Typical and atypical antipsychotics in the treatment of mania

2001 ◽  
Vol 11 ◽  
pp. S132
Author(s):  
G.M. Goodwin
2010 ◽  
Vol 22 (3) ◽  
pp. 501-502 ◽  
Author(s):  
Fozia Roked ◽  
Asha Omar ◽  
Fayaz Roked ◽  
Ridwan Ahmed ◽  
Abdul Patel

In 2007, the U.K.'s All-Party Parliamentary Group on Dementia (APPG) undertook an inquiry into the prescription of antipsychotics for people with dementia on account of concerns expressed by carers, patient organizations and academics about the appropriateness and safety of these drugs (All-Party Parliamentary Group on Dementia, 2008). It has been estimated that 32% of patients with dementia in care homes are prescribed antipsychotics (Alldred et al., 2007). Both typical and atypical antipsychotics are associated with QT prolongation, which can lead to arrhythmias and sudden death (Joint Formulary Committee, 2009). They are also associated with an increased risk of cerebrovascular events. Adverse effects in the elderly include excessive sedation and dizziness, which can lead to falls and therefore accelerated cognitive decline.


Author(s):  
Kelly Juliana Seibt ◽  
Renata da Luz Oliveira ◽  
Eduardo Pacheco Rico ◽  
Renato Dutra Dias ◽  
Mauricio Reis Bogo ◽  
...  

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