scholarly journals Low Maternal Serum Levels of Pregnancy-associated Plasma Protein-A During the First Trimester are Associated with Subsequent Preterm Delivery with Preterm Premature Rupture of Membranes

2007 ◽  
Vol 46 (3) ◽  
pp. 242-247 ◽  
Author(s):  
Bo-Quing She ◽  
Su-Chee Chen ◽  
Fa-Kung Lee ◽  
Mei-Leng Cheong ◽  
Ming-Song Tsai
Keyword(s):  
Preterm Delivery ◽  
Plasma Protein ◽  
Protein A ◽  
Serum Levels ◽  
First Trimester ◽  
Maternal Serum ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture

scholarly journals Successful outcome after spontaneous first trimester intra-amniotic haematoma and early preterm premature rupture of membranes

2018 ◽  
Vol 11 (1) ◽  
pp. e224596
Author(s):  
Spyros Bakalis ◽  
Anna L David
Keyword(s):  
Preterm Delivery ◽  
First Trimester ◽  
Successful Outcome ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Maternal Complications ◽  
Preterm Premature Rupture ◽  
Spontaneous Preterm Delivery ◽  
First Trimester Of Pregnancy

A spontaneous intra-amniotic haematoma is a rare cause of preterm premature rupture of the membranes (PPROM) but can have significant fetal and maternal consequences. It has previously been reported to occur in the second and third trimesters but not in an earlier gestation. We present a case that presented acutely in the first trimester of pregnancy, which leads to early PPROM at 15 weeks and spontaneous preterm delivery at 28 weeks of gestation. There were no maternal complications during the pregnancy.

Usefulness of maternal serum C-reactive protein with vaginal Ureaplasma urealyticum as a marker for prediction of imminent preterm delivery and chorioamnionitis in patients with preterm labor or preterm premature rupture of membranes

2015 ◽  
Vol 43 (4) ◽  
Author(s):  
Dong-Wook Kwak ◽  
Hee-Young Cho ◽  
Ja-Young Kwon ◽  
Yong-Won Park ◽  
Young-Han Kim
Keyword(s):  
Preterm Delivery ◽  
Preterm Labor ◽  
Maternal Serum ◽  
C Reactive Protein ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Reactive Protein ◽  
Preterm Premature Rupture ◽  
Serum Crp ◽  
Genital Mycoplasmas

AbstractTo assess whether maternal serum C-reactive protein (CRP) and genital mycoplasmas measured can help predict imminent preterm delivery or chorioamnionitis in patients with preterm labor (PL) or preterm premature rupture of membranes (PPROM).The study group consisted of 165 women with PL or PPROM. Vaginal cultures for genital mycoplasmas and maternal blood for CRP were obtained when they were admitted for the management of PL or PPROM. An elevated level of serum CRP was defined as ≥0.8 mg/dL. Histologic evaluation of the placenta was performed after delivery.The prevalence of positive vaginal fluid cultures forAlthough vaginal UU in PL or PPROM cannot act as the sole predictor of imminent preterm delivery or chorioamnionitis, it can provide predictive information in patients with elevated maternal serum CRP levels.

Japanese maternal serum levels of Pregnancy Associated Plasma Protein A (PAPP-A) in the first trimester in association with abnormal fetal karyotype

Placenta ◽  
1994 ◽  
Vol 15 (7) ◽  
pp. A92
Author(s):  
Junko Takada ◽  
Seiko Iiduka ◽  
Shizuko Yamabe ◽  
Yosichika Suzuki ◽  
Hitoshi Funayama ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Protein A ◽  
Serum Levels ◽  
First Trimester ◽  
Maternal Serum ◽  
Fetal Karyotype

Correlation of neonatal weight with maternal serum levels of pregnancy-associated plasma protein-A during the first trimester of pregnancy: a retrospective study

2015 ◽  
Vol 43 (2) ◽  
Author(s):  
Ivana Giudice ◽  
Gianfranco Benintende ◽  
Anna Maria Di Nicolò ◽  
Daniela Mangiameli ◽  
Grazia Carrara ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Fetal Growth ◽  
Plasma Protein ◽  
Protein A ◽  
Screening Method ◽  
Serum Levels ◽  
First Trimester ◽  
Maternal Serum ◽  
Perinatal Complications ◽  
First Trimester Of Pregnancy

AbstractEvaluate the relationship between neonatal weight and pregnancy-associated plasma protein-A.Retrospective study on 2564 singleton pregnancies with healthy term neonates in three groups of women with different values of pregnancy-associated plasma protein-A who underwent the combined test during the first trimester. Non-parametric test and correlation analysis for statistical elaboration were carried out.There exists a correlation between the serum levels of pregnancy-associated plasma protein-A in the first trimester of pregnancy and neonatal weight. Values of pregnancy-associated plasma protein-A lower than the 25This study confirms the positive correlation between circulating concentrations of pregnancy-associated plasma protein-A and fetal growth. Low neonatal weight and factors that can cause this could be determined from the first trimester by measuring the concentrations of pregnancy-associated plasma protein-A in maternal serum. Even if the association between the levels of pregnancy-associated plasma protein-A and a low neonatal weight has been demonstrated, however, we have to say that the sensitivity of a such screening method for the prediction of low birth weight and perinatal complications seems to be rather low. The variations of pregnancy-associated plasma protein-A during the first trimester cannot be used as a marker of excessive fetal growth.

scholarly journals Risk Factors for Neonatal Bronchopulmonary Dysplasia in Extremely Preterm Premature Rupture of Membranes: A Retrospective Study

2020 ◽  
Author(s):  
Eishin Nakamura ◽  
Shigetaka Matsunaga ◽  
Yoshihisa Ono ◽  
Yasushi Takai ◽  
Hiroyuki Seki
Keyword(s):  
Risk Factors ◽  
Preterm Delivery ◽  
Bronchopulmonary Dysplasia ◽  
Roc Curve ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Preterm Premature Rupture ◽  
Extremely Preterm ◽  
Gestational Week ◽  
The Mean

Abstract Background: Determination of the optimal timing for termination of pregnancy in cases of preterm premature rupture of membranes (pPROM) during the extremely preterm period is still difficult. Bronchopulmonary dysplasia (BPD) is a major disease widely taken into account when determining the prognosis of respiratory disorders in a neonate. Many aspects of this disease remain unclear. With the aim of further improving the prognosis of neonates born to mothers with pPROM, this study examined cases who were diagnosed with pPROM before 28 weeks of gestation. The study analysed risk factors for neonatal BPD. Methods: This study included 73 subjects with singleton pregnancy, diagnosed with pPROM during the gestational period from 22 weeks and 0 days to 27 weeks and 6 days. The following factors were retrospectively examined: the gestational week at which pPROM was diagnosed, the gestational week at which delivery occurred, the period for which the volume of amniotic fluid was maintained, and neonatal BPD as a complication. Receiver operating characteristic (ROC) curve analyses were conducted to analyse the relationship of the onset of BPD with the duration of oligohydramnios and the gestational weeks of delivery. Results: The mean gestational week at which a diagnosis of amniorrhexis was made was 24.5±1.9 weeks (mean±SD), and that at which delivery occurred was 27.0±3.0 weeks. Fifty-seven cases (78.1%) were diagnosed with oligohydramnios, the mean duration of which was 17.4±20.5 days. The mean birth weight of neonates was 1000±455 g, of which 49 (67.1%) were diagnosed with BPD following birth. No neonates died in this study. The ROC curve indicated that the cut-off values for the duration of oligohydramnios and gestational age at delivery were 4 days and 24.1 weeks, respectively. Multivariate analysis indicated that the duration of oligohydramnios for more than 4 days before delivery and preterm delivery at less than 24.1 weeks were risk factors for the onset of BPD. Conclusion: Our findings suggest that duration of oligohydramnios for more than 4 days before delivery and preterm delivery less than 24.1 weeks are risk factors for BPD in cases who are diagnosed with pPROM before 28 weeks of gestation.

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