Transcriptional targeting of adenoviral vectors to prostate cancer in vitro

2003 ◽  
Vol 2 (6) ◽  
pp. 82
Author(s):  
R KRAAIJ
Keyword(s):  
Prostate Cancer ◽  
Adenoviral Vectors ◽  
Transcriptional Targeting

851 Transcriptional targeting of adenoviral vectors to prostate cancer in vitro

2004 ◽  
Vol 3 (2) ◽  
pp. 215
Author(s):  
R. Kraaij ◽  
L. Van der Weel ◽  
J. Zweistra ◽  
C. De Ridder ◽  
A. Van Rijswijk ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Adenoviral Vectors ◽  
Transcriptional Targeting

Transcriptional targeting of adenoviral vectors to prostate cancer in vitro

2003 ◽  
Vol 2 (6) ◽  
pp. 64
Author(s):  
Robert Kraaij ◽  
Laura van der Weel ◽  
Joke L.M Zweistra ◽  
Corrina M.A de Ridder ◽  
Angélique L.C.T van Rijswijk ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Adenoviral Vectors ◽  
Transcriptional Targeting

scholarly journals Transductional targeting of adenoviral vectors to prostate cancer in vitro

1999 ◽  
Vol 2 (S3) ◽  
pp. S5-S5 ◽  
Author(s):  
CH Bangma ◽  
R Kraaij ◽  
A van Rijswijk ◽  
HJ Haisma ◽  
V van Beusechem ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Adenoviral Vectors

794: Valproic Acid Inhibits Prostate Cancer Cell Growth in Vitro and in Vivo

2006 ◽  
Vol 175 (4S) ◽  
pp. 257-257
Author(s):  
Jennifer Sung ◽  
Qinghua Xia ◽  
Wasim Chowdhury ◽  
Shabana Shabbeer ◽  
Michael Carducci ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Valproic Acid ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth

In vitro studies reveal a potential therapeutic role of the combination of biguanides and statins for the treatment of prostate cancer

2018 ◽  
Author(s):  
Vicente Herrero-Aguayo ◽  
Juan M Jimenez-Vacas ◽  
Enrique Gomez-Gomez ◽  
Antonio J Leon-Gonzalez ◽  
Prudencio Saez-Martinez ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
In Vitro Studies ◽  
Therapeutic Role ◽  
Potential Therapeutic Role

Synthesis, Antiproliferative, and Antiangiogenic Activities of Benzochromene and Benzoquinoline Derivatives on Prostate Cancer in vitro

2017 ◽  
Vol 14 (4) ◽  
pp. 398-413 ◽  
Author(s):  
Gricelda Mata ◽  
Juan Rodrigues ◽  
Neira Gamboa ◽  
Katiuska Charris ◽  
Gricela Lobo ◽  
...  
Keyword(s):  
Prostate Cancer

scholarly journals MicroRNA-144 Suppresses Prostate Cancer Growth and Metastasis by Targeting EZH2

2021 ◽  
Vol 20 ◽  
pp. 153303382198981
Author(s):  
Xin-bo Sun ◽  
Yong-wei Chen ◽  
Qi-sheng Yao ◽  
Xu-hua Chen ◽  
Min He ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Viability ◽  
Cell Apoptosis ◽  
Epithelial Mesenchymal Transition ◽  
Luciferase Reporter ◽  
Mesenchymal Transition ◽  
Proliferation And Apoptosis ◽  
High Incidence ◽  
Inhibit Cell Proliferation

Background: Prostate cancer is a common malignant tumor with a high incidence. MicroRNAs (miRNAs) have been shown to be important post-transcriptional regulators during tumorigenesis. This study aimed to explore the effect of miR-144 on PCa proliferation and apoptosis. Material and Methods: The expression of miR-144 and EZH2 were examined in clinical PCa tissues. PCa cell line LNCAP and DU-145 was employed and transfected with miR-144 mimics or inhibitors. The correlation between miR-144 and EZH2 was verified by luciferase reporter assay. Cell viability, apoptosis and migratory capacity were detected by CCK-8, flow cytometry assay and wound healing assay. The protein level of EZH2, E-Cadherin, N-Cadherin and vimentin were analyzed by western blotting. Results: miR-144 was found to be negatively correlated to the expression of EZH2 in PCa tissues. Further studies identified EZH2 as a direct target of miR-144. Moreover, overexpression of miR-144 downregulated expression of EZH2, reduced cell viability and promoted cell apoptosis, while knockdown of miR-144 led to an inverse result. miR-144 also suppressed epithelial-mesenchymal transition level of PCa cells. Conclusion: Our study indicated that miR-144 negatively regulate the expression of EZH2 in clinical specimens and in vitro. miR-144 can inhibit cell proliferation and induce cell apoptosis in PCa cells. Therefore, miR-144 has the potential to be used as a biomarker for predicting the progression of PCa.

Novel daidzein molecules exhibited anti-prostate cancer activity through nuclear receptor ERβ modulation, in vitro and in vivo studies

2021 ◽  
pp. 1-13
Author(s):  
R. Ranjithkumar ◽  
K. Saravanan ◽  
B. Balaji ◽  
S. Hima ◽  
S. Sreeja ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Nuclear Receptor ◽  
In Vivo Studies ◽  
Cancer Activity
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