Physiological microassay of plasma total antioxidant status in a model of endothelial dysfunction in the rat following experimental oxidant stress in vivo

Abstract Introduction: Nickel is a strong immunologic sensitizer, although nickel sensitivity has been reported to be lower in subjects who have received orthodontic treatment; perhaps they develop immunological tolerance over the long period of treatment. Hence the present aim of the work was to determine the levels of lipid peroxidation and total antioxidant status in Serum and Saliva in subjects treated with stainless steel Orthodontic appliances. Methods and Materials: The study group included 25 participants and Samples were taken in different time intervals: Time interval 1- Collection of samples before the appliances fixed, Time interval 2- Collection of sample after one week of fixed appliances, Time interval 3- Collection of sample after three months of fixed appliances each from the Orthodontic Department of A. B.Shetty Memorial institute of dental science.Lipid peroxidation (Malondialdehyde) level is estimated using Thiobarbituric acid (TBA) method. Total antioxidant level was estimated using Phosphomolybdenum method. Conclusion: Total antioxidant and Malondialdehyde levels are increased in case of Females compared to Males in serum whereas in case of Saliva Total antioxidant level is increased in Time interval 2 and 3 in Males compared to Females.

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Maternal plasma total antioxidant status in preterm labor

Journal of Obstetrics and Gynaecology Research ◽

10.1111/j.1447-0756.2010.01300.x ◽

2010 ◽

Vol 36 (6) ◽

pp. 1185-1188 ◽

Cited By ~ 8

Author(s):

Aysegül Cinkaya ◽

Hüseyin Levent Keskin ◽

Umran Buyukkagnici ◽

Tayfun Gungor ◽

Esra Aktepe Keskin ◽

...

Keyword(s):

Preterm Labor ◽

Antioxidant Status ◽

Total Antioxidant Status ◽

Maternal Plasma ◽

Total Antioxidant ◽

Plasma Total Antioxidant Status

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Rutin Content in Buckwheat Enriched Bread and Influence of its Consumption on Plasma Total Antioxidant Status

Czech Journal of Food Sciences ◽

10.17221/967-cjfs ◽

2009 ◽

Vol 27 (Special Issue 1) ◽

pp. S236-S240 ◽

Cited By ~ 19

Author(s):

T. Bojňanská ◽

H. Frančáková ◽

P. Chlebo ◽

A. Vollmannová

Keyword(s):

Antioxidant Status ◽

Total Antioxidant Status ◽

Biologically Active ◽

Active Components ◽

Overall Acceptability ◽

Total Antioxidant ◽

Acceptability Rating ◽

Baked Products ◽

Plasma Total Antioxidant Status

The goal of this study is the evaluation of enriched bread prepared with an addition of buckwheat as a source of biologically active components in nutrition. Experimental pastry was baked using buckwheat wholegrain flour blended with wheat flour in different portions (10%, 20%, 30%, 40% and 50%) in order to observe the influence of buckwheat addition on dough processing and the quality of the final baked products. Taking into account the overall acceptability rating, it was concluded that bread with an addition of up to 30% of buckwheat could be baked with satisfactory evaluation results. The content of rutin in loaves in a consumable form prepared with a buckwheat addition varied between 7.76 mg/kg and 26.90 mg/kg. The clinical study which followed the baking experiment was based on the consumption of enriched bread (30% buckwheat, between 34.7 mg/kg and 38.2 mg/kg rutin content in dry matter) by a group of volunteers during a period of four weeks. The results approved the increase of the total antioxidant status thanks to the buckwheat enriched bread consumption from the value of 1.135 ± 0.066 mmol/dm<sup>3</sup> at the beginning of the study to 1.46 ± 0.083 mmol/dm<sup>3</sup> at the end of the study, i.e. significant differences.

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Reduced plasma total antioxidant status in first-episode drug-naive patients with schizophrenia

Progress in Neuro-Psychopharmacology and Biological Psychiatry ◽

10.1016/j.pnpbp.2011.03.001 ◽

2011 ◽

Vol 35 (4) ◽

pp. 1064-1067 ◽

Cited By ~ 28

Author(s):

Xue Feng Li ◽

You Lan Zheng ◽

Mei Hong Xiu ◽

Da Chun Chen ◽

Thomas R. Kosten ◽

...

Keyword(s):

Antioxidant Status ◽

Total Antioxidant Status ◽

First Episode ◽

Total Antioxidant ◽

Drug Naïve ◽

Plasma Total Antioxidant Status

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Effects of commonly used medicinal herbs in Jordan on serum total antioxidant status and clinical laboratory testing

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v10i4.1723 ◽

2019 ◽

Vol 10 (4) ◽

pp. 3489-3497

Author(s):

Yousif. Y. Bilto ◽

Nessrin. G. Alabdallat ◽

Ali. M. Atoom ◽

Noaman. A. Khalaf

Keyword(s):

Oral Administration ◽

Laboratory Testing ◽

Antioxidant Status ◽

Clinical Chemistry ◽

Total Antioxidant Status ◽

Medicinal Herbs ◽

Aqueous Extracts ◽

Total Antioxidant ◽

Clinical Chemistry Tests

The use of medicinal herbs is widespread and growing. We tested the in-vivo effects of commonly used medicinal herbs in Jordan, on normal human volunteers after oral administration of aqueous extracts for several days, to see whether the in-vitro chemical antioxidant activity of a given herb replicates in-vivo and to see whether a given medicinal herb affects the results of selected clinical chemistry tests performed on the serum. Healthy volunteers were given orally aqueous herbal extracts daily for five days. Venous blood samples were taken before and one hour after the first dose of aqueous extract and then one day after the last dose of day five. Total antioxidant status and 13 of routine clinical chemistry tests were assayed on the serum. The tested herbs caused a significant increase in serum total antioxidant status. The studied herbs can be arranged in decreasing order of their in-vivo antioxidant strength after one hour of first consumption as follows: Nigella sativum > Rosmarinus officinalis > Zingiber officinale > Verbena triphylla > Origanum syriacum > Salvia triloba. The studied herbs except for Rosmarinus officinalis also caused a significant increase and/or decrease in 10 out of 13 laboratory tests performed on the serum. These results indicate that oral administration of aqueous extracts of medicinal herbs although improve the serum total antioxidant status, they could also significantly alter some laboratory results used for diagnosis or evaluation of diseases and this may negatively affect patient’s care. The present study highlights the importance of obtaining information regarding patients’ uptake of herbal products that might interfere with some laboratory testing.

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