Triplets and Higher Order Multiple Births in Japan

1990 ◽  
Vol 39 (3) ◽  
pp. 295-306 ◽  
Author(s):  
Y. Imaizumi
Keyword(s):  
In Vitro Fertilization ◽  
Birth Rate ◽  
Average Rate ◽  
Vital Statistics ◽  
Multiple Births ◽  
Multiple Birth ◽  
Stillbirth Rate ◽  
Birth Rates ◽  
Vitro Fertilization

AbstractMultiple birth rates in entire Japan were analyzed using vital statistics for 1951 to 1988. The triplet rate was nearly constant from 1951 to 1974, where the rate per million births was 58, then increased with the year up to 1982 (104), and decreased up to 1984, and suddenly increased thereafter (109 in 1987). The average rate of quadruplets per million births from 1951 to 1968 was 0.93, then increased with the year up to 1975 (7.5), and decreased until 1984 and suddenly increased thereafter (10.6 in 1987). The rate of quintuplets was 0.77 per million births during the period from 1975 to 1987. The higher multiple birth rate since 1975 was attributed to the higher proportion of mothers treated with ovulation-inducing hormones in Japan. Since 1985, higher multiple birth rates might be partially attributed to in vitro fertilization. The stillbirth rates for male triplets gradually decreased from 1960 to 1978 and thereafter remained constant at a little higher level except in 1988, whereas the rates for females gradually decreased with the year. The overall stillbirth rates decreased to 1/4 for triplets and to 1/5 for quadruplets during the 37-year period from 1951. The overall stillbirth rate of quintuplets was 0.60 (51/85) during the period 1975-1987.

scholarly journals Multiple births and maternal mental health from pregnancy to 5 years after birth: A longitudinal population-based cohort study

2014 ◽  
Vol 24 (1-2) ◽  
Author(s):  
Eivind Ystrom ◽  
Ted Reichborn-Kjennerud ◽  
Kristian Tambs ◽  
Per Magnus ◽  
Anne Mari Torgersen ◽  
...  
Keyword(s):  
Mental Health ◽  
Cohort Study ◽  
In Vitro Fertilization ◽  
Maternal Mental Health ◽  
Population Based ◽  
Multiple Births ◽  
Multiple Birth ◽  
Vitro Fertilization ◽  
Risk For Depression

<p><em>Background:</em> There is a lack of population-based studies on multiple births and maternal mental health. Having a high-risk pregnancy by bearing two or more children is a stressful life event, and the challenges of parenting two or more children probably also lead to a high level of parental stress. There are a few results on multiple births and maternal mental health from studies on in vitro fertilization samples. The only previous cohort study on multiple birth and maternal mental health included a single measure of depressive symptoms at 9 months postpartum. We aim to estimate the relative risk for depression and anxiety after multiple birth in a population-based prospective cohort study while adjusting for factors prior and subsequent to fertilization.</p><p><em>Methods</em>: We used data from 87,807 pregnancies included in the Norwegian Mother and Child Cohort study. Information on multiple birth was retrieved from the Norwegian Medical Birth Registry, and maternal mental health was assessed at 17th and 30th week of gestation and 0.5, 1.5, 3, and 5 years postpartum. There were 1,842 plural births included in the study (i.e. 1,821 twin births and 21 higher order births). We predicted maternal mental health at each time point, subsequently adjusting for 1) factors prior to fertilization (e.g. maternal age and in vitro fertilization); 2) factors during pregnancy (e.g. hypertensive states); 3) factors at delivery (e.g. cesarean section); 4) child-related postnatal complications (e.g. intracranial hemorrhage); and 5) concurrent depression or anxiety after pregnancy.</p><p><em>Results</em>: Adjusted for antecedents of plural birth, mothers expecting a plural birth had a normal risk for anxiety (RR=1.05; 95% CI 0.92-1.20) and depression (RR=1.02; 95% CI 0.89-1.16) at 17th week of gestation. However, plural birth was associated with maternal depression at 1.5, 3, and 5 years postpartum and maternal anxiety at 3 years postpartum. The trend was for the association to increase across time, and mothers of multiplets had a significant higher risk for depression at 5 years (RR=1.77; 95% CI 1.33-2.35). Fully adjusted the RR for depression was 1.51 (95% CI 1.10-2.08). By adjusting depression for concurrent anxiety, and vice versa we found the effect of multiple pregnancy to be specific to depression and not anxiety.</p><p><em>Conclusions:</em> Mothers expecting multiplets have normal mental health during pregnancy. After birth there is an increasing risk for depression up to 5 years of age. Our findings indicate that more is simply more, and mothers of multiplets have need for additional support several years postpartum</p>

Stillbirth Rates in Singletons, Twins and Triplets in Sweden, 1869 to 2001

2006 ◽  
Vol 9 (2) ◽  
pp. 260-265 ◽  
Author(s):  
Johan Fellman ◽  
Aldur W. Eriksson
Keyword(s):  
In Vitro Fertilization ◽  
Marked Effect ◽  
Multiple Births ◽  
Stillbirth Rate ◽  
Artificial Reproduction ◽  
Vitro Fertilization ◽  
Birth Data ◽  
Definition Of ◽  
Made In

AbstractThe temporal variation in the stillbirth rates (SBR), measured as the number of stillborn per 1000 total births, among singletons, twins and triplets was studied on Swedish birth data for the period 1869 to 2001 and comparisons with data from other populations were made. Among both single and multiple births there were marked, almost monotonously decreasing trends in the stillbirth rates. Among singletons the stillbirth rate decreased from 29.5 per 1000 in the period 1869 to 1878 to 3.4 in the period 1991 to 2001. Among twins the stillbirth rate decreased from 94 per 1000 in 1869 to 1878 to a minimum of 8.2 in 1991 to 2001 and among triplets from 166 per 1000 to a minimum of 19.8. The relative declining pattern in the SBRs was almost the same, being 88% among singletons, 91% among twins and 88% among triplets. In the 1980s and 1990s the definition of the stillbirth rate was changed in many countries, including Finland, but no changes in the definition of stillbirths have been made in Sweden. The effect of the artificial reproduction techniques, including in vitro fertilization, on the rates of multiple maternities is also discussed. It was noted especially that they had a more marked effect on the triplet than on the twinning rate.

State Insurance Mandates and Multiple Birth Rates After In Vitro Fertilization

2016 ◽  
Vol 128 (6) ◽  
pp. 1205-1214 ◽  
Author(s):  
Meredith P. Provost ◽  
Samantha M. Thomas ◽  
Jason S. Yeh ◽  
William W. Hurd ◽  
Jennifer L. Eaton
Keyword(s):  
In Vitro Fertilization ◽  
Multiple Birth ◽  
Birth Rates ◽  
Vitro Fertilization ◽  
Insurance Mandates

The impact of insurance mandates on multiple birth rates following in vitro fertilization

2015 ◽  
Vol 104 (3) ◽  
pp. e16
Author(s):  
M.P. Provost ◽  
J.S. Yeh ◽  
S.M. Thomas ◽  
W.W. Hurd ◽  
J.L. Eaton
Keyword(s):  
In Vitro Fertilization ◽  
Multiple Birth ◽  
Birth Rates ◽  
Vitro Fertilization ◽  
Insurance Mandates ◽  
The Impact

scholarly journals Progesterone levels predict pregnancy outcome in individuals with fallopian tube associated infertility

2020 ◽  
Author(s):  
Wenjia BO ◽  
Ning Zhang
Keyword(s):  
In Vitro Fertilization ◽  
Fallopian Tube ◽  
Live Birth ◽  
Pregnancy Outcomes ◽  
Birth Rate ◽  
Clinical Pregnancy ◽  
Birth Rates ◽  
Vitro Fertilization ◽  
Live Birth Rates

Abstract Background: To investigate the predictive value of human chorionic gonadotropin and progesterone levels on pregnancy outcomes in patients receiving in vitro fertilization due to simple fallopian tube factors. METHODS:We retrospectively analyzed the clinical data of 854 cycles from the simple fallopian tube factor in vitro fertilization fresh embryo transfer. The clinical data of 854 cycles from January 2010 to December 2018 was divided into 7 groups according to the progesterone level on human chrionic gonadotropin day. Live birth rates and observe trends were calculated. The receiver operating characteristic curve was established to determine the optimal cutoff value for progesterone, which was used to further divide the data into 3 groups: Group 1 (progesterone ≦ 1.0 ng/ml), Group 2 (1.0 ng/ml ≤ progesterone ≤ 1.25 ng/ml), and Group 3 (progesterone≥1.25ng/ml). We then compared the ovulation results and clinical outcomes between the 3 groups. RESULTS There were no significant differences in age, infertility years, Gonadotropin dosage, Gonadotropin days, Luteinizing hormone level on human chrionic gonadotropinday, 2pronuclear fertilization rate, clinical pregnancy rate, live birth rates, full-term birth rate, and preterm birth rate among the three groups, but body mass index(P = 0.001), basal luteinizing hormone (P = 0.034), estrogen peak (P ＜0.001), number of oocytes obtained (P＜0.001) were significantly different. CONCLUSION The level of progesterone on human chrionic gonadotropin day does not affect the clinical pregnancy rate and live birth rates after in vitro fertilization. However, progesterone levels between 1.0-1.25ng/ml may lead to good clinical pregnancy outcomes.

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