This article presents a clinical case demonsratinga high metastatic potential of clear cell renal cell carcinoma combined with atypical metastases to breast and paranasal sinuses. The prevalence of metastatic lesions to the breast and paranasal sinuses in various malignant tumors depending on their morphological forms is analyzed. The authors present an analysis of data published for the last 30 years. The optimal diagnostic algorithms to detect the progression of renal cell carcinoma and to evaluate the effectiveness of the treatment are considered.
Tissue Microarray (TMA) and VHL Mutations as Predictors of Outcome in Advanced Clear Cell Renal Cell Carcinoma (CCRCC) Treated with Firs Line Sunitinib