scholarly journals 375 LARGE-SCALE ASSOCIATION STUDY OF SUSCEPTIBILITY GENES FOR LUMBAR DISC HERNIATION

2009 ◽  
Vol 17 ◽  
pp. S197-S198
Author(s):  
S. Ikegawa
2014 ◽  
Vol 4 (1_suppl) ◽  
pp. s-0034-1376593-s-0034-1376593
Author(s):  
D. Samartzis ◽  
J. Karppinen ◽  
K. DK Luk ◽  
K. MC Cheung

Author(s):  
FANG LIU ◽  
ZHI-WEN ZHU

The lumbar disc has complex structure and material properties, and if it develops disease, it cannot heal itself. Therefore, prevention of lumbar disc herniation is very important. In this paper, the model of lumbar disc is built, and the nonlinear dynamic response of the system is researched. A modified Van der Pol model is imported to describe the stress–strain curves of the lumbar disc. The system’s dynamic model is set up, and harmonic balance method is applied to revise the natural frequency of the system. The product of numerical simulation reveals that the lumbar disc has complex dynamic characteristics, including balance point, limit cycle bifurcation and stochastic Hopf bifurcation. By changing the parameters, we can avoid large-scale periodic movement of the lumbar disc which causes lumbar disc herniation. These results contribute to the prevention of lumbar disc herniation.


2019 ◽  
Vol 12 (2) ◽  
pp. 139-146
Author(s):  
Mladen E. Ovcharov ◽  
Iliya V. Valkov ◽  
Milan N. Mladenovski ◽  
Nikolay V. Vasilev

Summary Lumbar disc herniation (LDH) is the most common pathology in young people, as well as people of active age. Despite sophisticated and new minimally invasive surgical techniques and approaches, reoperations for recurrent lumbar disc herniation (rLDH) could not be avoided. LDH recurrence rates, reported in different studies, range from 5 to 25%. The purpose of this study was to estimate the recurrence rates of LDH after standard discectomy (SD) and microdiscectomy (MD), and compare them to those reported in the literature. Retrospectively, operative reports for the period 2012-2017 were reviewed on LDH surgeries performed at the Neurosurgery Clinic of Dr Georgi Stranski University Hospital in Pleven. Five hundred eighty-nine single-level lumbar discectomies were performed by one neurosurgeon. The diagnoses of recurrent disc herniation were based on the development of new symptoms and magnetic resonance/computed tomography (MRI/CT) images showing compatible lesions in the same lumbar level as the primary lumbar discectomies. The recurrence rate was determined by using chi-square tests and directional measures. SD was the most common procedure (498 patients) followed by MD (91 patients). The cumulative reoperation rate for rLDH was 7.5%. From a total number of reoperations, 26 were males (59.1%) and 18 were females (40.9%). Reoperation rates were 7.6% and 6.6% after SD and MD respectively. The recurrence rate was not significantly higher for SD. Our recurrence rate was 7.5%, which makes it comparable with the rates of 5-25% reported in the literature.


2018 ◽  
Vol 8 (5) ◽  
pp. 14-19
Author(s):  
Tri Truong Van ◽  
Tri Tran Duc Duy ◽  
Khai Vo Le Quang

Introduction: Surgical wound infection in developing coutries is about 3%. Antibiotics prophylaxis may help to reduce the surgical site infection. The objective of this study was to evaluate the efficacy of antibiotics prophylaxis in patients with lumbar disc herniation who were treated with lumbar discectomy at Hue University hospital. Materials and Methods: A prospective study was conducted at Hue University hospital from March 2015 to May 2018 on 54 patients with lumbar disc herniation who were used antibiotics prophylaxis when undergoing discectomy. Results: The infection rate in our study was 0%. Antibiotics prophylaxis reduced the length of hospitalization as well as the medical cost. Conclusion: Antibiotics prophylaxis was effective in preventing surgical site infection despite the fact that the condition of operating rooms did not meet the standard rules. Key words: prophylaxis antibiotics, lumbar disc herniation


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