Long-term tillage effects on changes in structural properties of two soils in central Ohio1Contribution from The School of Natural Resources, The Ohio State University, Columbus, OH, USA.1

1998 ◽  
Vol 45 (1-2) ◽  
pp. 107-118 ◽  
Author(s):  
A.A Mahboubi ◽  
R Lal
Keyword(s):  
Natural Resources ◽  
Structural Properties ◽  
Ohio State University ◽  
State University ◽  
The Ohio State University

scholarly journals Using Metabolomics to Classify the Underlying Effects of Multi-Nutrient Supplementation in ADHD Youth

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1351-1351
Author(s):  
Madeline Stern ◽  
Leanna Perez ◽  
Jeanette Johnstone ◽  
Barbara Gracious ◽  
Brenda Leung ◽  
...  
Keyword(s):  
Medical Center ◽  
Ohio State University ◽  
State University ◽  
Adhd Symptoms ◽  
Open Label ◽  
Nutrient Supplementation ◽  
Open Label Phase ◽  
The Ohio State University ◽  
Double Blinded

Abstract Objectives Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder commonly diagnosed in childhood. Current pharmaceutical treatment options provide a poor long-term risk: benefit ratio with little knowledge of the long-term effects. A broad-spectrum multi-nutrient formula has shown promise in children, but its effects on nutrient status and the underlying metabolome interactions have not been characterized. Methods Blood samples from medication-free children (n = 74) with ADHD enrolled in a double–blind randomized placebo-controlled multinutrient trial (RCT) were collected at baseline and 8 weeks post-intervention. Following RCT is an 8-week open label phase during which all participants took the active supplement. Symptoms were assessed using the Child and Adolescent Symptom Inventory 5. Double-blinded plasma samples will be analyzed for tyrosine, phenylalanine, tryptophan, magnesium, and zinc. Untargeted LC-MS metabolomics using HILIC chromatography and a high resolution QTof will assess very polar analytes in plasma extracts. Linear modeling will elucidate the influence of treatment, sampling time, and ADHD symptom score on plasma nutrient and plasma metabolite concentration. Results Preliminary findings of the open label phase show a significant improvement in inattention (P = 0.0435), hyperactivity (P = 0.0068), ODD (P = 0.0108) and DMDD (P = 0.0119). We hypothesize that these improvements in ADHD symptoms will be correlated with increased circulating concentrations of tyrosine, phenylalanine, tryptophan, magnesium, zinc, and metabolites involved in neurotransmitter synthesis and/or branched chain amino acid metabolism. Conclusions Preliminary findings indicate improvements of ADHD symptoms of inattention, hyperactivity, ODD and DMDD following 8 weeks of open label multi-nutrient supplementation. Results of the double-blinded phase are expected to mirror those observed in the open label phase, with increases in nutrients in those receiving the multinutrient. Funding Sources The sample analyses were supported by NIH Award Number Grant P30 CA016058, OSU, and OSUCCC. Foundation for the Center of Excellence in Mental Health, Canada; The Ohio State University Department of Human Sciences, College of Education and Human Ecology; The Ohio State University Wexner Medical Center, Clinical Research Center.

scholarly journals The Engineered Course of Treatment

2001 ◽  
Vol 123 (12) ◽  
pp. 44-47 ◽  
Author(s):  
Mauro Ferrari ◽  
Jun Liu
Keyword(s):  
Three Dimensional ◽  
Coronary Bypass ◽  
Therapeutic Agents ◽  
Ohio State University ◽  
State University ◽  
Valve Repair ◽  
Surgical Field ◽  
Computer Controlled ◽  
The Ohio State University

Use of nanoscale devices is helping to revolutionize medical treatment and research. The Ohio State University recently became the first place in the country where coronary bypass and mitral valve repair operations are performed by a computer controlled robot, operated by a remotely located surgeon handling joysticks and considering a three-dimensional, enlarged view of the surgical field. With the invaluable help of many associates and students, researchers have focused on two classes of objects: devices that feature nanopore membranes, and multifunctional particulates for the delivery of medical therapeutic agents. Nanomembranes may also be used as flux regulators for the long-term release of biopharmaceuticals from implanted depots. This application embodies a purely passive mass transport mode of molecules in channels that are just a few nanometers larger than the effective radii of the molecules themselves.

scholarly journals Cardiovascular Disease is a Leading Cause of Mortality among TTP Survivors in Clinical Remission

2021 ◽  
Author(s):  
Senthil Sukumar ◽  
Max Alexander Brodsky ◽  
Sarah Hussain ◽  
Lisa R Yanek ◽  
Alison R. Moliterno ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cause Of Death ◽  
Reference Population ◽  
Ohio State University ◽  
State University ◽  
Risk Of Death ◽  
Long Term Follow Up ◽  
The Ohio State University

iTTP survivors experience high rates of adverse health sequelae and increased mortality over long-term follow up. We conducted this multi-center cohort study to evaluate long-term mortality and causes of death in iTTP survivors. Between 2003 and 2020, 222 patients were enrolled in the Ohio State University and Johns Hopkins TTP registries and followed for a median of 4.5 (interquartile range [IQR],75 0.4-11.5) years. Nine patients died during their first iTTP episode and 29 patients died during follow-up. Mortality rate was 1.8 times higher than expected from an age, sex and race adjusted reference population. Cardiovascular disease was a leading primary cause of death (27.6%) tied with relapsed iTTP (27.6%), followed by malignancy (20.7%), infection (13.8%), and other causes (10.3%). Male sex [HR 3.74 (95% CI 1.65-8.48, P=0.002), increasing age [HR 1.04 (95% CI 1.01-1.07), P=0.011] and number of iTTP episodes [HR 1.10 (95% CI 1.01-1.20), P=0.022] were associated with mortality in a model adjusted for African American race [HR 0.70 (95% CI 0.30-1.65), P=0.702], hypertension [HR 0.47 (95% CI 0.20-1.08), P=0.076], CKD [HR 1.46 (95% CI 0.65-3.30, P=0.358] and site [HR 1.46 (95% CI 0.64-3.30), P=0.358]. There was a trend towards shorter survival in patients with lower ADAMTS13 activity during remission (P=0.078). In conclusion, iTTP survivors are at higher risk of death compared with a reference population and cardiovascular disease is a leading cause of death. Our study highlights the need for survivorship care, and investigation focused on cardiovascular disease and early mortality in TTP survivors.

scholarly journals A Radio Frequency Interference Survey of Central Ohio

1991 ◽  
Vol 112 ◽  
pp. 181-187
Author(s):  
Robert S. Dixon ◽  
Steven W. Ellingson ◽  
Ronald J. Koch
Keyword(s):  
Radio Frequency ◽  
Monitoring Program ◽  
Ohio State University ◽  
Radio Frequency Interference ◽  
State University ◽  
Directional Information ◽  
Radio Observatory ◽  
The Ohio State University ◽  
Airline Schedules

ABSTRACTA long-term radio frequency interference monitoring program is now in progress at the Ohio State University Radio Observatory. Current observations encompass the 1-2 GHz band, measuring the signal strength in each 150 KHz subband. Preliminary results show many strong and persistent signals, and wide bands in which no signals are detected. Daily and weekly variations appear to be correlated with periods of maximum human activity such as “rush hours”. It may be that aircraft reflections are causing many of the signals to be received, and that airline schedules correlate with “rush hours”. The program is being upgraded to automatically measure the direction of arrival of each signal, as an aid to further identify it. This directional information will also be used in designing rolled edges and side shields for the co-located OSU Radio Telescope, to further reduce its vulnerability to RFI.

scholarly journals OSUL2013: Fostering Organizational Change through a Grassroots Planning Process

2011 ◽  
Vol 72 (2) ◽  
pp. 152-165 ◽  
Author(s):  
Melanie Schlosser
Keyword(s):  
Organizational Change ◽  
Planning Process ◽  
Ohio State University ◽  
State University ◽  
University Libraries ◽  
Third Phase ◽  
Organizational Culture Change ◽  
The Ohio State University ◽  
Innovative Culture

This paper provides background on planning and organizational culture change in libraries and describes a grassroots planning process taking place at the Ohio State University Libraries. Now in its third phase, the process aims to create a long-term plan for the organization while fostering a more collaborative, innovative culture.

Five Decades of Research Experience in Speech Anatomy and Physiology

2016 ◽  
Vol 1 (5) ◽  
pp. 4-12
Author(s):  
David P. Kuehn
Keyword(s):  
Ohio State University ◽  
State University ◽  
Research Experience ◽  
University Of Iowa ◽  
University Of Illinois ◽  
Anatomy And Physiology ◽  
The Ohio State University ◽  
Speech Science ◽  
The University ◽  
East Carolina University

This report highlights some of the major developments in the area of speech anatomy and physiology drawing from the author's own research experience during his years at the University of Iowa and the University of Illinois. He has benefited greatly from mentors including Professors James Curtis, Kenneth Moll, and Hughlett Morris at the University of Iowa and Professor Paul Lauterbur at the University of Illinois. Many colleagues have contributed to the author's work, especially Professors Jerald Moon at the University of Iowa, Bradley Sutton at the University of Illinois, Jamie Perry at East Carolina University, and Youkyung Bae at the Ohio State University. The strength of these researchers and their students bodes well for future advances in knowledge in this important area of speech science.

Cardiology Fellowship Education in the Era of High-density Training, Data Tracking, and Quality Measures

2011 ◽  
Vol 9 (2) ◽  
pp. 99
Author(s):  
Alex J Auseon ◽  
Albert J Kolibash ◽  
◽  
Keyword(s):  
Ohio State University ◽  
Training Data ◽  
State University ◽  
Training Requirements ◽  
Healthcare Environment ◽  
Medical Centers ◽  
Work Hour ◽  
The Ohio State University ◽  
Data Tracking

Background:Educating trainees during cardiology fellowship is a process in constant evolution, with program directors regularly adapting to increasing demands and regulations as they strive to prepare graduates for practice in today’s healthcare environment.Methods and Results:In a 10-year follow-up to a previous manuscript regarding fellowship education, we reviewed the literature regarding the most topical issues facing training programs in 2010, describing our approach at The Ohio State University.Conclusion:In the midst of challenges posed by the increasing complexity of training requirements and documentation, work hour restrictions, and the new definitions of quality and safety, we propose methods of curricula revision and collaboration that may serve as an example to other medical centers.

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