Ultrasonic evaluation of the relationship between left ventricular hypertrophy or left ventricular geometry and endothelial function in patients with essential hypertension

2009 ◽  
Vol 23 (6) ◽  
pp. 415-419
Author(s):  
Jing Dong ◽  
Pingyang Zhang ◽  
Xuehong Feng ◽  
Chong Wang ◽  
Pei Wang
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Endothelial Function ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry ◽  
Ultrasonic Evaluation ◽  
The Relationship

scholarly journals Lipid profile and left ventricular geometry pattern in obese children

2020 ◽  
Author(s):  
Bojko Bjelakovic ◽  
Claudia Stefanutti ◽  
Vladimir Vukovic ◽  
Nebojsa Kavaric ◽  
Ljiljana Saranac ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Serum Lipid ◽  
Ventricular Hypertrophy ◽  
Density Lipoprotein ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Obese Children ◽  
Ventricular Geometry ◽  
The Relationship ◽  
Age And Sex

Abstract Background: Left ventricular hypertrophy (LVH) is an important risk factor for cardiovascular and all-cause mortality. Previous studies reported conflicting results concerning the relationship between serum lipid levels and left ventricular geometry pattern. We sought to explore the relationship between standard serum lipid profile measures with left ventricular geometry pattern in obese children. Patients and methods : In this cross-sectional study, a total of 70 obese children were examined. Fasting blood samples were taken to measure total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TGs), glucose, and insulin. Based on these values TG / HDL ratio, BMI and HOMA index were calculated. We also measured the average 24-hour ambulatory systolic blood pressure (SBP) and two-dimensional (2/D) transthoracic echocardiography was performed to determine left ventricular mass index (LVMI) and relative wall thickness (RWT). Multiple regression analyses with stepwise selection were conducted to explore relationships between study variables and the LVMI or RWT as outcome variables. The final model with LVMI included TG/HDL ratio, BMI, 24h-average SBP, age and sex, while for the RWT we included BMI, insulin, age and sex. Results : Our study included 70 children (65.71% boys and 34.29% girls) with median age (14 years, IQR=12-16)." We demonstrated independent and positive association of TG/HDL ratio, BMI and 24h-average SBP with LVMI (effect=3.65, SE=1.32, p<0.01; effect=34.90, SE=6.84, p<0.01; effect=0.32, SE=0.12, p<0.01, respectively). On the other hand, in model with RWT as outcome variable, only BMI and insulin were significantly linked (BMI: effect=13.07, SE=5.02, p=0.01 Insulin: effect=2.80, SE=0.97). Conclusion: Increased TG/HDL ratio in obese children is associated with the development of eccentric left ventricular hypertrophy while increased BMI and insulin were associated with concentric left ventricular hypertophy.

scholarly journals Left ventricular hypertrophy and outcomes: A five-year retrospective analysis of patients with essential hypertension

2012 ◽  
Vol 18 (5) ◽  
pp. 385-397 ◽  
Author(s):  
A. V. Barsukov ◽  
M. P. Zobnina ◽  
M. S. Talantseva
Keyword(s):  
Essential Hypertension ◽  
Left Ventricular Hypertrophy ◽  
Retrospective Analysis ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry ◽  
Cardiovascular Prognosis ◽  
Cardiovascular Continuum ◽  
Overall Mortality

Left ventricular hypertrophy (LVH) is the most important element of cardiovascular continuum in patients with essential hypertension (EH). The results of a five-year retrospective analysis of EH patients cohort with initially different types of left ventricular geometry (491 subjects) are presented. It is shown that the overall mortality in patients with concentric and eccentric LVH does not differ significantly (37 and 35 %, respectively) but exceeds that in subjects with normal LV geometry (20 %). Associated and concomitant pathology determine the total and cardiovascular prognosis more in patients with concentric LVH than in subjects with eccentric LVH. The presence of ECG valid quantitative and strain diagnostic LVH criteria (Sokolow-Lyon index and Perugian university sign) determines the worst remote prognosis in patients with both concentric and eccentric LVH. The enlarged size of the left atrium is an universal marker of poor outcome in hypertensive patients regardless the type оf left ventricular geometry.

scholarly journals Lipid profile and left ventricular geometry pattern in obese children

2020 ◽  
Author(s):  
Bojko Bjelakovic ◽  
Claudia Stefanutti ◽  
Vladimir Vukovic ◽  
Nebojsa Kavaric ◽  
Ljiljana Saranac ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Serum Lipid ◽  
Ventricular Hypertrophy ◽  
Density Lipoprotein ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Obese Children ◽  
Ventricular Geometry ◽  
The Relationship ◽  
Age And Sex

Abstract Background: Left ventricular hypertrophy (LVH) is an important risk factor for cardiovascular and all-cause mortality. Previous studies reported conflicting results concerning the relationship between serum lipid levels and left ventricular geometry pattern. We sought to explore the relationship between standard serum lipid profile measures with left ventricular geometry pattern in obese children.Patients and methods: In this cross-sectional study, a total of 70 obese children were examined. Fasting blood samples were taken to measure total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TGs), glucose, and insulin. Based on these values TG/HDL ratio, BMI and HOMA index were calculated. We also measured the average 24-hour ambulatory systolic blood pressure (SBP) and two-dimensional (2/D) transthoracic echocardiography was performed to determine left ventricular mass index (LVMI) and relative wall thickness (RWT). Multiple regression analyses were conducted to explore relationships between study variables and the LVMI or RWT as outcome variables. The final model with LVMI included TG/HDL ratio, BMI, 24h-average SBP, age and sex, while for the RWT we included BMI, insulin, age and sex.Results: Our study included 70 children (65.71% boys and 34.29% girls) median age (14 years, IQR=12-16)." We demonstrated independent and positive association of TG/HDL ratio, BMI and 24h-average SBP with LVMI (effect=3.65, SE=1.32, p<0.01; effect=34.90, SE=6.84, p<0.01; effect=0.32, SE=0.12, p<0.01, respectively). On the other hand, in model with RWT as outcome variable, only BMI and insulin were significantly linked (BMI: effect=13.07, SE=5.02, p=0.01 Insulin: effect=2.80, SE=0.97).Conclusion: Increased TG/HDL ratio in obese children is associated with the development of eccentric left ventricular hypertrophy while increased BMI and insulin were associated with concentric left ventricular hypertophy.

scholarly journals A 4-Tiered Classification of Left Ventricular Hypertrophy Based on Left Ventricular Geometry

2010 ◽  
Vol 3 (2) ◽  
pp. 164-171 ◽  
Author(s):  
Michel G. Khouri ◽  
Ronald M. Peshock ◽  
Colby R. Ayers ◽  
James A. de Lemos ◽  
Mark H. Drazner
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry

scholarly journals 5-YEAR DYNAMICS OF FEATURES OF LEFT VENTRICULAR GEOMETRY IN PATIENTS WITH ISCHEMIC HEART DISEASE, DEPENDING ON TREATMENT TACTICS

2019 ◽  
Vol 19 (3) ◽  
pp. 17-21
Author(s):  
R.R. Guta ◽  
N.S. Beck ◽  
O.M. Radchenko
Keyword(s):  
Heart Disease ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Comparison Group ◽  
Myocardial Revascularization ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Ventricular Geometry ◽  
Concentric Left Ventricular Hypertrophy ◽  
Eccentric Hypertrophy

Introduction. For a patient with coronary heart disease, recovery from myocardial revascularization is a complex process. Cardiac remodeling involves, after myocardial infarction, hypertrophy and dilation, resulting in impaired systolic-diastolic cardiac function, which is an additional risk factor for events. Prospective studies have shown a relationship between left ventricular size and the risk of cardiovascular events. Given this, there was a need to conduct our research. Purpose: To determine the prevalence of types of left ventricular geometry in patients with coronary heart disease, post-infarction cardiosclerosis, depending on therapeutic tactics: revascularization or conservative therapy for 60 months. Material and Methods: We examined 101 patients aged 58.6±4.2 years after myocardial revascularization (n = 71) and with conservative treatment only (n = 30), in whom the dynamics of echocardiographic parameters of the heart were evaluated for 5 years. The values ​​of remodeling myocardial mass index of the left ventricle and the relative thickness of the left ventricle were determined. Results and Discussion. At baseline, patients with concentric left ventricular hypertrophy (50.0%) and concentric remodeling (24.1%) predominated in the main group. Normal geometry in 14.8% and eccentric left ventricular hypertrophy were observed in 11.1%. In the comparison group, eccentric hypertrophy and concentric left ventricular remodeling were most commonly observed, 29.6% each, slightly less than 25.9% concentric hypertrophy, and the least was normal geometry (14.8%). After 60 months, patients with both groups did not experience normal left ventricular geometry and concentric remodeling. The concentric type (80.0%) was predominant in the main group, and the eccentric type (55.6%) in the comparison group. Conclusions. In patients with ischemic heart disease, postinfarction cardiosclerosis progresses in 5 year follow-up myocardial hypertrophy regardless of treatment. After revascularization, concentric left ventricular hypertrophy develops more often, whereas under conservative treatment, left ventricular eccentric hypertrophy is combined with systolic dysfunction and left atrial dilatation. After revascularization, an increase in the index was associated with an increase not only in body weight but also in changes in lipid profile and diastolic hypertension.

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