Chiral Diamine/Brønsted Acid Conjugates Confined in Mesoporous Silica as Catalyst for the Asymmetric Aldol Reaction

2009 ◽  
Vol 30 (7) ◽  
pp. 587-589 ◽  
Author(s):  
Hua LI ◽  
Xiaobing LÜ
Keyword(s):  
Mesoporous Silica ◽  
Aldol Reaction ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Asymmetric Aldol ◽  
Chiral Diamine ◽  
Brönsted Acid ◽  
Asymmetric Aldol Reaction

scholarly journals Brønsted Acid Catalyzed Asymmetric Aldol Reaction: A Complementary Approach to Enamine Catalysis

2010 ◽  
Vol 12 (16) ◽  
pp. 3582-3585 ◽  
Author(s):  
Guillaume Pousse ◽  
Fabien Le Cavelier ◽  
Luke Humphreys ◽  
Jacques Rouden ◽  
Jérôme Blanchet
Keyword(s):  
Aldol Reaction ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Asymmetric Aldol ◽  
Complementary Approach ◽  
Brönsted Acid ◽  
Asymmetric Aldol Reaction ◽  
Enamine Catalysis ◽  
Acid Catalyzed

A phosphotungstic acid-supported multifunctional organocatalyst containing 9-amino(9-deoxy)epi-cinchonidine and Brønsted acid and its application in asymmetric aldol reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (61) ◽  
pp. 55894-55902 ◽  
Author(s):  
Ling Lan ◽  
Guangxin Xie ◽  
Tao Wu ◽  
Dandan Feng ◽  
Xuebing Ma
Keyword(s):  
Phosphotungstic Acid ◽  
Aldol Reaction ◽  
Catalytic Performance ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Asymmetric Aldol ◽  
Brönsted Acid ◽  
Asymmetric Aldol Reaction ◽  
First Time ◽  
Excellent Catalytic Performance

Phosphotungstic acid-supported multifunctional 9-amino(9-deoxy)epi-cinchonidine containing Brønsted acid was developed through facile precipitation for the first time and afforded aldol adducts in excellent catalytic performance with good reusability.

Alternating chiral selectivity of aldol reactions under the confined space of mesoporous silica

2015 ◽  
Vol 51 (96) ◽  
pp. 17116-17119 ◽  
Author(s):  
Chewei Yeh ◽  
Yan-Ru Sun ◽  
Shing-Jong Huang ◽  
Yeun-Min Tsai ◽  
Soofin Cheng
Keyword(s):  
Mesoporous Silica ◽  
Aldol Reaction ◽  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Water Medium ◽  
Confined Space ◽  
Asymmetric Aldol ◽  
Co Catalysts ◽  
Asymmetric Aldol Reaction ◽  
Chiral Selectivity

The chiral selectivities were altered and high diastereo- and enantio-selectivities of the products were obtained in water medium without adding acid co-catalysts when a primary–tertiary diamine catalyst was immobilized on mesoporous SBA-15 to form a recyclable catalyst for the direct asymmetric aldol reaction of cyclohexanone with p-nitrobenzaldehyde.

scholarly journals Straightforward Immobilization of Phosphonic Acids and Phosphoric Acid Esters on Mesoporous Silica and Their Application in an Asymmetric Aldol Reaction

Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 249 ◽  
Author(s):  
Christian Weinberger ◽  
Tatjana Heckel ◽  
Patrick Schnippering ◽  
Markus Schmitz ◽  
Anpeng Guo ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Phosphoric Acid ◽  
Surface Area ◽  
Aldol Reaction ◽  
Synthesis Method ◽  
Mesoporous Silicas ◽  
Phosphonic Acids ◽  
Asymmetric Aldol ◽  
Asymmetric Aldol Reaction ◽  
Acid Esters

The combined benefits of moisture-stable phosphonic acids and mesoporous silica materials (SBA-15 and MCM-41) as large-surface-area solid supports offer new opportunities for several applications, such as catalysis or drug delivery. We present a comprehensive study of a straightforward synthesis method via direct immobilization of several phosphonic acids and phosphoric acid esters on various mesoporous silicas in a Dean–Stark apparatus with toluene as the solvent. Due to the utilization of azeotropic distillation, there was no need to dry phosphonic acids, phosphoric acid esters, solvents, or silicas prior to synthesis. In addition to modeling phosphonic acids, immobilization of the important biomolecule adenosine monophosphate (AMP) on the porous supports was also investigated. Due to the high surface area of the mesoporous silicas, a possible catalytic application based on immobilization of an organocatalyst for an asymmetric aldol reaction is discussed.

Catalyst-free synthesis of α1-oxindole-α-hydroxyphosphonates via phospha-aldol reaction of isatins employing N-heterocyclic phosphine (NHP)-thiourea

2016 ◽  
Vol 14 (38) ◽  
pp. 8952-8956 ◽  
Author(s):  
Nagaraju Molleti ◽  
Jun Yong Kang
Keyword(s):  
Critical Role ◽  
Aldol Reaction ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Catalyst Free ◽  
Brönsted Acid

A catalyst-free phospha-aldol reaction of isatins with NHP-thiourea has been developed and the critical role of the Brønsted acid in this transformation is unveiled.

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