scholarly journals P009 The long-term therapeutic effect of bone marrow-derived mesenchymal stem cells in a dextran sulfate sodium-induced murine colitis

2014 ◽  
Vol 8 ◽  
pp. S68
Author(s):  
H.J. Lee ◽  
H.W. Jang ◽  
J.-H. Kwon ◽  
K.J. Lee ◽  
S.J. Park ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Effect ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Murine Colitis

scholarly journals Long-Term Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Dextran Sulfate Sodium-Induced Murine Chronic Colitis

Gut and Liver ◽  
2016 ◽  
Vol 10 (3) ◽  
Author(s):  
Hyun Jung Lee ◽  
Sun-Hee Oh ◽  
Hui Won Jang ◽  
Ji-Hee Kwon ◽  
Kyoung Jin Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Long Term Effects ◽  
Chronic Colitis

scholarly journals Negative impact of bone-marrow-derived mesenchymal stem cells on dextran sulfate sodium-induced colitis

2015 ◽  
Vol 21 (7) ◽  
pp. 2030-2039 ◽  
Author(s):  
Young-Sun Nam ◽  
Nayoun Kim ◽  
Keon-Il Im ◽  
Jung-Yeon Lim ◽  
Eun-Sol Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Negative Impact

scholarly journals Therapeutic potential of tonsil-derived mesenchymal stem cells in dextran sulfate sodium-induced experimental murine colitis

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183141 ◽  
Author(s):  
Yeonsil Yu ◽  
Eun Mi Song ◽  
Ko Eun Lee ◽  
Yang-Hee Joo ◽  
Seong-Eun Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Therapeutic Potential ◽  
Murine Colitis

Evaluation of Canine Bone Marrow-derived Mesenchymal Stem Cells After Long-term Cryopreservation

2013 ◽  
Vol 30 (12) ◽  
pp. 1032-1037 ◽  
Author(s):  
Xiaofeng Zhu ◽  
Fang Yuan ◽  
Houxuan Li ◽  
Yuqian Zheng ◽  
Yin Xiao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells

Effects Of Hypoxia in Long-Term In Vitro Expansion of Human Bone Marrow Derived Mesenchymal Stem Cells

2017 ◽  
Vol 118 (10) ◽  
pp. 3072-3079 ◽  
Author(s):  
Annelise Pezzi ◽  
Bruna Amorin ◽  
Álvaro Laureano ◽  
Vanessa Valim ◽  
Alice Dahmer ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
In Vitro Expansion

Kartogenin enhances the therapeutic effect of bone marrow mesenchymal stem cells derived exosomes in cartilage repair

Nanomedicine ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. 273-288 ◽  
Author(s):  
Chun Liu ◽  
Yun Li ◽  
Zhijian Yang ◽  
Zhiyou Zhou ◽  
Zhihao Lou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Effect ◽  
Bone Marrow Mscs ◽  
In Vivo Experiments ◽  
Marrow Mesenchymal Stem Cells ◽  
Cartilage Diseases

The effectiveness of mesenchymal stem cells (MSC) in the treatment of cartilage diseases has been demonstrated to be attributed to the paracrine mechanisms, especially the mediation of exosomes. But the exosomes derived from unsynchronized MSCs may be nonhomogeneous and the therapeutic effect varies between samples. Aim: To produce homogeneous and more effective exosomes for the regeneration of cartilage. Materials & methods: In this study we produced specific exosomes from bone marrow MSCs (BMSC) through kartogenin (KGN) preconditioning and investigated their performance in either in vitro or in vivo experiments. Results & conclusion: The exosomes derived from KGN-preconditioned BMSCs (KGN-BMSC-Exos) performed more effectively than the exosomes derived from BMSCs (BMSC-Exos). KGN preconditioning endowed BMSC-Exos with stronger chondral matrix formation and less degradation.

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