scholarly journals Super-resolution reconstruction of turbulent flows with machine learning

2019 ◽  
Vol 870 ◽  
pp. 106-120 ◽  
Author(s):  
Kai Fukami ◽  
Koji Fukagata ◽  
Kunihiko Taira

We use machine learning to perform super-resolution analysis of grossly under-resolved turbulent flow field data to reconstruct the high-resolution flow field. Two machine learning models are developed, namely, the convolutional neural network (CNN) and the hybrid downsampled skip-connection/multi-scale (DSC/MS) models. These machine learning models are applied to a two-dimensional cylinder wake as a preliminary test and show remarkable ability to reconstruct laminar flow from low-resolution flow field data. We further assess the performance of these models for two-dimensional homogeneous turbulence. The CNN and DSC/MS models are found to reconstruct turbulent flows from extremely coarse flow field images with remarkable accuracy. For the turbulent flow problem, the machine-leaning-based super-resolution analysis can greatly enhance the spatial resolution with as little as 50 training snapshot data, holding great potential to reveal subgrid-scale physics of complex turbulent flows. With the growing availability of flow field data from high-fidelity simulations and experiments, the present approach motivates the development of effective super-resolution models for a variety of fluid flows.

2019 ◽  
Author(s):  
Hao Qin ◽  
Vishal Srivastava ◽  
Hua Wang ◽  
Luis E. Zerpa ◽  
Carolyn A. Koh

2021 ◽  
Author(s):  
Vadim Zinchuk ◽  
Olga Grossenbacher-Zinchuk

Abstract Machine Learning offers the opportunity to visualize the invisible in conventional fluorescence microscopy images by improving their resolution while preserving and enhancing image details. This protocol describes the application of GAN-based Machine Learning models to transform the resolution of conventional fluorescence microscopy images to a resolution comparable with super-resolution. It provides a flexible environment using a modern app functioning on both desktop and mobile computers. This approach can be extended for use on other types of microscopy images empowering life science researchers with modern analytical tools.


2020 ◽  
Vol 2 (1) ◽  
pp. 3-6
Author(s):  
Eric Holloway

Imagination Sampling is the usage of a person as an oracle for generating or improving machine learning models. Previous work demonstrated a general system for using Imagination Sampling for obtaining multibox models. Here, the possibility of importing such models as the starting point for further automatic enhancement is explored.


2021 ◽  
Author(s):  
Norberto Sánchez-Cruz ◽  
Jose L. Medina-Franco

<p>Epigenetic targets are a significant focus for drug discovery research, as demonstrated by the eight approved epigenetic drugs for treatment of cancer and the increasing availability of chemogenomic data related to epigenetics. This data represents a large amount of structure-activity relationships that has not been exploited thus far for the development of predictive models to support medicinal chemistry efforts. Herein, we report the first large-scale study of 26318 compounds with a quantitative measure of biological activity for 55 protein targets with epigenetic activity. Through a systematic comparison of machine learning models trained on molecular fingerprints of different design, we built predictive models with high accuracy for the epigenetic target profiling of small molecules. The models were thoroughly validated showing mean precisions up to 0.952 for the epigenetic target prediction task. Our results indicate that the herein reported models have considerable potential to identify small molecules with epigenetic activity. Therefore, our results were implemented as freely accessible and easy-to-use web application.</p>


2020 ◽  
Author(s):  
Shreya Reddy ◽  
Lisa Ewen ◽  
Pankti Patel ◽  
Prerak Patel ◽  
Ankit Kundal ◽  
...  

<p>As bots become more prevalent and smarter in the modern age of the internet, it becomes ever more important that they be identified and removed. Recent research has dictated that machine learning methods are accurate and the gold standard of bot identification on social media. Unfortunately, machine learning models do not come without their negative aspects such as lengthy training times, difficult feature selection, and overwhelming pre-processing tasks. To overcome these difficulties, we are proposing a blockchain framework for bot identification. At the current time, it is unknown how this method will perform, but it serves to prove the existence of an overwhelming gap of research under this area.<i></i></p>


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