scholarly journals 596: Wnt/b-catenin and sonic hedgehog signaling affect airway basal cell specification of cell types that contribute to CFTR-mediated anion transport

2021 ◽  
Vol 20 ◽  
pp. S284
Author(s):  
Q. Cai ◽  
M. Luo ◽  
F. Yuan ◽  
G. Gasser ◽  
X. Liu ◽  
...  
Keyword(s):  
Sonic Hedgehog ◽  
Basal Cell ◽  
Hedgehog Signaling ◽  
Cell Types ◽  
Anion Transport ◽  
Sonic Hedgehog Signaling ◽  
Cell Specification

scholarly journals Expression profile of sonic hedgehog signaling-related molecules in basal cell carcinoma

PLoS ONE ◽  
2019 ◽  
Vol 14 (11) ◽  
pp. e0225511 ◽  
Author(s):  
Hye Sung Kim ◽  
Young Sil Kim ◽  
Chul Lee ◽  
Myung Soo Shin ◽  
Jae Wang Kim ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Sonic Hedgehog ◽  
Expression Profile ◽  
Basal Cell ◽  
Hedgehog Signaling ◽  
Sonic Hedgehog Signaling

Sonic hedgehog signaling at gastrula stages specifies ventral telencephalic cells in the chick embryo

Development ◽  
2000 ◽  
Vol 127 (15) ◽  
pp. 3283-3293 ◽  
Author(s):  
L. Gunhaga ◽  
T.M. Jessell ◽  
T. Edlund
Keyword(s):  
Sonic Hedgehog ◽  
Neural Tube ◽  
Hedgehog Signaling ◽  
Early Stage ◽  
Primitive Streak ◽  
Cell Types ◽  
Neural Cells ◽  
Sonic Hedgehog Signaling ◽  
Ventral Telencephalon ◽  
Prechordal Mesoderm

A secreted signaling factor, Sonic hedgehog (Shh), has a crucial role in the generation of ventral cell types along the entire rostrocaudal axis of the neural tube. At caudal levels of the neuraxis, Shh is secreted by the notochord and floor plate during the period that ventral cell fates are specified. At anterior prosencephalic levels that give rise to the telencephalon, however, neither the prechordal mesoderm nor the ventral neural tube expresses Shh at the time that the overt ventral character of the telencephalon becomes evident. Thus, the precise role and timing of Shh signaling relevant to the specification of ventral telencephalic identity remains unclear. By analysing neural cell differentiation in chick neural plate explants we provide evidence that neural cells acquire molecular properties characteristic of the ventral telencephalon in response to Shh signals derived from the anterior primitive streak/Hensen's node region at gastrula stages. Exposure of prospective anterior prosencephalic cells to Shh at this early stage is sufficient to initiate a temporal program of differentiation that parallels that of neurons generated normally in the medial ganglionic eminence subdivision of the ventral telencephalon.

Sonic hedgehog signaling in basal cell carcinomas

2005 ◽  
Vol 225 (2) ◽  
pp. 181-192 ◽  
Author(s):  
Leela Daya-Grosjean ◽  
Sophie Couvé-Privat
Keyword(s):  
Sonic Hedgehog ◽  
Basal Cell ◽  
Hedgehog Signaling ◽  
Sonic Hedgehog Signaling ◽  
Basal Cell Carcinomas

scholarly journals Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development

PLoS Genetics ◽  
2016 ◽  
Vol 12 (7) ◽  
pp. e1006151 ◽  
Author(s):  
Carolina N. Perdigoto ◽  
Katherine L. Dauber ◽  
Carmit Bar ◽  
Pai-Chi Tsai ◽  
Victor J. Valdes ◽  
...  
Keyword(s):  
Sonic Hedgehog ◽  
Hedgehog Signaling ◽  
Merkel Cell ◽  
Sonic Hedgehog Signaling ◽  
Cell Specification ◽  
Skin Development

scholarly journals Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome

2014 ◽  
Vol 74 (18) ◽  
pp. 4967-4975 ◽  
Author(s):  
Mohammad Athar ◽  
Changzhao Li ◽  
Arianna L. Kim ◽  
Vladimir S. Spiegelman ◽  
David R. Bickers
Keyword(s):  
Sonic Hedgehog ◽  
Basal Cell ◽  
Hedgehog Signaling ◽  
Sonic Hedgehog Signaling ◽  
Basal Cell Nevus Syndrome
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