Laparoscopic retroperitoneal lymphadenectomy - a routine therapeutic modality in the treatment of nonseminomatons testis cancer stage I

2002 ◽  
Vol 1 (1) ◽  
pp. 94
Author(s):  
Ingolf Tuerk ◽  
John Davis ◽  
Serdar Deger ◽  
Bernd Schönberger ◽  
Paul Schellhammer ◽  
...  
Keyword(s):  
Stage I ◽  
Therapeutic Modality ◽  
Testis Cancer ◽  
Cancer Stage ◽  
Retroperitoneal Lymphadenectomy

Orchiectomy alone in clinical stage I nonseminomatous testis cancer: a critical appraisal.

1986 ◽  
Vol 4 (1) ◽  
pp. 35-40 ◽  
Author(s):  
G Pizzocaro ◽  
F Zanoni ◽  
A Milani ◽  
R Salvioni ◽  
L Piva ◽  
...  
Keyword(s):  
Testicular Cancer ◽  
Clinical Stage ◽  
Stage I ◽  
Testis Cancer ◽  
Retroperitoneal Lymphadenectomy ◽  
Peritumoral Vascular Invasion ◽  
Serum Alpha Fetoprotein ◽  
A Prospective Study ◽  
To Receive ◽  
Disease Free

Sixty-two consecutive patients with clinical stage I nonseminomatous testicular cancer were entered into a prospective study to receive no treatment after orchiectomy until clinical evidence of recurrent disease. Of 59 evaluable cases, 41 (69.5%) remained continuously disease free for a median duration of 30 months (range, 18 to 46 months), and evidence of metastatic disease developed in 18 patients (30.5%) from 2 to 36 months after orchiectomy. The median disease-free interval for relapsing patients was 6 months. Retroperitoneal metastases developed in ten patients; seven patients had pulmonary metastases, and one patient had progressive elevation of the serum alpha-fetoprotein level. Relapses were significantly more frequent in patients with either embryonal carcinoma, infiltrating testicular cancer (pT greater than 1), peritumoral vascular invasion, or in those who underwent transscrotal biopsy. One patient with relapse refused salvage therapy and died. The remaining 17 patients have been rendered disease free with cisplatin combination chemotherapy and/or surgery. However, two patients showed further recurrence, with one in the lung and the other one also in the retroperitoneal nodes. In our opinion, surveillance following orchiectomy will provide useful information in clinical stage I nonseminomatous testicular cancer, but it is a difficult study. For the time being, it should be restricted to specialized centers only. In the meanwhile, retroperitoneal lymphadenectomy remains the standard treatment.

Complications of primary nerve-sparing retroperitoneal lymphadenectomy in clinical stage I nonseminatous testis cancer

2002 ◽  
Vol 1 (1) ◽  
pp. 95 ◽  
Author(s):  
Axel Heidenreich ◽  
Peter Albers ◽  
Köhrmann Kai Uwe ◽  
Susanne Krege ◽  
Tobis Pottek ◽  
...  
Keyword(s):  
Clinical Stage ◽  
Stage I ◽  
Nerve Sparing ◽  
Testis Cancer ◽  
Retroperitoneal Lymphadenectomy

scholarly journals Survival rates and prognostic factors in right- and left-sided colon cancer stage I–IV: an unselected retrospective single-center trial

2021 ◽  
Author(s):  
Claudius E. Degro ◽  
Richard Strozynski ◽  
Florian N. Loch ◽  
Christian Schineis ◽  
Fiona Speichinger ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Overall Survival ◽  
Blood Level ◽  
Proportional Hazards ◽  
Survival Rates ◽  
Cox Proportional Hazards ◽  
Stage I ◽  
Cancer Stage ◽  
Single Center ◽  
Significant Difference

Abstract Purpose Colorectal cancer revealed over the last decades a remarkable shift with an increasing proportion of a right- compared to a left-sided tumor location. In the current study, we aimed to disclose clinicopathological differences between right- and left-sided colon cancer (rCC and lCC) with respect to mortality and outcome predictors. Methods In total, 417 patients with colon cancer stage I–IV were analyzed in the present retrospective single-center study. Survival rates were assessed using the Kaplan–Meier method and uni/multivariate analyses were performed with a Cox proportional hazards regression model. Results Our study showed no significant difference of the overall survival between rCC and lCC stage I–IV (p = 0.354). Multivariate analysis revealed in the rCC cohort the worst outcome for ASA (American Society of Anesthesiologists) score IV patients (hazard ratio [HR]: 16.0; CI 95%: 2.1–123.5), CEA (carcinoembryonic antigen) blood level > 100 µg/l (HR: 3.3; CI 95%: 1.2–9.0), increased lymph node ratio of 0.6–1.0 (HR: 5.3; CI 95%: 1.7–16.1), and grade 4 tumors (G4) (HR: 120.6; CI 95%: 6.7–2179.6) whereas in the lCC population, ASA score IV (HR: 8.9; CI 95%: 0.9–91.9), CEA blood level 20.1–100 µg/l (HR: 5.4; CI 95%: 2.4–12.4), conversion to laparotomy (HR: 14.1; CI 95%: 4.0–49.0), and severe surgical complications (Clavien-Dindo III–IV) (HR: 2.9; CI 95%: 1.5–5.5) were identified as predictors of a diminished overall survival. Conclusion Laterality disclosed no significant effect on the overall prognosis of colon cancer patients. However, group differences and distinct survival predictors could be identified in rCC and lCC patients.

MP-15.21 Two Decades Experience with Single Cycle Adjuvant Chemotherapy in Stage I Non-seminomatous Testis Cancer

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S145-S146
Author(s):  
L. Ebel ◽  
D. Corti ◽  
A. Foneron ◽  
L. Troncoso
Keyword(s):  
Adjuvant Chemotherapy ◽  
Stage I ◽  
Testis Cancer ◽  
Single Cycle

scholarly journals The Causes of Deaths Occurred in Patients of Early Stage Laryngeal Cancer (Stage I, Stage II)

2005 ◽  
Vol 17 (1) ◽  
pp. 11-16
Author(s):  
Mioko Matsuo ◽  
Fumihide Rikimaru ◽  
Satoshi Tou ◽  
Yuuichirou Higaki ◽  
Kichinobu Tomita
Keyword(s):  
Laryngeal Cancer ◽  
Early Stage ◽  
Stage I ◽  
Stage Ii ◽  
Cancer Stage ◽  
Causes Of Deaths
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