A standardized monitor for the control of ethylene oxide sterilization cycles
Keyword(s):
SUMMARYThe resistance of spores ofB. subtilisvar.nigerproduced in liquid synthetic medium and exposed to ethylene oxide on a nylon surface, has been shown to be almost identical to that for spores produced on a traditional solidified complex medium with exposure to the sterilant on aluminium foil. The use of short lengths of nylon tube as carriers allowed easy production and handling, with self-protection of the spore-bearing surface. Addition of a dye provided visual evidence of inoculation without affecting resistance to ethylene oxide. Such a monitor is suitable for use as a standardized biological challenge in routine ethylene oxide sterilization cycles.
1994 ◽
Vol 65
(6)
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pp. 640-642
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2019 ◽
Vol 108
(1)
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pp. 770-774
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1993 ◽
Vol 64
(1)
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pp. 103-108
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1970 ◽
Vol 19
(1)
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pp. 146-151
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