Abstract # P-13: Characteristics of Korean T2DM Patients with Diabetic Retinopathy and Macular Edema: A Study Based on a Standardized Clinical Data

Purpose To investigate the clinical effects and outcomes of intravitreal injection of 4 mg of triamcinolone acetonide (IVTA) after or concomitant with macular laser photocoagulation (MP) for clinically significant macular edema (CSME). Methods Forty-nine eyes of 49 patients with nonproliferative diabetic retinopathy and CSME were randomized into three groups. The eyes in the laser group (n=17), group 1, were subjected to MP 3 weeks after IVTA; the eyes in the IVTA group (n=13), group 2, were subjected to MP, concomitant with IVTA; the eyes in the control group (n=19), group 3, underwent only IVTA application. Visual acuity (VA), fundus fluorescein angiography, and photography were performed in each group. Results In the first group, the mean VA improved from 0.17±0.09 at baseline to 0.28±0.15 (p=0.114) and in the second group, deteriorated from 0.19±0.08 at baseline to 0.14±0.08 at the sixth month (p=0.141), respectively. In Group 3, the mean VA improved from 0.16±0.08 at baseline to 0.28±0.18 (p=0.118) at the end of the follow-up. When VA was compared between the control and study groups, significant difference was detected at the sixth month (p=0.038). Conclusions MP after IVTA improved VA, rather than MP concomitant with IVTA, and only IVTA application for CSME. MP after IVTA may reduce the recurrence of CSME and needs further investigations in a longer period.

Download Full-text

Diabetic retinopathy with or without clinically significant macular edema: The influencing factors

Nepalese Journal of Ophthalmology ◽

10.3126/nepjoph.v7i2.14964 ◽

2016 ◽

Vol 7 (2) ◽

pp. 142-147

Author(s):

Barsha Suwal ◽

Jeevan Kumar Shrestha ◽

Sagun Narayan Joshi ◽

Ananda Kumar Sharma

Keyword(s):

Diabetic Retinopathy ◽

Glycemic Control ◽

Macular Edema ◽

Total Cholesterol ◽

Cholesterol Level ◽

Total Cholesterol Level ◽

Density Lipoprotein ◽

Diabetic Patients ◽

Clinically Significant Macular Edema ◽

Clinically Significant

Introduction: Diabetic retinopathy is the commonest micro vascular complication in patients with diabetes and remains a leading cause of blindness in people of working age group. Objective: to determine the prevalence of clinically significant macular edema (CSME) and the influence of systemic risk factors Materials and methods: It is a hospital based comparative study conducted in 220 eyes of 110 diabetic patients. DR was graded according to International Clinical Diabetic Retinopathy Severity Scale and CSME was defined according to Early Treatment Diabetic Retinopathy Study (ETDRS) system. The patients were grouped as 1) CSME group (DR and CSME in one or both eyes) and 2) Non- CSME group(CSME in none of the eyes but with any grade of DR).Level of glycosylated hemoglobin (HbA1C), serum total cholesterol, triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and urine for albumin were studied in both groups. Results: CSME was present in 36% of 110 patients. Poor glycemic control and high total cholesterol level showed positive association with CSME (p<0.05). LDL and TG levels were higher and HDL lower in CSME group. However, no statistical significance was found. Conclusion: The CSME is significantly associated with poorer glycemic control and elevated total cholesterol level.

Download Full-text

Localization of macular edema region from color retinal images for detection of diabetic retinopathy

2017 International Artificial Intelligence and Data Processing Symposium (IDAP) ◽

10.1109/idap.2017.8090174 ◽

2017 ◽

Author(s):

Umit Budak ◽

Abdulkadir Sengur ◽

Yaman Akbulut

Keyword(s):

Diabetic Retinopathy ◽

Macular Edema ◽

Retinal Images

Download Full-text

Treatment of cystoid macular edema in a patient with primary open angle glaucoma and diabetic retinopathy by withdrawal of travoprost

IP International Journal of Ocular Oncology and Oculoplasty ◽

10.18231/j.ijooo.2021.035 ◽

2021 ◽

Vol 7 (2) ◽

pp. 180-183

Author(s):

Shiv Sagar N ◽

BN Kalpana ◽

Shilpa YD

Keyword(s):

Diabetic Retinopathy ◽

Macular Edema ◽

Laser Treatment ◽

Proliferative Diabetic Retinopathy ◽

Cystoid Macular Edema ◽

Open Angle Glaucoma ◽

Eye Drops ◽

Antiglaucoma Medication ◽

Micropulse Laser

To study the association of cystoid macular edema (CME) and Travoprost eye drops in a patient with diabetic retinopathy (DR).The study was carried out on a 65yr old patient on a regular follow up from 2009-2018.A 65yr old patient of a DR of both eyes who had received 3 sittings of pan retinal photocoagulation (PRP) laser in both eyes and grid laser to his right eye. He was on regular follow up since 2009 with a stable proliferative diabetic retinopathy (PDR). Patient was also on topical antiglaucoma medication and had prophylactic YAG-PI done both eyes. He was on regular follow up since 2009 with a stable proliferative diabetic retinopathy (PDR). Right eye showed macular edema (ME) in 2014 and underwent OCT and FFA. Patient refused for intravitreal injection and preferred laser treatment, so patient underwent micropulse laser treatment in 2014. His edema persisted even after micropulse treatment. His systemic control was good and patient continued to use Travoprost eye drops. So in 2017 suspected CME secondary to topical prostaglandin (PG) analogue as he had strict glycemic control and was no fluctuation in ME. Hence topical PG analogue was withdrawn and stopped. On subsequent follow up after 2 months CME had completely disappeared and the foveal contour returned to normal on OCT. LE was status quo. Patient was followed up for more than 1 year and continuously followed up, 15 days back in June 2018 had no evidence of CME and vision was 6/9 in both eyes.: Differentiation of DME and CME secondary to PG analogue should be made at the earliest.

Download Full-text