825 NEUROIMAGING ALTERATIONS IN TYPE 2 DIABETES MELLITUS: CORRELATIONS WITH BIOCHEMICAL AND ANTHROPOMETRIC PARAMETERS

2011 ◽  
Vol 12 (1) ◽  
pp. 173
Author(s):  
N. García-Casares ◽  
M.L. Berthier ◽  
J. Rioja ◽  
J.A. Garcia-Arnés ◽  
A. Gutiérrez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Anthropometric Parameters

scholarly journals COMPARISON OF THE EFFECT OF DAPAGLIFLOZIN ON CONTRAST TO STANDARD THERAPY OF THE PATIENTS WITH TYPE 2 DIABETES MELLITUS AND CONCOMITANT OBESITY, THEIR EFFECT ON LABORATORY AND ANTHROPOMETRIC PARAMETERS

2020 ◽  
Vol 73 (3) ◽  
pp. 457-461
Author(s):  
Taras I. Griadil ◽  
Ivan V. Chopey ◽  
Kristian O. Debreceni ◽  
Mykhaylo M. Hechko ◽  
Yaroslav O. Mykhalko ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Laboratory ◽  
Glycosylated Hemoglobin ◽  
Anthropometric Parameters ◽  
Metformin Monotherapy ◽  
Effect Of Glucose ◽  
Standard Treatment Regimen

The aim: Evaluate clinical and laboratory parameters of the patients with type 2 diabetes mellitus and concomitant obesity after a course of dapagliflozin treatment and compare with a standard treatment regimen. Materials and methods: Conducted a comprehensive clinical laboratory examination and measurement of the anthropometric parameters of the patients with type 2 diabetes mellitus and concomitant obesity, with subsequent statistical calculations. Results: The data obtained at different stages of the study revealed a statistically significant effect of glucose treatment and glycosylated hemoglobin (HbA1c). Since the 6th month of dapagliflozin treatment, we have shown a tendency to lose weight compared to baseline in this group of patients and controls. Conclusions: Type 2 diabetes mellitus and obesity significantly increase the risk of developing a number of complications. Complex control and effects on clinical laboratory and anthropometric parameters can statistically significantly influence the development of the complications, and in this context, dapaglifloflozin showed statistically better results than standard metformin monotherapy.

scholarly journals The association of anthropometric parameters with markers of insulin and leptin secretion and resistance in type 2 diabetes mellitus

2020 ◽  
Vol 28 (3) ◽  
pp. 299-314
Author(s):  
Simona Cernea ◽  
Emőke Both ◽  
Adriana Fodor
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion ◽  
Diabetes Duration ◽  
Leptin Resistance ◽  
Anthropometric Parameters ◽  
C Peptide

AbstractAim: We evaluated the association between anthropometric parameters and markers of insulin and leptin secretion/resistance in patients with type 2 diabetes mellitus (T2DM).Material and methods: This post-hoc data analysis from a cross-sectional study included 176 T2DM patients. Laboratory tests (serum leptin, soluble form of leptin receptor (sObR), C peptide, glycemic and lipid parameters) and anthropometric parameters were obtained, adiposity indexes (including body adiposity index (BAI), visceral adiposity index (VAI)), indicators of insulin resistance, β-cell function, and leptin resistance (Free Leptin Index, FLI) were calculated.Results: The body mass index (BMI), diabetes duration, VAI and leptin correlated independently with HOMA-IR, while BMI, diabetes duration and HbA1c with HOMA-B. The total body fat mass (TBFM), C peptide, diabetes duration, BMI and BAI correlated with leptin concentrations, while the first three with FLI. VAI was an indicator of insulin resistance (β=0.166, p=0.003), while BAI of leptin secretion (β=0.260, p=0.010). TBFM strongly associated with leptin resistance and secretion (β=0.037, r=0.688, p<0.0001, and β=0.521, r=0.667, p<0.0001), and BMI correlated weakly with insulin secretion and resistance. While insulin and leptin secretion increased progressively with BMI, leptin and insulin resistance became significant only in case of obesity. The sObR was significantly associated with C peptide concentrations (β=-0.032; p=0.044), but not with HOMA-B or -IR. A strong positive correlation between the C peptide/leptin ratio and non-fat mass /TBFM ratio was noted (r=0.62 [0.52, 0.71], p<0.0001).Conclusions: Parameters of peripheral adiposity correlated better with markers of leptin system, and those of visceral adiposity with markers of insulin secretion/resistance. The sObR correlated independently and negatively with C peptide.

scholarly journals Relation between waist-hip ratio and lipid profile in type 2 diabetes mellitus patients

2014 ◽  
Vol 5 (3) ◽  
pp. 51-53
Author(s):  
Pillaram Raja Reddy ◽  
N Jayarama ◽  
M Madhavi Reddy ◽  
V Mahesh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Pearson Correlation ◽  
Medical Science ◽  
Diabetic Patients ◽  
Anthropometric Parameters ◽  
Waist Hip Ratio

Objective: To observe the relation between waist-hip ratio and lipid profile in type 2 diabetes mellitus patients. Materials and Methods: The present study was carried out at R L Jalappa Hospital attached to Sri DevaRaj Urs Medical College, Tamaka, Kolar, after a written consent from all the participants. The study includes 505 diabetic patients, in which 336 were males and 169 were females. The waist and hip circumference were measured and the ratio was taken as Waist-Hip ratio and about 5 ml of blood sample was collected and used for the estimation of serum cholesterol, triglyceride and HDL-Cholesterol levels by using standard methods. Statistical analysis was done by using independent student t test and Pearson Correlation coefficient was calculated. Results: The waist hip ratio and lipid profiles were not significantly correlated. In type 2 diabetes male patients showed higher triglycerides (177.96±100.19) with waist hip ratio>0.9, whereas female patients showed less Triglycerides (178.19±99.52) with waist hip ratio >0.8. However these differences were statistically not significant. Conclusion: Multiple anthropometric parameters are required to correlate lipid profile rather than single parameter in type 2 diabetes mellitus. Along with anthropometric measurements, lipid profile is also need be monitored in type 2 diabetics. Asian Journal of Medical Science, Volume-5(3) 2014: 51-53 http://dx.doi.org/10.3126/ajms.v5i3.9407     

Sign in / Sign up

Export Citation Format

Share Document