The results showed significant weight gain averaging 2.7 kg. These increases were associated with a longer duration of exposure to aripiprazole but not a higher dosage. Conclusions: The results highlight the importance of regular patient monitoring and the early implementation of interventions to manage antipsychotic-related weight gain.

Poster #S224 CORTISOL LEVELS IN EARLY PSYCHOSIS: SYSTEMATIC REVIEW AND META-ANALYSIS

2014 ◽  
Vol 153 ◽  
pp. S170-S171
Author(s):  
Boris Chaumette ◽  
Oussama Kebir ◽  
Thérèse Jay ◽  
Marie-Odile Krebs
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Early Psychosis ◽  
Cortisol Levels

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

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