041 GAIT DISTURBANCE AND FALLS AS INITIAL SIGNS OF NEUROLEPTIC MALIGNANT SYNDROME DUE TO RISPERIDONE: A CASE REPORT

2010 ◽  
Vol 16 ◽  
pp. S13
Author(s):  
A. Gonzalez Ramirez ◽  
V. Mazoteras Muñoz ◽  
J. Martin Marquez ◽  
N. Fernandez Martinez ◽  
G. Martinon Torres ◽  
...  
1986 ◽  
Vol 31 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Margaret Schibuk ◽  
Debbie Schachter

The authors present a case report in which an agitated response to antidepressants preceded the neuroleptic malignant syndrome (NMS). In a review of 64 cases of NMS in the literature, they found that 80% were described as agitated prior to the development of the syndrome. Polypharmacy was common. A review of the literature on theories of pathogenesis involving sympathetic amines other than dopamine is presented to explain this phenomena. It is suggested that these toxic reactions to medication can be interpreted as resulting from a relative NE/DA excess, in which antidepressants increase the numerator, while neuroleptics functionally decrease the denominator. It is recommended that where an agitated response to antidepressants is observed, neuroleptics should be used only with considerable caution.


1996 ◽  
Vol 30 (3) ◽  
pp. 419-421 ◽  
Author(s):  
Richard J. Bonwick ◽  
Malcolm J. Hopwood ◽  
Philip L.R Morris

Objective: To describe a case of neuroleptic malignant syndrome associated with risperidone. Clinical picture: An elderly patient with bipolar affective disorder presented with neuroleptic malignant syndrome and relapse of hypomania after commencing risperidone. Treatment: Risperidone was ceased and the patient monitored closely. Outcome: The symptoms of neuroleptic malignant syndrome were resolved. Conclusion: To our knowledge this is the first such case reported, and suggests that risperidone, like other neuroleptics, is associated with neuroleptic malignant syndrome.


Author(s):  
Tevfik Kalelioglu ◽  
Guler Celikel ◽  
Ozlem Devrim Balaban ◽  
Nesrin Karamustafalioglu ◽  
Jennifer Kim Penberthy

Objective: Neuroleptic malignant syndrome (NMS) is a rare but severe side effect of antipsychotic medication. Neutrophil-lymphocyte ratio (NLR) is a simple marker used to measure systemic inflammation. Method: In this case report we explore the relationship of inflammation in the etiology of NMS. In our case involving NMS, although there was no leukocytosis, the NLR was increased up to systemic infection levels. Conclusion: We hypothesized that systemic inflammation may take a role in developing NMS. If so, NLR could be a new marker of NMS that may be able to provide more sensitive results than leukocyte levels.


2006 ◽  
Vol 21 (4) ◽  
pp. A22
Author(s):  
Makiko Nakagawa ◽  
Takehiko Matsumura ◽  
Daiji Kato ◽  
Chiaki Kawanishi ◽  
Ikuko Kishida ◽  
...  

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