P-187 - Bipolar affective disorder and dissociation - comparison with healthy controls

IntroductionAccording to recent findings, certain clinical symptoms of the patients suffering from affective and anxiety disorder can be related to dissociation. The aim of our study is to examine if the level of dissociation in bipolar affective disorder differ from the level of dissociation in healthy volunteers.Methods41 patients suffering from bipolar disorder (51.2% females), and 198 healthy controls (71.2% females) were included in the study. The patients with bipolar affective disorder in remission of the illness were recruited from the Outpatient psychiatric department of Psychiatry Clinic of University hospital Olomouc. Patients were psychiatrically assessed and the state of the disorder was evaluated by experienced psychiatrist. Only patients in remission of the disorder, evaluated as 1 or 2 points of clinical global impression - severity scale, were included into the study. All participants were assessed with the Dissociative Experiences Scale (DES).ResultsThe groups didn’t differ in demographic variables like age, gender and education. Patients had significantly higher mean score on the DES and pathological DES than healthy controls.ConclusionOur results suggest that the level of psychological dissociation in bipolar affective patients is higher than in healthy controls.Supported by grant IGA MZ ČR NT11047

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BIPOLAR AFFECTIVE DISORDER AND DISSOCIATION - COMPARISON WITH HEALTHY CONTROLS

Biomedical Papers ◽

10.5507/bp.2011.007 ◽

2011 ◽

Vol 155 (2) ◽

pp. 181-186 ◽

Cited By ~ 10

Author(s):

Klara Latalova ◽

Jan Prasko ◽

Petr Pastucha ◽

Ales Grambal ◽

Dana Kamaradova ◽

...

Keyword(s):

Affective Disorder ◽

Bipolar Affective Disorder ◽

Healthy Controls

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Use of Dermatoglyphic Parameters as Possible Markers in Bipolar Affective Disorder

International Journal of Health Sciences and Research ◽

10.52403/ijhsr.20210753 ◽

2021 ◽

Vol 11 (7) ◽

pp. 385-393

Author(s):

Amit Kumar Pal ◽

Sagarika Ray ◽

Jishnu Bhattacharya

Keyword(s):

Bipolar Disorder ◽

Affective Disorder ◽

Bipolar Affective Disorder ◽

Control Group ◽

Healthy Controls ◽

Ridge Count ◽

Primordial Prevention ◽

And Gender ◽

The Individual ◽

Bipolar Patients

Background: Bipolar affective disorder is an episodic illness characterized by fluctuating mood states. Association of dermatoglyphic traits with bipolar affective disorder has been observed in various studies. This study was undertaken to evaluate epidermal ridge patterns in bipolar patients as compared to healthy controls attending a super speciality district hospital in West Bengal. Context and purpose of study: Establishing dermatoglyphic parameters as biomarkers for early diagnosis and consequently, prompt intervention in bipolar affective disorder will ensure a greater scope of recovery, and thus promote a better quality of life for the individual as well as lower the burden of disease for the society. Methods: Quantitative dermatoglyphic parameters namely, Total Finger Ridge Count (TFRC), Total A-B Ridge Count (TABRC), and ATD Angle of 100 bipolar patients were compared to 100 age and gender matched healthy controls. Results: Statistically significant differences were found on comparing the dermatoglyphic parameters between cases and controls. TFRC was found to be decreased while ATD angle was increased in bipolar cases, as compared to the control group. However, no significant change was observed in TABRC between the two groups. Conclusions: This study found a significant association between dermatoglyphic pattern anomalies and the development of bipolarity. This may offer a scope of primordial prevention of bipolar disorder in future. Key words: Dermatoglyphics, ridge pattern, bipolar disorder, Total Finger Ridge Count (TFRC), Total A-B Ridge Count (TABRC), ATD angle.

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Antinuclear autoantibodies in relation to bipolar affective disorder and lithium therapy

European Psychiatry ◽

10.1016/0924-9338(96)80459-7 ◽

1996 ◽

Vol 11 (1) ◽

pp. 50-52 ◽

Cited By ~ 6

Author(s):

B Spivak ◽

M Radwan ◽

P Bartur ◽

R Mester ◽

A Weizman

Keyword(s):

Affective Disorder ◽

Antinuclear Antibodies ◽

Lithium Treatment ◽

Bipolar Affective Disorder ◽

Lithium Therapy ◽

Healthy Controls ◽

Antinuclear Autoantibodies ◽

Dna Antibodies ◽

Bipolar Patients ◽

Drug Free

SummaryWe investigated the presence of antinuclear antibodies (ANA) in 63 drug free and lithium treated bipolar patients as compared to 37 healthy controls. Increased frequency of positive ANA was detected in bipolar patients in comparison to controls (19% vs 5%, respectively, P < 0.05). This finding was unrelated to lithium treatment. No antinative DNA antibodies or antihistone reactive antibodies were detected among the ANA positive subjects.

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