P265 DEVELOPMENT AND VALIDATION OF GLYCOSAMINOGLYCAN (“GAG”) DEPLETION MAPPING IN OSTEOARTHRITIS USING DELAYED CONTRAST ENHANCED HIGH RESOLUTION MRI

Purpose To explore the feasibility of high-resolution MRI 3-dimensional (3D) CUBE T1-weighted magnetic resonance imaging (MRI) in combination with non-contrast-enhanced (NCE) magnetic resonance venography (MRV) for the assessment of lumen stenosis in May–Thurner syndrome. Methods Twenty-nine patients underwent computed tomography venography (CTV) and high-resolution MRI-CUBE T1, and NCE MRV acquisitions. ANOVA and LSD tests were used to compare the stenosis rate and narrowest and distal diameters of the vessel lumen. Results There were no significant differences in the estimated stenosis rate between CTV, CUBE T1, and NCE MRV (p = 0.768). However, there were significant differences in the measured stenosis diameters of the left common iliac vein (LCIV), with CTV giving the largest mean diameter and CUBE had the smallest mean diameter (p < 0.05). The measured normal LCIV diameters did not significantly differ between MRV and CUBE (p = 0.075) but were significantly larger on CTV than on MRV and CUBE (p < 0.05). Conclusions Compared with CTV, a combination of CUBE and MRV could provide an improved assessment of the degree of lumen stenosis in May–Thurner syndrome and demonstrate acute thrombosis. MRI underestimates the diameter of the vessel in comparison with CTV. MRI can be a substitute tool for Duplex ultrasound and CTV.

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Association between high-resolution MRI-detected extramural vascular invasion and tumour microcirculation estimated by dynamic contrast-enhanced MRI in rectal cancer: preliminary results

BMC Cancer ◽

10.1186/s12885-019-5732-z ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 2

Author(s):

Yan Chen ◽

Xinyue Yang ◽

Ziqiang Wen ◽

Yiyan Liu ◽

Baolan Lu ◽

...

Keyword(s):

Rectal Cancer ◽

High Resolution ◽

Vascular Invasion ◽

Preliminary Results ◽

Dynamic Contrast Enhanced Mri ◽

Dynamic Contrast Enhanced ◽

Enhanced Mri ◽

Contrast Enhanced ◽

High Resolution Mri ◽

Contrast Enhanced Mri

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High-Resolution MRI of Carotid Plaque With a Neurovascular Coil and Contrast-Enhanced MR Angiography: One-Stop Shopping for the Comprehensive Assessment of Carotid Atherosclerosis

American Journal of Roentgenology ◽

10.2214/ajr.10.4751 ◽

2011 ◽

Vol 196 (5) ◽

pp. 1164-1171 ◽

Cited By ~ 19

Author(s):

Stefano Tartari ◽

Roberto Rizzati ◽

Riccardo Righi ◽

Anna Deledda ◽

Katia Capello ◽

...

Keyword(s):

High Resolution ◽

Carotid Plaque ◽

Mr Angiography ◽

Carotid Atherosclerosis ◽

Comprehensive Assessment ◽

Contrast Enhanced ◽

High Resolution Mri ◽

One Stop

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Diagnostic performance in T staging for patients with esophagogastric junction cancer using high-resolution MRI: a comparison with conventional MRI at 3 tesla

Cancer Imaging ◽

10.1186/s40644-019-0269-6 ◽

2019 ◽

Vol 19 (1) ◽

Author(s):

Yuan Yuan ◽

Luguang Chen ◽

Shengnan Ren ◽

Zhen Wang ◽

Yukun Chen ◽

...

Keyword(s):

High Resolution ◽

Esophagogastric Junction ◽

Diagnostic Performance ◽

Imaging Techniques ◽

3 Tesla ◽

Conventional Mri ◽

Contrast Enhanced ◽

High Resolution Mri ◽

Pathologic Staging ◽

Esophagogastric Junction Cancer

Abstract Background To investigate and compare the diagnostic performance in T staging for patients with esophagogastric junction cancer using high-resolution magnetic resonance imaging (HR MRI), as compared with conventional MRI at 3 Tesla. Methods A total of 118 patients with pathologically confirmed esophagogastric junction cancer were included and underwent multiparameter HR MRI (Cohort 1, 62 patients) or conventional MRI (Cohort 2, 56 patients). T2-weighted, T1-weighted, diffusion-weighted and contrast-enhanced T1-weighted images of each patient were evaluated by two radiologists who determined the preoperative T staging by consensus. Using pathologic staging as the gold standard, the consistency between HR MRI and pathology and between conventional MRI and pathology in T staging was calculated and compared. The overall accuracy, overstatement and understatement of HR MRI and conventional MRI in T staging of patients with esophagogastric junction cancer were computed and compared. Moreover, the diagnostic performance of HR MRI and conventional MRI in T staging (≤ T1 and ≥ T4) of patients with esophagogastric junction cancer were evaluated. Results There were no significant differences in age (p = 0.465) and sex (p = 0.175) between Cohorts 1 and 2. Excellent agreement was observed in the T staging of patients with esophagogastric junction cancer between pathology and HR MRI (kappa = 0.813), while moderate agreement was observed between pathology and conventional MRI (kappa = 0.486). Significant differences were observed in overall accuracy (88.7% vs 64.3%, p = 0.002) and understatement (1.6% vs 26.8%, p < 0.001) but not for overstatement (9.7% vs 8.9%, p = 0.889) in T staging between HR MRI and conventional MRI techniques. For differentiating the T stages of ≤ T1 from ≥ T2 and the T stages of ≤ T3 from ≥ T4, no significant differences were observed between the imaging techniques. Conclusions HR MRI has good diagnostic performance and may serve as an alternative technique in the T staging of patients with esophagogastric junction cancer in clinical practice.

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HIGH-RESOLUTION CONTRAST-ENHANCED MRI IN DIFFERENTIAL DIAGNOSIS OF TYPE OF CAROTID PLAQUE AND IT'S RELATIONSHIP TO THE ISCHEMIC BRAIN DAMAGE

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2013-3-97-105 ◽

2013 ◽

Vol 12 (3) ◽

pp. 97-105

Author(s):

Ye. E. Bobrikova ◽

V. Yu. Ussov ◽

N. V. Shcherban ◽

V. B. Khaneev ◽

T. A. Shelkovnikova ◽

...

Keyword(s):

High Resolution ◽

Atherosclerotic Plaque ◽

Arterial Wall ◽

Significant Rise ◽

Cerebral Stroke ◽

Moderate Increase ◽

Ischemic Brain ◽

Atherosclerotic Lesions ◽

Contrast Enhanced ◽

High Resolution Mri

Aim of the study. We have compared in patients with carotid atherosclerosis the patterns of contrast enhancement of atherosclerotic plaque with presence of cerebral stroke, by using of high-resolution contrast-enhanced carotid MRI.Material and methods. The patients 'population comprised 26 persons with either monolateral (14 pts) or bilateral (12 pts) stenosis of internal carotid artery for over 70% of lumen. In 15 (10-monolateral, 5 bilateral stenosis) there was recent stroke in acute or subacute stage, whereas 11 were symptom-free. In everybody contrast-enhanced study of atherosclerotic plaque was carried out with T1-w high-resolution MRI (paramagnetic as 2 ml of 0.5 mol solution per 10 kg of BW).Results and discussion. In control persons there was a mild increase in T1-w intensity of arterial wall of carotids? With IE not more than 1.08. In patients without stroke there was moderate increase in plaque T-1w intensity up to 1.14 ± 0.07. In ishaemic stroke patients there was significant rise in intensity of T1-w of homolateral plaque (IE = 1.35 ± 0.06), and also of T1-w of arterial wall as whole (IE = 1.19 ± 0.05).Conclusion. Further detailed study of high-resolution MRI of carotids is worth in order to obtain better imaging of atherosclerotic lesions and also better evaluation of risk of stroke in patients suitable for carotid endarterectomy.

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