Genotoxicity and antigenotoxicity of some essential oils evaluated by wing spot test of Drosophila melanogaster

Author(s):  
M Idaomar ◽  
R El Hamss ◽  
F Bakkali ◽  
N Mezzoug ◽  
A Zhiri ◽  
...  
Author(s):  
Maria Eugenia Heres-Pulido ◽  
Samantha Lombera-Hernández ◽  
Irma Dueñas-García ◽  
Ivonne Perales-Canales ◽  
Laura Castañeda-Partida ◽  
...  

Author(s):  
Mercedes M N Reynoso ◽  
Alejandro Lucia ◽  
Eduardo N Zerba ◽  
Raúl A Alzogaray

Abstract Eugenol is a major component of the essential oils in cloves and other aromatic plants. In insects, it produces toxic effects and repellency, and there is evidence that its site of action is the octopamine receptor. The objective of the present study was to explore whether the octopamine receptor is involved in the hyperactivity produced by eugenol in the blood-sucking bug Triatoma infestans (Klug). This insect is the main vector of Chagas disease in Latin America. Four treatments were topically applied on third instar nymphs: 1) octopamine, 2) eugenol, 3) phentolamine hydrochloride (an antagonist of the octopamine receptor) followed by octopamine, and 4) phentolamine hydrochloride followed by eugenol. Both octopamine and eugenol hyperactivated the nymphs. However, pretreatment with phentolamine hydrochloride inhibited the hyperactivating effect of both compounds. These results are in agreement with previous works on Drosophila melanogaster (Meigen) (Diptera: Drosophilidae) and the American cockroach. They suggest that the octopamine receptor is a possible site of action for eugenol.


2015 ◽  
Vol 18 (10) ◽  
pp. 1136-1142 ◽  
Author(s):  
Zaira Rosa Guterres ◽  
Thalita Alves Zanetti ◽  
Tiago Felipe Sennes-Lopes ◽  
Ana Francisca Gomes da Silva

Eisei kagaku ◽  
1995 ◽  
Vol 41 (6) ◽  
pp. 452-457 ◽  
Author(s):  
TAKAHIKO SATO ◽  
HAJIME NISHINO ◽  
HISAMITSU NAGASE ◽  
MIKI NIIKAWA ◽  
HIDEAKI KITO

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