Abstract #251: Correlation of Left Ventricular Hypertrophy & Left Ventricular Diastolic Dysfunction with HBA1C in Newly Diagnosed Type 2 Diabetics

2015 ◽  
Vol 21 ◽  
pp. 49-50
Author(s):  
Manish Gutch ◽  
Syed Razi ◽  
Sukriti Kumar ◽  
Keshav Gupta
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Diastolic Dysfunction ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Newly Diagnosed ◽  
Type 2 Diabetics ◽  
Ventricular Diastolic Dysfunction

The Association between Left Ventricle Diastolic Dysfunction and Endothelial Dysfunction and the Results of Stress Myocardial SPECT in Asymptomatic Patients with Type 2 Diabetes

2005 ◽  
Vol 33 (5) ◽  
pp. 473-482 ◽  
Author(s):  
J Charvát ◽  
K Michalova ◽  
J Chlumský ◽  
Z Valenta ◽  
M Kvapil
Keyword(s):  
Type 2 Diabetes ◽  
Left Ventricular Hypertrophy ◽  
Diastolic Dysfunction ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Myocardial Spect ◽  
Asymptomatic Patients ◽  
Ventricular Diastolic Dysfunction

Diabetes mellitus is associated with a poor cardiovascular prognosis. Stress myocardial single-photon emission computed tomography (SPECT) reliably detects coronary ischaemia in asymptomatic patients. Our study aimed to evaluate the association between systolic and diastolic left ventricular function, left ventricular hypertrophy, endothelial function and the results of stress myocardial SPECT in 126 patients with type 2 diabetic patients with no cardiovascular symptoms. Thirty-three patients (26%) had abnormal SPECT results, 33 patients (26%) had intermediate (equivocal) results, and 60 patients (48%) had normal results. We found a significant association between an abnormal SPECT result, left ventricular diastolic dysfunction and impaired post-ischaemic dilatation of the brachial artery. No association was found between the SPECT result and systolic function and left ventricular hypertrophy, however. An abnormal SPECT result was significantly associated with left ventricular diastolic dysfunction and the deterioration of post-ischaemic dilatation of the brachial artery in asymptomatic patients with type 2 diabetes.

scholarly journals Correlation between left ventricular diastolic dysfunction and dyslipidaemia in asymptomatic patients with new-onset type 2 diabetes mellitus

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
K. M. Hassan Ayman ◽  
A. Abdallah Mahmoud ◽  
A. Abdel-Mageed Eman ◽  
Sayed Marwa ◽  
M. Soliman Mona ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Diabetic Patients ◽  
Newly Diagnosed ◽  
Type 2 Dm ◽  
Asymptomatic Patients ◽  
Ventricular Diastolic Dysfunction ◽  
New Onset

Abstract Background Poor glycaemic control is associated with a greater risk of development of heart failure in diabetic patients. We aimed to study the prevalence of left ventricular (LV) systolic and diastolic dysfunction in asymptomatic patients with new-onset type 2 DM. We conducted a cross-sectional study including patients with newly diagnosed (within 1 year) type 2 DM; all patients were between the ages of 30 and 60 years, normotensive and clinically asymptomatic and attended the outpatient clinic of the endocrinology unit at a university hospital between March 2016 and June 2017. Demographic characteristics, clinical risk factors and waist-hip ratio (WHR) were assessed. Blood samples for laboratory analysis were obtained. Detailed echocardiography was performed to evaluate systolic and diastolic function. Results A total of 100 patients were included. Sixty-one percent had diastolic dysfunction with preserved ejection fraction. Left ventricular diastolic dysfunction (LVDD) was more prevalent in diabetic patients with HbA1c ≥ 8.1 (75%) Patients with LVDD had significant dyslipidaemia in comparison to those without LVDD. Multivariate logistic regression analysis showed that WHR and HbA1c levels are the only predictors of impaired diastolic function in patients with new-onset DM. Kaplan-Meier survival curves showed a significant correlation between the incidence of diastolic dysfunction and the duration of DM, with higher incidence with HbA1c ≥ 8.1. Conclusions Diastolic dysfunction is highly prevalent in patients with newly diagnosed DM and is positively correlated with HbA1c level, obesity, dyslipidaemia and the duration of diabetes.

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