47 Diagnostic validation of urinary Tyr-phosphorylated proteins as a new marker for bladder cancer

2014 ◽  
Vol 13 (1) ◽  
pp. e47
Author(s):  
P. Destefanis ◽  
A. Battaglia ◽  
M. Allasia ◽  
S. Chiesa ◽  
E. Garzino ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Phosphorylated Proteins ◽  
Diagnostic Validation

scholarly journals Early diagnosis of bladder cancer through the detection of urinary tyrosine-phosphorylated proteins

2015 ◽  
Vol 113 (3) ◽  
pp. 469-475 ◽  
Author(s):  
A Khadjavi ◽  
F Mannu ◽  
P Destefanis ◽  
C Sacerdote ◽  
A Battaglia ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Early Diagnosis ◽  
Phosphorylated Proteins

A high-throughput assay for the detection of Tyr-phosphorylated proteins in urine of bladder cancer patients

2013 ◽  
Vol 1830 (6) ◽  
pp. 3664-3669 ◽  
Author(s):  
A. Khadjavi ◽  
A. Notarpietro ◽  
F. Mannu ◽  
A. Pantaleo ◽  
E. Ferru ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
High Throughput ◽  
Phosphorylated Proteins ◽  
High Throughput Assay

scholarly journals Combination of urinary fibrinogen β-chain and tyrosine-phosphorylated proteins for the detection of bladder cancer

2021 ◽  
Author(s):  
Giuliana Giribaldi ◽  
Claudia Filippini ◽  
Clara Viberti ◽  
Amina Khadjavi ◽  
Nicole Finesso ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Accuracy ◽  
Smoking Habit ◽  
Low Grade ◽  
High Grade ◽  
Diagnostic Biomarker ◽  
Clinical Variables ◽  
Phosphorylated Proteins ◽  
Β Chain

Aim: to evaluate the performance of urinary fibrinogen β-chain (FBC) – either alone or associated with urinary tyrosine-phosphorylated proteins (UPY) – as bladder cancer (BCa) diagnostic biomarker. Materials & methods: 164 subjects were tested. Results: significantly different FBC and UPY levels were found between BCa patients and controls, as well as between low-grade and high-grade cancers. The diagnostic accuracy was 0.84 for FBC and 0.87 for UPY. The combination of FBC and UPY improved the accuracy to 0.91. The addition of clinical variables (age, gender, and smoking habit) to FBC and UPY into a model for BCa prediction significantly improved the accuracy to 0.99. The combination of FBC and UPY adjusted for clinical variables associates with the highest sensitivity and good specificity. Conclusion: urinary FBC and UPY could be used as biomarkers for BCa diagnosis.

Evidence of Abnormal Tyrosine Phosphorylated Proteins in the Urine of Patients With Bladder Cancer: The Road Toward a New Diagnostic Tool?

2011 ◽  
Vol 185 (5) ◽  
pp. 1922-1929 ◽  
Author(s):  
Amina Khadjavi ◽  
Giovanna Barbero ◽  
Paolo Destefanis ◽  
Giorgia Mandili ◽  
Giuliana Giribaldi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Diagnostic Tool ◽  
The Road ◽  
Phosphorylated Proteins

Sex and Racial Disparities in the Treatment and Outcomes of Muscle-invasive Bladder Cancer

Urology ◽  
2020 ◽  
Author(s):  
Jessica Marinaro ◽  
Alexander Zeymo ◽  
Jillian Egan ◽  
Filipe Carvalho ◽  
Ross Krasnow ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Racial Disparities ◽  
Invasive Bladder Cancer ◽  
Muscle Invasive Bladder Cancer ◽  
Muscle Invasive

775: Cell Culture Proteome Identifies CXCL 1 as a Secreted Marker and Mediator for the Tumor Invasion of Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 260-260 ◽  
Author(s):  
Hiroaki Kawanishi ◽  
Yoshiyuki Matsui ◽  
Toshinari Yamasaki ◽  
Takeshi Takahashi ◽  
Hiroyuki Nishiyama ◽  
...  
Keyword(s):  
Cell Culture ◽  
Bladder Cancer ◽  
Tumor Invasion

774: Improvement of Anti-Angiogenic and Anti-Tumorigenic Efficacy of Thrombospondin-1 by PPAR┌ Ligands in Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 259-259
Author(s):  
Thomas Nelius ◽  
Hanua Huang ◽  
Stephanie Filleur ◽  
Steven C. Campbell ◽  
Werner de Riese ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Thrombospondin 1 ◽  
Ppar Ligands

769: Matrix Metalloproteinase Polymorphisms are associated with Bladder Cancer Invasiveness

2007 ◽  
Vol 177 (4S) ◽  
pp. 258-258
Author(s):  
A. Karim Kader ◽  
Jun Liu ◽  
Una Shao ◽  
Colin P.N. Dinney ◽  
Jie Lin ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Matrix Metalloproteinase ◽  
Cancer Invasiveness

764: Differential Expression of RAL GTPases and their Effectors in Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 256-256
Author(s):  
Steven Smith ◽  
Gary Oxford ◽  
Dan Theodorescu
Keyword(s):  
Bladder Cancer ◽  
Differential Expression ◽  
Ral Gtpases
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