scholarly journals The production of pyrogenic exotoxins by group A streptococci

1985 ◽  
Vol 95 (1) ◽  
pp. 47-57 ◽  
Author(s):  
Gillian Hallas
Keyword(s):  
Sore Throat ◽  
Isoelectric Focusing ◽  
Scarlet Fever ◽  
Group A Streptococci ◽  
Polyacrylamide Gels ◽  
Agar Gels ◽  
Group A ◽  
Sporadic Cases ◽  
Spe B ◽  
Lancefield Group

SUMMARYLancefield group A streptococci isolated from recent outbreaks and sporadic cases of scarlet fever were restricted to the following M types 1, 3, 4, 6, 12, 18, 22 and 66. These strains were examined for the presence of streptococcal pyrogenic exotoxins (SPE) types A, B and C by isoelectric focusing in polyacrylamide gels and by immunoprecipitation in agar gels. SPE B was produced by 70% of the strains and SPEC by 40%. SPE A could not be detected in these strains. In contrast, SPE type A was found in 4 of 10 strains, held by the NCTC, that had been isolated before 1940 from patients with scarlet fever. Nine of 12 recent isolates from patients with sore throat uncomplicated by a rash produced SPE C and 4 of these also produced SPE B.

scholarly journals Streptococcal pharyngitis in general practice. 1. Some unusual features of the epidemiology

1992 ◽  
Vol 109 (2) ◽  
pp. 181-189 ◽  
Author(s):  
P. M. Higgins
Keyword(s):  
Sore Throat ◽  
Age Distribution ◽  
Positive Culture ◽  
Streptococcal Pharyngitis ◽  
Group A Streptococci ◽  
Upper Respiratory Tract ◽  
Acute Infections ◽  
Group A ◽  
Upper Respiratory ◽  
Highly Correlated

SUMMARYThis report is based on a study of acute infections of the upper respiratory tract in 1965 and detailed records of such infections in 1963 and 1964. A change from illnesses mainly yielding viruses to illnesses mainly yielding group A streptococci was noted around the age of 5 years. A positive culture for group A streptococci in patients over 4 years of age was highly correlated with a complaint of sore throat and with serological evidence of streptococcal infection. A bimodal age distribution curve for pharyngitis associated with a positive culture for group A streptococci was consistently noted. The incidence was highest in children aged 5–9 but a second smaller peak occurred among adults in the 30–39 age group. The evidence suggests that being female increases the risk of acquiring group A streptococci and of experiencing sore throat.

scholarly journals Antibody to streptococcal opacity factor in human sera

1973 ◽  
Vol 71 (1) ◽  
pp. 35-42 ◽  
Author(s):  
W. R. Maxted ◽  
Jean P. Widdowson ◽  
Cherry A. M. Fraser
Keyword(s):  
Sore Throat ◽  
Group A Streptococci ◽  
Close Correspondence ◽  
Human Sera ◽  
Group A

SUMMARYTwo tests are described for detecting antibody to the type-specific opacity factor (OF) of group A streptococci. This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which out-breaks due to opacity factor-producing strains of group A streptococci occurred.In an outbreak due to streptococci of M-type 22 there was a close correspondence between the distribution of anti-OF and of bactericidal M-antibody for the type. In a smaller outbreak due to M-type 58 streptococci, however, M-antibody was detected more often than antibody of OF.

scholarly journals Milk epidemic of angina, originating from a Cow with mastitis and due to Streptococcus pyogenes (Lancefield group A)

1938 ◽  
Vol 38 (3) ◽  
pp. 384-391 ◽  
Author(s):  
E. Juel Henningsen ◽  
J. Ernst
Keyword(s):  
Sore Throat ◽  
Streptococcus Pyogenes ◽  
Raw Milk ◽  
Slight Degree ◽  
Group A ◽  
The Village ◽  
Lancefield Group

A report is given of a milk epidemic of septic sore throat, comprising about 100 cases.The epidemic originated from a cow with a slight degree of mastitis, produced by a Streptococcus pyogenes (Lancefield's group A).The same Streptococcus (which we did not succeed in typing) was isolated from 74% of the patients examined and from three persons who were handling the milk.It seems reasonable to assume that the cow was infected from the milkers. Owing to particular conditions in the distribution of the raw milk, it is possible that the milk delivered raw in the village involved on one day a massive contamination.The epidemic is characterized as moderately severe. No case terminated fatally.

β-Haemolytic group A streptococci emm75 carrying altered pyrogenic exotoxin A linked to scarlet fever in adults

2008 ◽  
Vol 56 (4) ◽  
pp. 261-267 ◽  
Author(s):  
Hongjun Dong ◽  
Guozhang Xu ◽  
Shuhua Li ◽  
Qifa Song ◽  
Shijian Liu ◽  
...  
Keyword(s):  
Scarlet Fever ◽  
Group A Streptococci ◽  
Exotoxin A ◽  
Group A

scholarly journals Food-borne outbreak of group G streptococcal sore throat in an Israeli military base

1987 ◽  
Vol 99 (2) ◽  
pp. 249-255 ◽  
Author(s):  
D. Cohen ◽  
M. Ferne ◽  
T. Rouach ◽  
S. Bergner-Rabinowitz
Keyword(s):  
Sore Throat ◽  
The Body ◽  
Food Handler ◽  
Group G Streptococci ◽  
Source Of Infection ◽  
Food Borne ◽  
Military Camp ◽  
Group A ◽  
Laboratory Investigations ◽  
Lancefield Group

SUMMARYA food-borne outbreak of sore throat caused by Lancefield group G β-haemolytic streptococci and involving 50 persons occurred in May 1983 in an Israeli military camp. All of the patients available for clinical examination had sore throat and difficulty in swallowing. Exudative tonsillitis occurred in 46% of the patients and the body temperature was above 37·5 °C in 81%. The pattern of attack was uniform over the base and 37 became ill during the night and morning of the 5 May. Thirty-two (84%) of the throat cultures taken from 37 patients grew group G β-haemolytic streptococci. Eight of 29 contacts were positive for group G β-haemolytic streptococci and 6 of the 28 foodhandlers examined had positive cultures of the same group. The organism was also isolated from one food sample. The epidemiological and laboratory investigations indicated that a food handler, a convalescent carrier of group G streptococci, might have been the source of infection. Assumptions on the potential of non-group A streptococci to cause epidemics are discussed.

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